PhosphoNET

           
Protein Info 
   
Short Name:  Pim3
Full Name:  Serine/threonine-protein kinase pim-3
Alias:  EC 2.7.11.1; Pim-3 oncogene
Type:  Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CAMK group; PIM family
Mass (Da):  35891
Number AA:  326
UniProt ID:  Q86V86
International Prot ID:  IPI00384276
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005515  GO:0004674 PhosphoSite+ KinaseNET
Biological Process:  GO:0043066  GO:0006468  GO:0007346 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S35PAKADKESFEKAYQV
Site 2Y55SGGFGTVYAGSRIAD
Site 3T77HVVKERVTEWGSLGG
Site 4S81ERVTEWGSLGGATVP
Site 5T86WGSLGGATVPLEVVL
Site 6T137QDLFDFITERGALDE
Site 7S192LKLIDFGSGALLKDT
Site 8T199SGALLKDTVYTDFDG
Site 9Y201ALLKDTVYTDFDGTR
Site 10T202LLKDTVYTDFDGTRV
Site 11T207VYTDFDGTRVYSPPE
Site 12Y210DFDGTRVYSPPEWIR
Site 13S211FDGTRVYSPPEWIRY
Site 14Y218SPPEWIRYHRYHGRS
Site 15Y221EWIRYHRYHGRSATV
Site 16T227RYHGRSATVWSLGVL
Site 17S263LLFRRRVSPECQQLI
Site 18S275QLIRWCLSLRPSERP
Site 19S279WCLSLRPSERPSLDQ
Site 20S283LRPSERPSLDQIAAH
Site 21S303ADGGVPESCDLRLCT
Site 22T310SCDLRLCTLDPDDVA
Site 23S318LDPDDVASTTSSSES
Site 24T319DPDDVASTTSSSESL
Site 25T320PDDVASTTSSSESL_
Site 26S321DDVASTTSSSESL__
Site 27S322DVASTTSSSESL___
Site 28S323VASTTSSSESL____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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