PhosphoNET

           
Protein Info 
   
Short Name:  CEP170
Full Name:  Centrosomal protein of 170 kDa
Alias:  CE170; Centrosomal protein 170kDa; FAM68A; KAB; KARP 1 binding protein; KARP-1-binding protein; KARP1-binding protein 1; KARP-1-binding protein 1; KIAA0470; XRCC5 binding protein
Type:  Microtubule binding protein, Cell cycle protein
Mass (Da):  175293
Number AA:  1584
UniProt ID:  Q5SW79
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005814  GO:0005874  GO:0005819 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T4____MSLTSWFLVSS
Site 2S5___MSLTSWFLVSSG
Site 3S10LTSWFLVSSGGTRHR
Site 4S11TSWFLVSSGGTRHRL
Site 5S38ELMLQSRSVDKQHAV
Site 6S51AVINYDASTDEHLVK
Site 7S62HLVKDLGSLNGTFVN
Site 8Y91EDKLRFGYDTNLFTV
Site 9T93KLRFGYDTNLFTVVQ
Site 10T97GYDTNLFTVVQGEMR
Site 11S122FTIQLQLSQKSSESE
Site 12S125QLQLSQKSSESELSK
Site 13S126LQLSQKSSESELSKS
Site 14S128LSQKSSESELSKSAS
Site 15S131KSSESELSKSASAKS
Site 16S133SESELSKSASAKSID
Site 17S135SELSKSASAKSIDSK
Site 18S138SKSASAKSIDSKVAD
Site 19S141ASAKSIDSKVADAAT
Site 20T154ATEVQHKTTEALKSE
Site 21S160KTTEALKSEEKAMDI
Site 22S168EEKAMDISAMPRGTP
Site 23T174ISAMPRGTPLYGQPS
Site 24Y177MPRGTPLYGQPSWWG
Site 25S181TPLYGQPSWWGDDEV
Site 26S210KNHEAGTSGCGIDAK
Site 27S239FPFCREPSYFEIPTK
Site 28Y240PFCREPSYFEIPTKE
Site 29S252TKEFQQPSQITESTI
Site 30T267HEIPTKDTPSSHITG
Site 31S269IPTKDTPSSHITGAG
Site 32S270PTKDTPSSHITGAGH
Site 33T273DTPSSHITGAGHASF
Site 34S287FTIEFDDSTPGKVTI
Site 35T288TIEFDDSTPGKVTIR
Site 36T299VTIRDHVTKFTSDQR
Site 37S309TSDQRHKSKKSSPGT
Site 38S312QRHKSKKSSPGTQDL
Site 39S313RHKSKKSSPGTQDLL
Site 40T316SKKSSPGTQDLLGIQ
Site 41T350PQMLWERTEEDSKSI
Site 42S354WERTEEDSKSIKSDV
Site 43S356RTEEDSKSIKSDVPV
Site 44S359EDSKSIKSDVPVYLK
Site 45Y364IKSDVPVYLKRLKGN
Site 46T377GNKHDDGTQSDSENA
Site 47S379KHDDGTQSDSENAGA
Site 48S381DDGTQSDSENAGAHR
Site 49S391AGAHRRCSKRATLEE
Site 50T395RRCSKRATLEEHLRR
Site 51S405EHLRRHHSEHKKLQK
Site 52S427QDQAVTSSAHHRGGH
Site 53S446GKLLKQKSEEPSVSI
Site 54S450KQKSEEPSVSIPFLQ
Site 55S452KSEEPSVSIPFLQTA
Site 56S463LQTALLRSSGSLGHR
Site 57S464QTALLRSSGSLGHRP
Site 58S466ALLRSSGSLGHRPSQ
Site 59S472GSLGHRPSQEMDKML
Site 60T484KMLKNQATSATSEKD
Site 61S497KDNDDDQSDKGTYTI
Site 62T501DDQSDKGTYTIELEN
Site 63Y502DQSDKGTYTIELENP
Site 64T503QSDKGTYTIELENPN
Site 65S511IELENPNSEEVEARK
Site 66Y532GVDDNQDYNRPVINE
Site 67T564MEERKPLTTSGFHHS
Site 68T565EERKPLTTSGFHHSE
Site 69S566ERKPLTTSGFHHSEE
Site 70S571TTSGFHHSEEGTSSS
Site 71T575FHHSEEGTSSSGSKR
Site 72S576HHSEEGTSSSGSKRW
Site 73S577HSEEGTSSSGSKRWV
Site 74S578SEEGTSSSGSKRWVS
Site 75S580EGTSSSGSKRWVSQW
Site 76S585SGSKRWVSQWASLAA
Site 77S607EERIMEFSAPLPLEN
Site 78S619LENETEISESGMTVR
Site 79S621NETEISESGMTVRST
Site 80T624EISESGMTVRSTGSA
Site 81S627ESGMTVRSTGSATSL
Site 82T628SGMTVRSTGSATSLA
Site 83S630MTVRSTGSATSLASQ
Site 84T632VRSTGSATSLASQGE
Site 85S633RSTGSATSLASQGER
Site 86S636GSATSLASQGERRRR
Site 87T644QGERRRRTLPQLPNE
Site 88S654QLPNEEKSLESHRAK
Site 89T664SHRAKVVTQRSEIGE
Site 90S667AKVVTQRSEIGEKQD
Site 91T675EIGEKQDTELQEKET
Site 92T682TELQEKETPTQVYQK
Site 93S699QDADRPLSKMNRAVN
Site 94T712VNGETLKTGGDNKTL
Site 95T718KTGGDNKTLLHLGSS
Site 96S724KTLLHLGSSAPGKEK
Site 97S725TLLHLGSSAPGKEKS
Site 98S732SAPGKEKSETDKETS
Site 99T734PGKEKSETDKETSLV
Site 100S739SETDKETSLVKQTLA
Site 101T760QREEAQWTPTKLSSK
Site 102S766WTPTKLSSKNVSGQT
Site 103S770KLSSKNVSGQTDKCR
Site 104T780TDKCREETFKQESQP
Site 105S785EETFKQESQPPEKNS
Site 106S792SQPPEKNSGHSTSKG
Site 107T796EKNSGHSTSKGDRVA
Site 108S807DRVAQSESKRRKAEE
Site 109S818KAEEILKSQTPKGGD
Site 110T820EEILKSQTPKGGDKK
Site 111S830GGDKKESSKSLVRQG
Site 112S832DKKESSKSLVRQGSF
Site 113S838KSLVRQGSFTIEKPS
Site 114T840LVRQGSFTIEKPSPN
Site 115S845SFTIEKPSPNIPIEL
Site 116S861PHINKQTSSTPSSLA
Site 117S862HINKQTSSTPSSLAL
Site 118T863INKQTSSTPSSLALT
Site 119S865KQTSSTPSSLALTSA
Site 120S866QTSSTPSSLALTSAS
Site 121T870TPSSLALTSASRIRE
Site 122S871PSSLALTSASRIRER
Site 123S873SLALTSASRIRERSE
Site 124S879ASRIRERSESLDPDS
Site 125S881RIRERSESLDPDSSM
Site 126S886SESLDPDSSMDTTLI
Site 127S887ESLDPDSSMDTTLIL
Site 128T890DPDSSMDTTLILKDT
Site 129T891PDSSMDTTLILKDTE
Site 130T914KLREDNKTDEGPDTP
Site 131T920KTDEGPDTPSYNRDN
Site 132S922DEGPDTPSYNRDNSI
Site 133Y923EGPDTPSYNRDNSIS
Site 134S928PSYNRDNSISPESDV
Site 135S930YNRDNSISPESDVDT
Site 136S933DNSISPESDVDTAST
Site 137T937SPESDVDTASTISLV
Site 138S939ESDVDTASTISLVTG
Site 139T948ISLVTGETERKSTQK
Site 140S952TGETERKSTQKRKSF
Site 141T953GETERKSTQKRKSFT
Site 142S958KSTQKRKSFTSLYKD
Site 143T960TQKRKSFTSLYKDRC
Site 144S961QKRKSFTSLYKDRCS
Site 145Y963RKSFTSLYKDRCSTG
Site 146S968SLYKDRCSTGSPSKD
Site 147T969LYKDRCSTGSPSKDV
Site 148S971KDRCSTGSPSKDVTK
Site 149S973RCSTGSPSKDVTKSS
Site 150T977GSPSKDVTKSSSSGA
Site 151S979PSKDVTKSSSSGARE
Site 152S982DVTKSSSSGAREKME
Site 153T992REKMEKKTKSRSTDV
Site 154S994KMEKKTKSRSTDVGS
Site 155S996EKKTKSRSTDVGSRA
Site 156T997KKTKSRSTDVGSRAD
Site 157S1001SRSTDVGSRADGRKF
Site 158S1011DGRKFVQSSGRIRQP
Site 159S1012GRKFVQSSGRIRQPS
Site 160S1019SGRIRQPSVDLTDDD
Site 161T1023RQPSVDLTDDDQTSS
Site 162T1028DLTDDDQTSSVPHSA
Site 163S1029LTDDDQTSSVPHSAI
Site 164S1030TDDDQTSSVPHSAIS
Site 165S1034QTSSVPHSAISDIMS
Site 166S1037SVPHSAISDIMSSDQ
Site 167S1041SAISDIMSSDQETYS
Site 168S1042AISDIMSSDQETYSC
Site 169T1046IMSSDQETYSCKPHG
Site 170Y1047MSSDQETYSCKPHGR
Site 171S1048SSDQETYSCKPHGRT
Site 172T1055SCKPHGRTPLTSADE
Site 173T1058PHGRTPLTSADEHVH
Site 174S1059HGRTPLTSADEHVHS
Site 175S1066SADEHVHSKLEGSKV
Site 176S1076EGSKVTKSKTSPVVS
Site 177T1078SKVTKSKTSPVVSGS
Site 178S1079KVTKSKTSPVVSGSS
Site 179S1083SKTSPVVSGSSSKST
Site 180S1085TSPVVSGSSSKSTTL
Site 181S1086SPVVSGSSSKSTTLP
Site 182S1087PVVSGSSSKSTTLPR
Site 183S1089VSGSSSKSTTLPRPR
Site 184T1090SGSSSKSTTLPRPRP
Site 185T1091GSSSKSTTLPRPRPT
Site 186T1098TLPRPRPTRTSLLRR
Site 187S1101RPRPTRTSLLRRARL
Site 188S1112RARLGEASDSELADA
Site 189S1114RLGEASDSELADADK
Site 190S1123LADADKASVASEVST
Site 191S1126ADKASVASEVSTTSS
Site 192S1129ASVASEVSTTSSTSK
Site 193T1130SVASEVSTTSSTSKP
Site 194T1131VASEVSTTSSTSKPP
Site 195S1132ASEVSTTSSTSKPPT
Site 196S1133SEVSTTSSTSKPPTG
Site 197S1135VSTTSSTSKPPTGRR
Site 198T1139SSTSKPPTGRRNISR
Site 199S1145PTGRRNISRIDLLAQ
Site 200T1156LLAQPRRTRLGSLSA
Site 201S1160PRRTRLGSLSARSDS
Site 202S1162RTRLGSLSARSDSEA
Site 203S1165LGSLSARSDSEATIS
Site 204S1167SLSARSDSEATISRS
Site 205T1170ARSDSEATISRSSAS
Site 206S1172SDSEATISRSSASSR
Site 207S1174SEATISRSSASSRTA
Site 208S1175EATISRSSASSRTAE
Site 209S1177TISRSSASSRTAEAI
Site 210S1178ISRSSASSRTAEAII
Site 211S1194SGARLVPSDKFSPRI
Site 212S1198LVPSDKFSPRIRANS
Site 213S1205SPRIRANSISRLSDS
Site 214S1207RIRANSISRLSDSKV
Site 215S1210ANSISRLSDSKVKSM
Site 216S1212SISRLSDSKVKSMTS
Site 217S1216LSDSKVKSMTSAHGS
Site 218S1219SKVKSMTSAHGSASV
Site 219S1223SMTSAHGSASVNSRW
Site 220S1225TSAHGSASVNSRWRR
Site 221S1228HGSASVNSRWRRFPT
Site 222T1235SRWRRFPTDYASTSE
Site 223Y1237WRRFPTDYASTSEDE
Site 224S1239RFPTDYASTSEDEFG
Site 225T1240FPTDYASTSEDEFGS
Site 226S1241PTDYASTSEDEFGSN
Site 227S1247TSEDEFGSNRNSPKH
Site 228S1251EFGSNRNSPKHTRLR
Site 229T1255NRNSPKHTRLRTSPA
Site 230T1259PKHTRLRTSPALKTT
Site 231S1260KHTRLRTSPALKTTR
Site 232T1265RTSPALKTTRLQSAG
Site 233S1270LKTTRLQSAGSAMPT
Site 234S1273TRLQSAGSAMPTSSS
Site 235T1277SAGSAMPTSSSFKHR
Site 236S1278AGSAMPTSSSFKHRI
Site 237S1279GSAMPTSSSFKHRIK
Site 238S1280SAMPTSSSFKHRIKE
Site 239Y1291RIKEQEDYIRDWTAH
Site 240T1296EDYIRDWTAHREEIA
Site 241S1306REEIARISQDLALIA
Site 242S1325DVAGEIDSVTSSGTA
Site 243T1327AGEIDSVTSSGTAPS
Site 244S1329EIDSVTSSGTAPSTT
Site 245S1334TSSGTAPSTTVSTAA
Site 246T1335SSGTAPSTTVSTAAT
Site 247T1336SGTAPSTTVSTAATT
Site 248S1338TAPSTTVSTAATTPG
Site 249T1350TPGSAIDTREELVDR
Site 250S1362VDRVFDESLNFRKIP
Site 251S1374KIPPLVHSKTPEGNN
Site 252T1376PPLVHSKTPEGNNGR
Site 253S1384PEGNNGRSGDPRPQA
Site 254T1399AEPPDHLTITRRRTW
Site 255T1401PPDHLTITRRRTWSR
Site 256T1405LTITRRRTWSRDEVM
Site 257S1407ITRRRTWSRDEVMGD
Site 258S1420GDNLLLSSVFQFSKK
Site 259S1431FSKKIRQSIDKTAGK
Site 260T1435IRQSIDKTAGKIRIL
Site 261S1455RNWDDIESKLRAESE
Site 262S1461ESKLRAESEVPIVKT
Site 263T1468SEVPIVKTSSMEISS
Site 264S1474KTSSMEISSILQELK
Site 265S1475TSSMEISSILQELKR
Site 266T1499AMIDPDGTLEALNNM
Site 267S1510LNNMGFPSAMLPSPP
Site 268S1515FPSAMLPSPPKQKSS
Site 269S1521PSPPKQKSSPVNNHH
Site 270S1522SPPKQKSSPVNNHHS
Site 271S1529SPVNNHHSPGQTPTL
Site 272T1533NHHSPGQTPTLGQPE
Site 273S1560AEFENAESEADFSIH
Site 274S1565AESEADFSIHFNRFN
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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