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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCNK18
Full Name:
Potassium channel subfamily K member 18
Alias:
KCNKI
Type:
Ion channel, ligand-gated, potassium
Mass (Da):
43671
Number AA:
384
UniProt ID:
Q7Z418
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0030955
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S72
L
C
R
I
L
N
C
S
E
T
V
V
E
D
R
Site 2
T74
R
I
L
N
C
S
E
T
V
V
E
D
R
K
Q
Site 3
Y123
T
V
G
Y
G
Y
I
Y
P
V
T
R
L
G
K
Site 4
Y131
P
V
T
R
L
G
K
Y
L
C
M
L
Y
A
L
Site 5
Y136
G
K
Y
L
C
M
L
Y
A
L
F
G
I
P
L
Site 6
S160
D
I
L
A
T
I
L
S
T
S
Y
N
R
F
R
Site 7
S162
L
A
T
I
L
S
T
S
Y
N
R
F
R
K
F
Site 8
Y163
A
T
I
L
S
T
S
Y
N
R
F
R
K
F
P
Site 9
T173
F
R
K
F
P
F
F
T
R
P
L
L
S
K
W
Site 10
S178
F
F
T
R
P
L
L
S
K
W
C
P
K
S
L
Site 11
S184
L
S
K
W
C
P
K
S
L
F
K
K
K
P
D
Site 12
S205
A
V
P
Q
I
I
I
S
A
E
E
L
P
G
P
Site 13
T216
L
P
G
P
K
L
G
T
C
P
S
R
P
S
C
Site 14
S219
P
K
L
G
T
C
P
S
R
P
S
C
S
M
E
Site 15
S222
G
T
C
P
S
R
P
S
C
S
M
E
L
F
E
Site 16
S224
C
P
S
R
P
S
C
S
M
E
L
F
E
R
S
Site 17
T239
H
A
L
E
K
Q
N
T
L
Q
L
P
P
Q
A
Site 18
S250
P
P
Q
A
M
E
R
S
N
S
C
P
E
L
V
Site 19
S252
Q
A
M
E
R
S
N
S
C
P
E
L
V
L
G
Site 20
S262
E
L
V
L
G
R
L
S
Y
S
I
I
S
N
L
Site 21
S264
V
L
G
R
L
S
Y
S
I
I
S
N
L
D
E
Site 22
S267
R
L
S
Y
S
I
I
S
N
L
D
E
V
G
Q
Site 23
T329
T
T
I
G
F
G
D
T
V
L
E
H
P
N
F
Site 24
Y379
F
F
A
K
G
K
F
Y
H
L
V
K
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation