KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TOR1AIP1
Full Name:
Torsin-1A-interacting protein 1
Alias:
FLJ13142; lamina associated polypeptide 1B; LAP1B; TOIP1; torsin A interacting protein 1; Torsin-1A-interacting protein 1: Torsin-1A-interacting protein 1
Type:
Structural protein, lamin binding
Mass (Da):
66248
Number AA:
583
UniProt ID:
Q5JTV8
International Prot ID:
IPI00645381
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
V
R
E
G
W
G
V
Y
V
T
P
R
A
P
I
Site 2
T20
E
G
W
G
V
Y
V
T
P
R
A
P
I
R
E
Site 3
Y45
G
S
S
D
A
P
A
Y
R
T
P
P
S
R
Q
Site 4
T47
S
D
A
P
A
Y
R
T
P
P
S
R
Q
G
R
Site 5
S50
P
A
Y
R
T
P
P
S
R
Q
G
R
R
E
V
Site 6
S60
G
R
R
E
V
R
F
S
D
E
P
P
E
V
Y
Site 7
Y67
S
D
E
P
P
E
V
Y
G
D
F
E
P
L
V
Site 8
S79
P
L
V
A
K
E
R
S
P
V
G
K
R
T
R
Site 9
S92
T
R
L
E
E
F
R
S
D
S
A
K
E
E
V
Site 10
S94
L
E
E
F
R
S
D
S
A
K
E
E
V
R
E
Site 11
S102
A
K
E
E
V
R
E
S
A
Y
Y
L
R
S
R
Site 12
Y104
E
E
V
R
E
S
A
Y
Y
L
R
S
R
Q
R
Site 13
Y105
E
V
R
E
S
A
Y
Y
L
R
S
R
Q
R
R
Site 14
T124
Q
E
T
E
E
M
K
T
R
R
T
T
R
L
Q
Site 15
T127
E
E
M
K
T
R
R
T
T
R
L
Q
Q
Q
H
Site 16
T128
E
M
K
T
R
R
T
T
R
L
Q
Q
Q
H
S
Site 17
S135
T
R
L
Q
Q
Q
H
S
E
Q
P
P
L
Q
P
Site 18
S143
E
Q
P
P
L
Q
P
S
P
V
M
T
R
R
G
Site 19
T147
L
Q
P
S
P
V
M
T
R
R
G
L
R
D
S
Site 20
S154
T
R
R
G
L
R
D
S
H
S
S
E
E
D
E
Site 21
S156
R
G
L
R
D
S
H
S
S
E
E
D
E
A
S
Site 22
S157
G
L
R
D
S
H
S
S
E
E
D
E
A
S
S
Site 23
S163
S
S
E
E
D
E
A
S
S
Q
T
D
L
S
Q
Site 24
S164
S
E
E
D
E
A
S
S
Q
T
D
L
S
Q
T
Site 25
T166
E
D
E
A
S
S
Q
T
D
L
S
Q
T
I
S
Site 26
S169
A
S
S
Q
T
D
L
S
Q
T
I
S
K
K
T
Site 27
T171
S
Q
T
D
L
S
Q
T
I
S
K
K
T
V
R
Site 28
S173
T
D
L
S
Q
T
I
S
K
K
T
V
R
S
I
Site 29
T176
S
Q
T
I
S
K
K
T
V
R
S
I
Q
E
A
Site 30
S179
I
S
K
K
T
V
R
S
I
Q
E
A
P
V
S
Site 31
S186
S
I
Q
E
A
P
V
S
E
D
L
V
I
R
L
Site 32
Y200
L
R
R
P
P
L
R
Y
P
R
Y
E
A
T
S
Site 33
Y203
P
P
L
R
Y
P
R
Y
E
A
T
S
V
Q
Q
Site 34
S207
Y
P
R
Y
E
A
T
S
V
Q
Q
K
V
N
F
Site 35
S215
V
Q
Q
K
V
N
F
S
E
E
G
E
T
E
E
Site 36
T220
N
F
S
E
E
G
E
T
E
E
D
D
Q
D
S
Site 37
S227
T
E
E
D
D
Q
D
S
S
H
S
S
V
T
T
Site 38
S228
E
E
D
D
Q
D
S
S
H
S
S
V
T
T
V
Site 39
S230
D
D
Q
D
S
S
H
S
S
V
T
T
V
K
A
Site 40
S231
D
Q
D
S
S
H
S
S
V
T
T
V
K
A
R
Site 41
T234
S
S
H
S
S
V
T
T
V
K
A
R
S
R
D
Site 42
S242
V
K
A
R
S
R
D
S
D
E
S
G
D
K
T
Site 43
S245
R
S
R
D
S
D
E
S
G
D
K
T
T
R
S
Site 44
T249
S
D
E
S
G
D
K
T
T
R
S
S
S
Q
Y
Site 45
T250
D
E
S
G
D
K
T
T
R
S
S
S
Q
Y
I
Site 46
S252
S
G
D
K
T
T
R
S
S
S
Q
Y
I
E
S
Site 47
S253
G
D
K
T
T
R
S
S
S
Q
Y
I
E
S
F
Site 48
S254
D
K
T
T
R
S
S
S
Q
Y
I
E
S
F
W
Site 49
Y256
T
T
R
S
S
S
Q
Y
I
E
S
F
W
Q
S
Site 50
S259
S
S
S
Q
Y
I
E
S
F
W
Q
S
S
Q
S
Site 51
S263
Y
I
E
S
F
W
Q
S
S
Q
S
Q
N
F
T
Site 52
S264
I
E
S
F
W
Q
S
S
Q
S
Q
N
F
T
A
Site 53
S266
S
F
W
Q
S
S
Q
S
Q
N
F
T
A
H
D
Site 54
T270
S
S
Q
S
Q
N
F
T
A
H
D
K
Q
P
S
Site 55
S277
T
A
H
D
K
Q
P
S
V
L
S
S
G
Y
Q
Site 56
S281
K
Q
P
S
V
L
S
S
G
Y
Q
K
T
P
Q
Site 57
T286
L
S
S
G
Y
Q
K
T
P
Q
E
W
A
P
Q
Site 58
T294
P
Q
E
W
A
P
Q
T
A
R
I
R
T
R
M
Site 59
T299
P
Q
T
A
R
I
R
T
R
M
Q
N
D
S
I
Site 60
S305
R
T
R
M
Q
N
D
S
I
L
K
S
E
L
G
Site 61
S309
Q
N
D
S
I
L
K
S
E
L
G
N
Q
S
P
Site 62
S315
K
S
E
L
G
N
Q
S
P
S
T
S
S
R
Q
Site 63
S317
E
L
G
N
Q
S
P
S
T
S
S
R
Q
V
T
Site 64
T318
L
G
N
Q
S
P
S
T
S
S
R
Q
V
T
G
Site 65
S319
G
N
Q
S
P
S
T
S
S
R
Q
V
T
G
Q
Site 66
T324
S
T
S
S
R
Q
V
T
G
Q
P
Q
N
A
S
Site 67
S331
T
G
Q
P
Q
N
A
S
F
V
K
R
N
R
W
Site 68
S356
S
G
S
F
W
F
F
S
T
P
E
V
E
T
T
Site 69
T357
G
S
F
W
F
F
S
T
P
E
V
E
T
T
A
Site 70
T363
S
T
P
E
V
E
T
T
A
V
Q
E
F
Q
N
Site 71
Y379
M
N
Q
L
K
N
K
Y
Q
G
Q
D
E
K
L
Site 72
T392
K
L
W
K
R
S
Q
T
F
L
E
K
H
L
N
Site 73
S400
F
L
E
K
H
L
N
S
S
H
P
R
S
Q
P
Site 74
S401
L
E
K
H
L
N
S
S
H
P
R
S
Q
P
A
Site 75
S405
L
N
S
S
H
P
R
S
Q
P
A
I
L
L
L
Site 76
S426
E
E
A
L
R
C
L
S
E
Q
I
A
D
A
Y
Site 77
Y433
S
E
Q
I
A
D
A
Y
S
S
F
R
S
V
R
Site 78
S434
E
Q
I
A
D
A
Y
S
S
F
R
S
V
R
A
Site 79
S435
Q
I
A
D
A
Y
S
S
F
R
S
V
R
A
I
Site 80
S438
D
A
Y
S
S
F
R
S
V
R
A
I
R
I
D
Site 81
T447
R
A
I
R
I
D
G
T
D
K
A
T
Q
D
S
Site 82
S454
T
D
K
A
T
Q
D
S
D
T
V
K
L
E
V
Site 83
T456
K
A
T
Q
D
S
D
T
V
K
L
E
V
D
Q
Site 84
Y493
A
G
S
T
L
I
F
Y
K
Y
C
D
H
E
N
Site 85
Y495
S
T
L
I
F
Y
K
Y
C
D
H
E
N
A
A
Site 86
T541
D
F
L
K
V
K
F
T
N
S
N
T
P
N
S
Site 87
S543
L
K
V
K
F
T
N
S
N
T
P
N
S
Y
N
Site 88
T545
V
K
F
T
N
S
N
T
P
N
S
Y
N
H
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation