PhosphoNET

           
Protein Info 
   
Short Name:  CRTC2
Full Name:  CREB-regulated transcription coactivator 2
Alias:  CREB-regulated transcription coactivator 2: Transducer of regulated cAMP response element-binding protein 2
Type:  Transcription protein, coactivator/corepressor
Mass (Da):  73302
Number AA:  693
UniProt ID:  Q53ET0
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0044419  GO:0045449  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T3_____MATSGANGPG
Site 2S4____MATSGANGPGS
Site 3S11SGANGPGSATASASN
Site 4T13ANGPGSATASASNPR
Site 5S15GPGSATASASNPRKF
Site 6S17GSATASASNPRKFSE
Site 7S23ASNPRKFSEKIALQK
Site 8T37KQRQAEETAAFEEVM
Site 9S49EVMMDIGSTRLQAQK
Site 10Y61AQKLRLAYTRSSHYG
Site 11T62QKLRLAYTRSSHYGG
Site 12S64LRLAYTRSSHYGGSL
Site 13S65RLAYTRSSHYGGSLP
Site 14Y67AYTRSSHYGGSLPNV
Site 15S70RSSHYGGSLPNVNQI
Site 16S79PNVNQIGSGLAEFQS
Site 17S86SGLAEFQSPLHSPLD
Site 18S90EFQSPLHSPLDSSRS
Site 19S94PLHSPLDSSRSTRHH
Site 20S95LHSPLDSSRSTRHHG
Site 21S97SPLDSSRSTRHHGLV
Site 22T98PLDSSRSTRHHGLVE
Site 23S116RDPRRMVSPLRRYTR
Site 24Y121MVSPLRRYTRHIDSS
Site 25T122VSPLRRYTRHIDSSP
Site 26S127RYTRHIDSSPYSPAY
Site 27S128YTRHIDSSPYSPAYL
Site 28Y130RHIDSSPYSPAYLSP
Site 29S131HIDSSPYSPAYLSPP
Site 30Y134SSPYSPAYLSPPPES
Site 31S136PYSPAYLSPPPESSW
Site 32S141YLSPPPESSWRRTMA
Site 33S142LSPPPESSWRRTMAW
Site 34S164GQLFRLPSALNRTSS
Site 35T169LPSALNRTSSDSALH
Site 36S170PSALNRTSSDSALHT
Site 37S171SALNRTSSDSALHTS
Site 38S173LNRTSSDSALHTSVM
Site 39T177SSDSALHTSVMNPSP
Site 40S178SDSALHTSVMNPSPQ
Site 41S183HTSVMNPSPQDTYPG
Site 42T187MNPSPQDTYPGPTPP
Site 43Y188NPSPQDTYPGPTPPS
Site 44T192QDTYPGPTPPSILPS
Site 45S195YPGPTPPSILPSRRG
Site 46S199TPPSILPSRRGGILD
Site 47S236PWDAKKLSSSSSRPR
Site 48S237WDAKKLSSSSSRPRS
Site 49S238DAKKLSSSSSRPRSC
Site 50S239AKKLSSSSSRPRSCE
Site 51S240KKLSSSSSRPRSCEV
Site 52S244SSSSRPRSCEVPGIN
Site 53S255PGINIFPSPDQPANV
Site 54S274PAMNTGGSLPDLTNL
Site 55T279GGSLPDLTNLHFPPP
Site 56T289HFPPPLPTPLDPEET
Site 57T296TPLDPEETAYPSLSG
Site 58Y298LDPEETAYPSLSGGN
Site 59S300PEETAYPSLSGGNST
Site 60S302ETAYPSLSGGNSTSN
Site 61S306PSLSGGNSTSNLTHT
Site 62S308LSGGNSTSNLTHTMT
Site 63T313STSNLTHTMTHLGIS
Site 64T315SNLTHTMTHLGISRG
Site 65Y329GMGLGPGYDAPGLHS
Site 66S336YDAPGLHSPLSHPSL
Site 67S339PGLHSPLSHPSLQSS
Site 68S342HSPLSHPSLQSSLSN
Site 69S345LSHPSLQSSLSNPNL
Site 70S346SHPSLQSSLSNPNLQ
Site 71S348PSLQSSLSNPNLQAS
Site 72S355SNPNLQASLSSPQPQ
Site 73S357PNLQASLSSPQPQLQ
Site 74S358NLQASLSSPQPQLQG
Site 75S366PQPQLQGSHSHPSLP
Site 76S368PQLQGSHSHPSLPAS
Site 77S371QGSHSHPSLPASSLA
Site 78S375SHPSLPASSLARHVL
Site 79S376HPSLPASSLARHVLP
Site 80T384LARHVLPTTSLGHPS
Site 81T385ARHVLPTTSLGHPSL
Site 82S386RHVLPTTSLGHPSLS
Site 83S391TTSLGHPSLSAPALS
Site 84S393SLGHPSLSAPALSSS
Site 85S398SLSAPALSSSSSSSS
Site 86S399LSAPALSSSSSSSST
Site 87S400SAPALSSSSSSSSTS
Site 88S401APALSSSSSSSSTSS
Site 89S402PALSSSSSSSSTSSP
Site 90S403ALSSSSSSSSTSSPV
Site 91S404LSSSSSSSSTSSPVL
Site 92S405SSSSSSSSTSSPVLG
Site 93T406SSSSSSSTSSPVLGA
Site 94S407SSSSSSTSSPVLGAP
Site 95S408SSSSSTSSPVLGAPS
Site 96S415SPVLGAPSYPASTPG
Site 97S419GAPSYPASTPGASPH
Site 98T420APSYPASTPGASPHH
Site 99S424PASTPGASPHHRRVP
Site 100S433HHRRVPLSPLSLLAG
Site 101S436RVPLSPLSLLAGPAD
Site 102S447GPADARRSQQQLPKQ
Site 103S456QQLPKQFSPTMSPTL
Site 104T458LPKQFSPTMSPTLSS
Site 105S460KQFSPTMSPTLSSIT
Site 106T462FSPTMSPTLSSITQG
Site 107S464PTMSPTLSSITQGVP
Site 108S475QGVPLDTSKLSTDQR
Site 109T479LDTSKLSTDQRLPPY
Site 110Y486TDQRLPPYPYSSPSL
Site 111Y488QRLPPYPYSSPSLVL
Site 112S489RLPPYPYSSPSLVLP
Site 113S490LPPYPYSSPSLVLPT
Site 114S492PYPYSSPSLVLPTQP
Site 115T497SPSLVLPTQPHTPKS
Site 116T501VLPTQPHTPKSLQQP
Site 117S504TQPHTPKSLQQPGLP
Site 118S512LQQPGLPSQSCSVQS
Site 119S514QPGLPSQSCSVQSSG
Site 120S516GLPSQSCSVQSSGGQ
Site 121S519SQSCSVQSSGGQPPG
Site 122S520QSCSVQSSGGQPPGR
Site 123S529GQPPGRQSHYGTPYP
Site 124Y531PPGRQSHYGTPYPPG
Site 125T533GRQSHYGTPYPPGPS
Site 126Y535QSHYGTPYPPGPSGH
Site 127S540TPYPPGPSGHGQQSY
Site 128S546PSGHGQQSYHRPMSD
Site 129Y547SGHGQQSYHRPMSDF
Site 130S552QSYHRPMSDFNLGNL
Site 131S563LGNLEQFSMESPSAS
Site 132S568QFSMESPSASLVLDP
Site 133S570SMESPSASLVLDPPG
Site 134T599GGPQDPHTFNHQNLT
Site 135S613THCSRHGSGPNIILT
Site 136T620SGPNIILTGDSSPGF
Site 137S623NIILTGDSSPGFSKE
Site 138S624IILTGDSSPGFSKEI
Site 139S628GDSSPGFSKEIAAAL
Site 140S686PDPAVEESFRSDRLQ
Site 141S689AVEESFRSDRLQ___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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