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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRIQ2
Full Name:
Centrosomal protein of 97 kDa
Alias:
CEP97; Leucine-rich repeat and IQ domain-containing 2
Type:
Mass (Da):
96981
Number AA:
865
UniProt ID:
Q8IW35
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005815
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
A
L
P
P
G
E
G
S
V
V
N
W
S
G
Q
Site 2
T40
P
C
E
A
D
I
H
T
L
I
L
D
K
N
Q
Site 3
S122
K
A
M
E
Q
I
N
S
C
T
A
L
Q
H
L
Site 4
S132
A
L
Q
H
L
D
L
S
D
N
N
I
S
Q
I
Site 5
S137
D
L
S
D
N
N
I
S
Q
I
G
D
L
S
K
Site 6
S176
P
R
S
L
A
I
L
S
L
A
E
N
E
I
R
Site 7
T211
N
N
P
C
V
M
A
T
P
S
I
P
G
F
D
Site 8
Y219
P
S
I
P
G
F
D
Y
R
P
Y
I
V
S
W
Site 9
Y222
P
G
F
D
Y
R
P
Y
I
V
S
W
C
L
N
Site 10
Y236
N
L
R
V
L
D
G
Y
V
I
S
Q
K
E
S
Site 11
S239
V
L
D
G
Y
V
I
S
Q
K
E
S
L
K
A
Site 12
S243
Y
V
I
S
Q
K
E
S
L
K
A
E
W
L
Y
Site 13
Y250
S
L
K
A
E
W
L
Y
S
Q
G
K
G
R
A
Site 14
S251
L
K
A
E
W
L
Y
S
Q
G
K
G
R
A
Y
Site 15
Y258
S
Q
G
K
G
R
A
Y
R
P
G
Q
H
I
Q
Site 16
S295
A
K
L
E
K
I
L
S
K
Q
R
F
H
Q
R
Site 17
S308
Q
R
Q
L
M
N
Q
S
Q
N
E
E
L
S
P
Site 18
S314
Q
S
Q
N
E
E
L
S
P
L
V
P
V
E
T
Site 19
S324
V
P
V
E
T
R
A
S
L
I
P
E
H
S
S
Site 20
S330
A
S
L
I
P
E
H
S
S
P
V
Q
D
C
Q
Site 21
S331
S
L
I
P
E
H
S
S
P
V
Q
D
C
Q
I
Site 22
S339
P
V
Q
D
C
Q
I
S
Q
E
S
E
P
V
I
Site 23
S371
V
K
N
N
F
P
A
S
V
H
T
T
R
Y
S
Site 24
T374
N
F
P
A
S
V
H
T
T
R
Y
S
R
N
D
Site 25
T375
F
P
A
S
V
H
T
T
R
Y
S
R
N
D
L
Site 26
Y377
A
S
V
H
T
T
R
Y
S
R
N
D
L
H
L
Site 27
S378
S
V
H
T
T
R
Y
S
R
N
D
L
H
L
E
Site 28
T389
L
H
L
E
D
I
Q
T
D
E
D
K
L
N
C
Site 29
S397
D
E
D
K
L
N
C
S
L
L
S
S
E
S
T
Site 30
S400
K
L
N
C
S
L
L
S
S
E
S
T
F
M
P
Site 31
S403
C
S
L
L
S
S
E
S
T
F
M
P
V
A
S
Site 32
S413
M
P
V
A
S
G
L
S
P
L
S
P
T
V
E
Site 33
S416
A
S
G
L
S
P
L
S
P
T
V
E
L
R
L
Site 34
T418
G
L
S
P
L
S
P
T
V
E
L
R
L
Q
G
Site 35
S439
D
D
G
V
A
D
E
S
V
K
G
L
E
S
Q
Site 36
S445
E
S
V
K
G
L
E
S
Q
V
L
D
K
E
E
Site 37
T473
M
M
R
S
E
I
N
T
E
V
N
E
K
A
G
Site 38
S500
I
L
K
D
D
N
H
S
L
T
F
F
P
E
S
Site 39
T502
K
D
D
N
H
S
L
T
F
F
P
E
S
T
E
Site 40
S507
S
L
T
F
F
P
E
S
T
E
Q
K
Q
S
D
Site 41
S513
E
S
T
E
Q
K
Q
S
D
I
K
K
P
E
N
Site 42
T528
T
Q
P
E
N
K
E
T
I
S
Q
A
T
S
E
Site 43
S530
P
E
N
K
E
T
I
S
Q
A
T
S
E
K
L
Site 44
S534
E
T
I
S
Q
A
T
S
E
K
L
P
M
I
L
Site 45
T542
E
K
L
P
M
I
L
T
Q
R
S
V
A
L
G
Site 46
Y577
R
G
F
Y
A
R
N
Y
N
P
Q
A
K
D
V
Site 47
Y586
P
Q
A
K
D
V
R
Y
E
I
R
L
R
R
M
Site 48
T641
S
L
Q
V
W
Q
Q
T
V
D
Q
R
L
S
S
Site 49
S647
Q
T
V
D
Q
R
L
S
S
W
H
T
D
V
P
Site 50
S648
T
V
D
Q
R
L
S
S
W
H
T
D
V
P
P
Site 51
T651
Q
R
L
S
S
W
H
T
D
V
P
P
I
S
S
Site 52
S657
H
T
D
V
P
P
I
S
S
T
L
V
P
S
K
Site 53
T659
D
V
P
P
I
S
S
T
L
V
P
S
K
H
P
Site 54
S663
I
S
S
T
L
V
P
S
K
H
P
L
F
T
Q
Site 55
T669
P
S
K
H
P
L
F
T
Q
S
Q
E
S
S
C
Site 56
S671
K
H
P
L
F
T
Q
S
Q
E
S
S
C
D
Q
Site 57
S686
N
A
D
W
F
I
A
S
D
V
A
P
Q
E
K
Site 58
S694
D
V
A
P
Q
E
K
S
L
P
E
F
P
D
S
Site 59
S701
S
L
P
E
F
P
D
S
G
F
H
S
S
L
T
Site 60
S705
F
P
D
S
G
F
H
S
S
L
T
E
Q
V
H
Site 61
S706
P
D
S
G
F
H
S
S
L
T
E
Q
V
H
S
Site 62
T708
S
G
F
H
S
S
L
T
E
Q
V
H
S
L
Q
Site 63
S713
S
L
T
E
Q
V
H
S
L
Q
H
S
L
D
F
Site 64
S717
Q
V
H
S
L
Q
H
S
L
D
F
E
K
S
S
Site 65
S723
H
S
L
D
F
E
K
S
S
T
E
G
S
E
S
Site 66
S724
S
L
D
F
E
K
S
S
T
E
G
S
E
S
S
Site 67
T725
L
D
F
E
K
S
S
T
E
G
S
E
S
S
I
Site 68
S728
E
K
S
S
T
E
G
S
E
S
S
I
M
G
N
Site 69
S730
S
S
T
E
G
S
E
S
S
I
M
G
N
S
I
Site 70
S731
S
T
E
G
S
E
S
S
I
M
G
N
S
I
D
Site 71
S736
E
S
S
I
M
G
N
S
I
D
T
V
R
Y
G
Site 72
T739
I
M
G
N
S
I
D
T
V
R
Y
G
K
E
S
Site 73
S746
T
V
R
Y
G
K
E
S
D
L
G
D
V
S
E
Site 74
S752
E
S
D
L
G
D
V
S
E
E
H
G
E
W
N
Site 75
S763
G
E
W
N
K
E
S
S
N
N
E
Q
D
N
S
Site 76
S770
S
N
N
E
Q
D
N
S
L
L
E
Q
Y
L
T
Site 77
T777
S
L
L
E
Q
Y
L
T
S
V
Q
Q
L
E
D
Site 78
T793
D
E
R
T
N
F
D
T
E
T
R
D
S
K
L
Site 79
T795
R
T
N
F
D
T
E
T
R
D
S
K
L
H
I
Site 80
T811
C
F
P
V
Q
L
D
T
L
S
D
G
A
S
V
Site 81
S813
P
V
Q
L
D
T
L
S
D
G
A
S
V
D
E
Site 82
S817
D
T
L
S
D
G
A
S
V
D
E
S
H
G
I
Site 83
S821
D
G
A
S
V
D
E
S
H
G
I
S
P
P
L
Site 84
S825
V
D
E
S
H
G
I
S
P
P
L
Q
G
E
I
Site 85
S833
P
P
L
Q
G
E
I
S
Q
T
Q
E
N
S
K
Site 86
T835
L
Q
G
E
I
S
Q
T
Q
E
N
S
K
L
N
Site 87
S854
G
Q
Q
P
E
C
D
S
T
F
Q
L
L
H
V
Site 88
T855
Q
Q
P
E
C
D
S
T
F
Q
L
L
H
V
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation