KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
C19orf21
Full Name:
Uncharacterized protein C19orf21
Alias:
CS021; DKFZp686H18209; LOC126353
Type:
Transcription protein, coactivator/corepressor
Mass (Da):
75357
Number AA:
679
UniProt ID:
Q8IVT2
International Prot ID:
IPI00217121
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
D
R
V
T
R
Y
P
I
L
G
I
P
Q
Site 2
T19
I
P
Q
A
H
R
G
T
G
L
V
L
D
G
D
Site 3
S28
L
V
L
D
G
D
T
S
Y
T
Y
H
L
V
C
Site 4
Y31
D
G
D
T
S
Y
T
Y
H
L
V
C
M
G
P
Site 5
Y68
V
Q
R
Q
G
V
S
Y
S
V
H
A
Y
T
G
Site 6
S69
Q
R
Q
G
V
S
Y
S
V
H
A
Y
T
G
Q
Site 7
Y73
V
S
Y
S
V
H
A
Y
T
G
Q
P
S
P
R
Site 8
T74
S
Y
S
V
H
A
Y
T
G
Q
P
S
P
R
G
Site 9
S78
H
A
Y
T
G
Q
P
S
P
R
G
L
H
S
E
Site 10
S84
P
S
P
R
G
L
H
S
E
N
R
E
D
E
G
Site 11
Y95
E
D
E
G
W
Q
V
Y
R
L
G
A
R
D
A
Site 12
T108
D
A
H
Q
G
R
P
T
W
A
L
R
P
E
D
Site 13
T123
G
E
D
K
E
M
K
T
Y
R
L
D
A
G
D
Site 14
Y124
E
D
K
E
M
K
T
Y
R
L
D
A
G
D
A
Site 15
S155
Q
G
Q
A
V
R
K
S
S
T
V
A
T
L
Q
Site 16
S156
G
Q
A
V
R
K
S
S
T
V
A
T
L
Q
G
Site 17
T157
Q
A
V
R
K
S
S
T
V
A
T
L
Q
G
T
Site 18
T160
R
K
S
S
T
V
A
T
L
Q
G
T
P
D
H
Site 19
T164
T
V
A
T
L
Q
G
T
P
D
H
G
D
P
R
Site 20
T172
P
D
H
G
D
P
R
T
P
G
P
P
R
S
T
Site 21
S178
R
T
P
G
P
P
R
S
T
P
L
E
E
N
V
Site 22
T179
T
P
G
P
P
R
S
T
P
L
E
E
N
V
V
Site 23
S202
A
A
R
Q
Q
F
L
S
L
E
Q
A
N
K
G
Site 24
S213
A
N
K
G
A
P
H
S
S
P
A
R
G
T
P
Site 25
S214
N
K
G
A
P
H
S
S
P
A
R
G
T
P
A
Site 26
T219
H
S
S
P
A
R
G
T
P
A
G
T
T
P
G
Site 27
T224
R
G
T
P
A
G
T
T
P
G
A
S
Q
A
P
Site 28
S228
A
G
T
T
P
G
A
S
Q
A
P
K
A
F
N
Site 29
S278
Q
V
V
D
D
P
G
S
L
A
S
V
E
S
P
Site 30
S281
D
D
P
G
S
L
A
S
V
E
S
P
G
T
P
Site 31
S284
G
S
L
A
S
V
E
S
P
G
T
P
K
E
T
Site 32
T287
A
S
V
E
S
P
G
T
P
K
E
T
P
I
E
Site 33
T291
S
P
G
T
P
K
E
T
P
I
E
R
E
I
R
Site 34
T317
Q
R
G
L
R
Q
A
T
D
H
Q
E
L
V
E
Site 35
T327
Q
E
L
V
E
I
P
T
R
P
L
L
T
K
L
Site 36
S335
R
P
L
L
T
K
L
S
L
I
T
A
P
R
R
Site 37
T338
L
T
K
L
S
L
I
T
A
P
R
R
E
R
G
Site 38
S348
R
R
E
R
G
R
P
S
L
Y
V
Q
R
D
I
Site 39
Y350
E
R
G
R
P
S
L
Y
V
Q
R
D
I
V
Q
Site 40
T359
Q
R
D
I
V
Q
E
T
Q
R
E
E
D
H
R
Site 41
S376
G
L
H
V
G
R
A
S
T
P
D
W
V
S
E
Site 42
T377
L
H
V
G
R
A
S
T
P
D
W
V
S
E
G
Site 43
S382
A
S
T
P
D
W
V
S
E
G
P
Q
P
G
L
Site 44
S394
P
G
L
R
R
A
L
S
S
D
S
I
L
S
P
Site 45
S395
G
L
R
R
A
L
S
S
D
S
I
L
S
P
A
Site 46
S397
R
R
A
L
S
S
D
S
I
L
S
P
A
P
D
Site 47
S400
L
S
S
D
S
I
L
S
P
A
P
D
A
R
A
Site 48
Y425
N
R
I
P
P
D
A
Y
Q
P
Y
L
S
P
G
Site 49
Y428
P
P
D
A
Y
Q
P
Y
L
S
P
G
T
P
Q
Site 50
S430
D
A
Y
Q
P
Y
L
S
P
G
T
P
Q
L
E
Site 51
T433
Q
P
Y
L
S
P
G
T
P
Q
L
E
F
S
A
Site 52
S439
G
T
P
Q
L
E
F
S
A
F
G
A
F
G
K
Site 53
S448
F
G
A
F
G
K
P
S
S
L
S
T
A
E
A
Site 54
S449
G
A
F
G
K
P
S
S
L
S
T
A
E
A
K
Site 55
T452
G
K
P
S
S
L
S
T
A
E
A
K
A
A
T
Site 56
T459
T
A
E
A
K
A
A
T
S
P
K
A
T
M
S
Site 57
S460
A
E
A
K
A
A
T
S
P
K
A
T
M
S
P
Site 58
T464
A
A
T
S
P
K
A
T
M
S
P
R
H
L
S
Site 59
S466
T
S
P
K
A
T
M
S
P
R
H
L
S
E
S
Site 60
S471
T
M
S
P
R
H
L
S
E
S
S
G
K
P
L
Site 61
S473
S
P
R
H
L
S
E
S
S
G
K
P
L
S
T
Site 62
S474
P
R
H
L
S
E
S
S
G
K
P
L
S
T
K
Site 63
S479
E
S
S
G
K
P
L
S
T
K
Q
E
A
S
K
Site 64
S485
L
S
T
K
Q
E
A
S
K
P
P
R
G
C
P
Site 65
Y503
R
G
V
V
R
W
E
Y
F
R
L
R
P
L
R
Site 66
S541
P
A
L
R
L
Q
K
S
Q
S
S
D
L
L
E
Site 67
S543
L
R
L
Q
K
S
Q
S
S
D
L
L
E
R
E
Site 68
S544
R
L
Q
K
S
Q
S
S
D
L
L
E
R
E
R
Site 69
S553
L
L
E
R
E
R
E
S
V
L
R
R
E
Q
E
Site 70
S575
A
L
F
P
E
V
F
S
P
T
P
D
E
N
S
Site 71
T577
F
P
E
V
F
S
P
T
P
D
E
N
S
D
Q
Site 72
S582
S
P
T
P
D
E
N
S
D
Q
N
S
R
S
S
Site 73
S586
D
E
N
S
D
Q
N
S
R
S
S
S
Q
A
S
Site 74
S588
N
S
D
Q
N
S
R
S
S
S
Q
A
S
G
I
Site 75
S589
S
D
Q
N
S
R
S
S
S
Q
A
S
G
I
T
Site 76
S590
D
Q
N
S
R
S
S
S
Q
A
S
G
I
T
G
Site 77
S593
S
R
S
S
S
Q
A
S
G
I
T
G
S
Y
S
Site 78
T596
S
S
Q
A
S
G
I
T
G
S
Y
S
V
S
E
Site 79
S598
Q
A
S
G
I
T
G
S
Y
S
V
S
E
S
P
Site 80
S600
S
G
I
T
G
S
Y
S
V
S
E
S
P
F
F
Site 81
S602
I
T
G
S
Y
S
V
S
E
S
P
F
F
S
P
Site 82
S604
G
S
Y
S
V
S
E
S
P
F
F
S
P
I
H
Site 83
S608
V
S
E
S
P
F
F
S
P
I
H
L
H
S
N
Site 84
S626
T
V
E
D
P
V
D
S
A
P
P
G
Q
R
K
Site 85
Y638
Q
R
K
K
E
Q
W
Y
A
G
I
N
P
S
D
Site 86
S644
W
Y
A
G
I
N
P
S
D
G
I
N
S
E
V
Site 87
T658
V
L
E
A
I
R
V
T
R
H
K
N
A
M
A
Site 88
S670
A
M
A
E
R
W
E
S
R
I
Y
A
S
E
E
Site 89
Y673
E
R
W
E
S
R
I
Y
A
S
E
E
D
D
_
Site 90
S675
W
E
S
R
I
Y
A
S
E
E
D
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation