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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTR9
Full Name:
RNA polymerase-associated protein CTR9 homolog
Alias:
SH2 domain-binding protein 1
Type:
Transcription regulation
Mass (Da):
133502
Number AA:
1173
UniProt ID:
Q6PD62
International Prot ID:
IPI00477468
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016593
GO:0016607
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0042169
PhosphoSite+
KinaseNET
Biological Process:
GO:0033523
GO:0010390
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
S
R
G
S
I
E
I
P
L
R
D
Site 2
T13
I
E
I
P
L
R
D
T
D
E
V
I
E
L
D
Site 3
T39
S
I
L
K
Q
E
H
T
Q
L
H
I
W
I
A
Site 4
Y75
R
I
D
G
N
L
D
Y
R
D
H
E
K
D
Q
Site 5
T84
D
H
E
K
D
Q
M
T
C
L
D
T
L
A
A
Site 6
Y92
C
L
D
T
L
A
A
Y
Y
V
Q
Q
A
R
K
Site 7
Y93
L
D
T
L
A
A
Y
Y
V
Q
Q
A
R
K
E
Site 8
T111
D
N
K
K
D
L
I
T
Q
A
T
L
L
Y
T
Site 9
T114
K
D
L
I
T
Q
A
T
L
L
Y
T
M
A
D
Site 10
Y117
I
T
Q
A
T
L
L
Y
T
M
A
D
K
I
I
Site 11
T118
T
Q
A
T
L
L
Y
T
M
A
D
K
I
I
M
Site 12
Y126
M
A
D
K
I
I
M
Y
D
Q
N
H
L
L
G
Site 13
S173
L
L
G
K
A
C
I
S
F
N
K
K
D
Y
R
Site 14
Y179
I
S
F
N
K
K
D
Y
R
G
A
L
A
Y
Y
Site 15
Y185
D
Y
R
G
A
L
A
Y
Y
K
K
A
L
R
T
Site 16
S222
E
K
A
R
L
A
F
S
R
A
L
E
L
N
S
Site 17
S259
K
N
G
V
Q
L
L
S
R
A
Y
T
I
D
P
Site 18
Y262
V
Q
L
L
S
R
A
Y
T
I
D
P
S
N
P
Site 19
T263
Q
L
L
S
R
A
Y
T
I
D
P
S
N
P
M
Site 20
Y285
H
F
F
F
K
K
D
Y
S
K
V
Q
H
L
A
Site 21
Y322
S
F
H
V
Q
E
D
Y
D
Q
A
F
Q
Y
Y
Site 22
Y328
D
Y
D
Q
A
F
Q
Y
Y
Y
Q
A
T
Q
F
Site 23
Y330
D
Q
A
F
Q
Y
Y
Y
Q
A
T
Q
F
A
S
Site 24
Y351
F
F
G
L
G
Q
M
Y
I
Y
R
G
D
K
E
Site 25
S361
R
G
D
K
E
N
A
S
Q
C
F
E
K
V
L
Site 26
Y371
F
E
K
V
L
K
A
Y
P
N
N
Y
E
T
M
Site 27
S383
E
T
M
K
I
L
G
S
L
Y
A
A
S
E
D
Site 28
Y385
M
K
I
L
G
S
L
Y
A
A
S
E
D
Q
E
Site 29
Y408
L
K
K
V
T
E
Q
Y
P
D
D
V
E
A
W
Site 30
S432
T
D
I
Q
G
A
L
S
A
Y
G
T
A
T
R
Site 31
Y473
N
L
G
E
A
K
K
Y
F
L
A
S
L
D
R
Site 32
S477
A
K
K
Y
F
L
A
S
L
D
R
A
K
A
E
Site 33
Y491
E
A
E
H
D
E
H
Y
Y
N
A
I
S
V
T
Site 34
Y492
A
E
H
D
E
H
Y
Y
N
A
I
S
V
T
T
Site 35
Y507
S
Y
N
L
A
R
L
Y
E
A
M
C
E
F
H
Site 36
Y530
I
L
R
E
H
P
N
Y
V
D
C
Y
L
R
L
Site 37
Y534
H
P
N
Y
V
D
C
Y
L
R
L
G
A
M
A
Site 38
Y548
A
R
D
K
G
N
F
Y
E
A
S
D
W
F
K
Site 39
S596
E
R
I
L
K
Q
P
S
T
Q
S
D
T
Y
S
Site 40
T597
R
I
L
K
Q
P
S
T
Q
S
D
T
Y
S
M
Site 41
S599
L
K
Q
P
S
T
Q
S
D
T
Y
S
M
L
A
Site 42
T601
Q
P
S
T
Q
S
D
T
Y
S
M
L
A
L
G
Site 43
Y602
P
S
T
Q
S
D
T
Y
S
M
L
A
L
G
N
Site 44
S603
S
T
Q
S
D
T
Y
S
M
L
A
L
G
N
V
Site 45
Y636
Q
D
R
A
L
A
I
Y
K
Q
V
L
R
N
D
Site 46
Y648
R
N
D
A
K
N
L
Y
A
A
N
G
I
G
A
Site 47
Y662
A
V
L
A
H
K
G
Y
F
R
E
A
R
D
V
Site 48
T677
F
A
Q
V
R
E
A
T
A
D
I
S
D
V
W
Site 49
S681
R
E
A
T
A
D
I
S
D
V
W
L
N
L
A
Site 50
Y691
W
L
N
L
A
H
I
Y
V
E
Q
K
Q
Y
I
Site 51
Y697
I
Y
V
E
Q
K
Q
Y
I
S
A
V
Q
M
Y
Site 52
Y712
E
N
C
L
R
K
F
Y
K
H
Q
N
T
E
V
Site 53
T739
K
L
Q
E
C
K
Q
T
L
L
K
A
R
H
V
Site 54
S749
K
A
R
H
V
A
P
S
D
T
V
L
M
F
N
Site 55
T766
L
V
L
Q
R
L
A
T
S
V
L
K
D
E
K
Site 56
S774
S
V
L
K
D
E
K
S
N
L
K
E
V
L
N
Site 57
Y792
E
L
E
L
A
H
R
Y
F
S
Y
L
S
K
V
Site 58
S794
E
L
A
H
R
Y
F
S
Y
L
S
K
V
G
D
Site 59
Y795
L
A
H
R
Y
F
S
Y
L
S
K
V
G
D
K
Site 60
S797
H
R
Y
F
S
Y
L
S
K
V
G
D
K
M
R
Site 61
T812
F
D
L
A
L
A
A
T
E
A
R
Q
C
S
D
Site 62
S818
A
T
E
A
R
Q
C
S
D
L
L
S
Q
A
Q
Site 63
S822
R
Q
C
S
D
L
L
S
Q
A
Q
Y
H
V
A
Site 64
Y826
D
L
L
S
Q
A
Q
Y
H
V
A
R
A
R
K
Site 65
Y881
L
L
E
Q
R
A
Q
Y
V
E
K
T
K
N
I
Site 66
T892
T
K
N
I
L
M
F
T
G
E
T
E
A
T
K
Site 67
T898
F
T
G
E
T
E
A
T
K
E
K
K
R
G
G
Site 68
S911
G
G
G
G
G
R
R
S
K
K
G
G
E
F
D
Site 69
T925
D
E
F
V
N
D
D
T
D
D
D
L
P
I
S
Site 70
S932
T
D
D
D
L
P
I
S
K
K
K
K
R
R
K
Site 71
S941
K
K
K
R
R
K
G
S
G
S
E
Q
E
G
E
Site 72
S943
K
R
R
K
G
S
G
S
E
Q
E
G
E
D
E
Site 73
S970
H
P
K
G
E
E
G
S
D
D
D
E
T
E
N
Site 74
T975
E
G
S
D
D
D
E
T
E
N
G
P
K
P
K
Site 75
S1003
K
P
E
R
L
P
P
S
M
K
G
K
I
K
S
Site 76
S1010
S
M
K
G
K
I
K
S
K
A
I
I
S
S
S
Site 77
S1015
I
K
S
K
A
I
I
S
S
S
D
D
S
S
D
Site 78
S1016
K
S
K
A
I
I
S
S
S
D
D
S
S
D
E
Site 79
S1017
S
K
A
I
I
S
S
S
D
D
S
S
D
E
D
Site 80
S1020
I
I
S
S
S
D
D
S
S
D
E
D
K
L
K
Site 81
S1021
I
S
S
S
D
D
S
S
D
E
D
K
L
K
I
Site 82
S1037
D
E
G
H
P
R
N
S
N
S
N
S
D
S
D
Site 83
S1039
G
H
P
R
N
S
N
S
N
S
D
S
D
E
D
Site 84
S1041
P
R
N
S
N
S
N
S
D
S
D
E
D
E
Q
Site 85
S1043
N
S
N
S
N
S
D
S
D
E
D
E
Q
R
K
Site 86
S1054
E
Q
R
K
K
C
A
S
S
E
S
D
S
D
E
Site 87
S1055
Q
R
K
K
C
A
S
S
E
S
D
S
D
E
N
Site 88
S1057
K
K
C
A
S
S
E
S
D
S
D
E
N
Q
N
Site 89
S1059
C
A
S
S
E
S
D
S
D
E
N
Q
N
K
S
Site 90
S1066
S
D
E
N
Q
N
K
S
G
S
E
A
G
S
P
Site 91
S1068
E
N
Q
N
K
S
G
S
E
A
G
S
P
R
R
Site 92
S1072
K
S
G
S
E
A
G
S
P
R
R
P
R
R
Q
Site 93
S1081
R
R
P
R
R
Q
R
S
D
Q
D
S
D
S
D
Site 94
S1085
R
Q
R
S
D
Q
D
S
D
S
D
Q
P
S
R
Site 95
S1087
R
S
D
Q
D
S
D
S
D
Q
P
S
R
K
R
Site 96
S1091
D
S
D
S
D
Q
P
S
R
K
R
R
P
S
G
Site 97
S1097
P
S
R
K
R
R
P
S
G
S
E
Q
S
D
N
Site 98
S1099
R
K
R
R
P
S
G
S
E
Q
S
D
N
E
S
Site 99
S1102
R
P
S
G
S
E
Q
S
D
N
E
S
V
Q
S
Site 100
S1106
S
E
Q
S
D
N
E
S
V
Q
S
G
R
S
H
Site 101
S1109
S
D
N
E
S
V
Q
S
G
R
S
H
S
G
V
Site 102
S1112
E
S
V
Q
S
G
R
S
H
S
G
V
S
E
N
Site 103
S1114
V
Q
S
G
R
S
H
S
G
V
S
E
N
D
S
Site 104
S1117
G
R
S
H
S
G
V
S
E
N
D
S
R
P
A
Site 105
S1121
S
G
V
S
E
N
D
S
R
P
A
S
P
S
A
Site 106
S1125
E
N
D
S
R
P
A
S
P
S
A
E
S
D
H
Site 107
S1127
D
S
R
P
A
S
P
S
A
E
S
D
H
E
S
Site 108
S1130
P
A
S
P
S
A
E
S
D
H
E
S
E
R
G
Site 109
S1134
S
A
E
S
D
H
E
S
E
R
G
S
D
N
E
Site 110
S1138
D
H
E
S
E
R
G
S
D
N
E
G
S
G
Q
Site 111
S1143
R
G
S
D
N
E
G
S
G
Q
G
S
G
N
E
Site 112
S1147
N
E
G
S
G
Q
G
S
G
N
E
S
E
P
E
Site 113
S1151
G
Q
G
S
G
N
E
S
E
P
E
G
S
N
N
Site 114
S1156
N
E
S
E
P
E
G
S
N
N
E
A
S
D
R
Site 115
S1161
E
G
S
N
N
E
A
S
D
R
G
S
E
H
G
Site 116
S1165
N
E
A
S
D
R
G
S
E
H
G
S
D
D
S
Site 117
S1169
D
R
G
S
E
H
G
S
D
D
S
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation