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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C20orf19
Full Name:
Centrosomal protein kizuna
Alias:
Chromosome 20 open reading frame 19; CT019; DKFZP586H021; HT013; MGC102941; MGC141930; NCRNA00153
Type:
Cell cycle regulation
Mass (Da):
75072
Number AA:
673
UniProt ID:
Q2M2Z5
International Prot ID:
IPI00335543
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
Uniprot
OncoNet
Molecular Function:
GO:0019901
PhosphoSite+
KinaseNET
Biological Process:
GO:0051300
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
A
S
A
V
P
L
S
S
P
D
Y
Y
E
R
Site 2
S13
A
S
A
V
P
L
S
S
P
D
Y
Y
E
R
L
Site 3
Y16
V
P
L
S
S
P
D
Y
Y
E
R
L
G
Q
L
Site 4
Y17
P
L
S
S
P
D
Y
Y
E
R
L
G
Q
L
Q
Site 5
S30
L
Q
H
G
L
R
D
S
E
K
K
R
L
D
L
Site 6
Y42
L
D
L
E
K
K
L
Y
E
Y
N
Q
S
D
T
Site 7
Y44
L
E
K
K
L
Y
E
Y
N
Q
S
D
T
C
R
Site 8
S47
K
L
Y
E
Y
N
Q
S
D
T
C
R
V
K
L
Site 9
T49
Y
E
Y
N
Q
S
D
T
C
R
V
K
L
K
Y
Site 10
Y56
T
C
R
V
K
L
K
Y
V
K
L
K
N
Y
L
Site 11
Y62
K
Y
V
K
L
K
N
Y
L
K
E
I
C
E
S
Site 12
S69
Y
L
K
E
I
C
E
S
E
K
K
A
H
T
R
Site 13
Y80
A
H
T
R
N
Q
E
Y
L
K
R
F
E
R
V
Site 14
S121
K
M
L
C
S
K
D
S
L
G
L
K
E
E
L
Site 15
T129
L
G
L
K
E
E
L
T
D
E
D
R
E
K
V
Site 16
S144
A
V
H
E
G
I
N
S
G
T
A
M
S
R
G
Site 17
S169
R
Q
M
S
A
I
L
S
M
R
D
F
S
T
E
Site 18
S174
I
L
S
M
R
D
F
S
T
E
H
K
S
P
Q
Site 19
T175
L
S
M
R
D
F
S
T
E
H
K
S
P
Q
P
Site 20
S179
D
F
S
T
E
H
K
S
P
Q
P
T
K
N
F
Site 21
T183
E
H
K
S
P
Q
P
T
K
N
F
S
I
P
D
Site 22
S187
P
Q
P
T
K
N
F
S
I
P
D
P
H
S
H
Site 23
S193
F
S
I
P
D
P
H
S
H
R
Q
T
A
Q
S
Site 24
T197
D
P
H
S
H
R
Q
T
A
Q
S
S
N
V
T
Site 25
S200
S
H
R
Q
T
A
Q
S
S
N
V
T
D
S
C
Site 26
T204
T
A
Q
S
S
N
V
T
D
S
C
V
V
Q
T
Site 27
S206
Q
S
S
N
V
T
D
S
C
V
V
Q
T
S
N
Site 28
S221
D
T
Q
C
L
N
K
S
D
N
I
D
G
K
A
Site 29
T239
I
G
E
K
M
P
V
T
A
S
V
L
S
E
E
Site 30
S241
E
K
M
P
V
T
A
S
V
L
S
E
E
E
Q
Site 31
S244
P
V
T
A
S
V
L
S
E
E
E
Q
T
H
C
Site 32
T249
V
L
S
E
E
E
Q
T
H
C
L
E
I
G
S
Site 33
S256
T
H
C
L
E
I
G
S
N
T
R
H
G
K
S
Site 34
S263
S
N
T
R
H
G
K
S
N
L
S
E
G
K
K
Site 35
S266
R
H
G
K
S
N
L
S
E
G
K
K
S
A
E
Site 36
S271
N
L
S
E
G
K
K
S
A
E
L
N
S
P
L
Site 37
S276
K
K
S
A
E
L
N
S
P
L
R
E
R
L
S
Site 38
S283
S
P
L
R
E
R
L
S
P
E
N
R
T
T
D
Site 39
T289
L
S
P
E
N
R
T
T
D
L
K
C
D
S
S
Site 40
S295
T
T
D
L
K
C
D
S
S
S
G
S
E
G
E
Site 41
S296
T
D
L
K
C
D
S
S
S
G
S
E
G
E
I
Site 42
S297
D
L
K
C
D
S
S
S
G
S
E
G
E
I
L
Site 43
S299
K
C
D
S
S
S
G
S
E
G
E
I
L
T
R
Site 44
S317
E
V
E
E
K
R
A
S
P
P
V
S
P
I
P
Site 45
S321
K
R
A
S
P
P
V
S
P
I
P
V
S
E
Y
Site 46
S326
P
V
S
P
I
P
V
S
E
Y
C
E
S
E
N
Site 47
Y328
S
P
I
P
V
S
E
Y
C
E
S
E
N
K
W
Site 48
S331
P
V
S
E
Y
C
E
S
E
N
K
W
S
Q
E
Site 49
S341
K
W
S
Q
E
K
H
S
P
W
E
G
V
S
D
Site 50
S357
L
A
H
R
E
P
K
S
Q
K
P
F
R
K
M
Site 51
S371
M
Q
E
E
E
E
E
S
W
S
T
S
S
D
L
Site 52
S373
E
E
E
E
E
S
W
S
T
S
S
D
L
T
I
Site 53
T374
E
E
E
E
S
W
S
T
S
S
D
L
T
I
S
Site 54
S375
E
E
E
S
W
S
T
S
S
D
L
T
I
S
I
Site 55
S376
E
E
S
W
S
T
S
S
D
L
T
I
S
I
S
Site 56
T379
W
S
T
S
S
D
L
T
I
S
I
S
E
D
D
Site 57
S381
T
S
S
D
L
T
I
S
I
S
E
D
D
L
I
Site 58
S391
E
D
D
L
I
L
E
S
P
E
P
Q
P
N
P
Site 59
S424
E
Q
E
R
V
A
L
S
T
E
K
N
C
I
L
Site 60
T425
Q
E
R
V
A
L
S
T
E
K
N
C
I
L
Q
Site 61
T433
E
K
N
C
I
L
Q
T
L
S
S
P
D
S
E
Site 62
S435
N
C
I
L
Q
T
L
S
S
P
D
S
E
K
E
Site 63
S436
C
I
L
Q
T
L
S
S
P
D
S
E
K
E
S
Site 64
S439
Q
T
L
S
S
P
D
S
E
K
E
S
S
T
N
Site 65
S443
S
P
D
S
E
K
E
S
S
T
N
A
P
T
R
Site 66
S444
P
D
S
E
K
E
S
S
T
N
A
P
T
R
E
Site 67
T449
E
S
S
T
N
A
P
T
R
E
P
G
Q
T
P
Site 68
T455
P
T
R
E
P
G
Q
T
P
D
S
D
V
P
R
Site 69
S458
E
P
G
Q
T
P
D
S
D
V
P
R
A
Q
V
Site 70
S478
T
L
K
E
H
D
N
S
V
K
E
E
A
T
A
Site 71
T492
A
L
L
R
K
A
L
T
E
E
C
G
R
R
S
Site 72
S499
T
E
E
C
G
R
R
S
A
I
H
S
S
E
S
Site 73
S503
G
R
R
S
A
I
H
S
S
E
S
S
C
S
L
Site 74
S504
R
R
S
A
I
H
S
S
E
S
S
C
S
L
P
Site 75
S506
S
A
I
H
S
S
E
S
S
C
S
L
P
S
I
Site 76
S509
H
S
S
E
S
S
C
S
L
P
S
I
L
N
D
Site 77
S512
E
S
S
C
S
L
P
S
I
L
N
D
N
S
G
Site 78
S518
P
S
I
L
N
D
N
S
G
I
K
E
A
K
P
Site 79
S531
K
P
A
V
W
L
N
S
V
P
T
R
E
Q
E
Site 80
S540
P
T
R
E
Q
E
V
S
S
G
C
G
D
K
S
Site 81
S541
T
R
E
Q
E
V
S
S
G
C
G
D
K
S
K
Site 82
S547
S
S
G
C
G
D
K
S
K
K
E
N
V
A
A
Site 83
Y564
P
I
T
E
T
E
A
Y
Q
L
L
K
K
A
T
Site 84
T586
T
E
N
R
F
Q
K
T
D
A
S
V
S
H
L
Site 85
S589
R
F
Q
K
T
D
A
S
V
S
H
L
S
G
L
Site 86
S591
Q
K
T
D
A
S
V
S
H
L
S
G
L
N
I
Site 87
S594
D
A
S
V
S
H
L
S
G
L
N
I
G
S
G
Site 88
S600
L
S
G
L
N
I
G
S
G
A
F
E
T
K
T
Site 89
T605
I
G
S
G
A
F
E
T
K
T
A
N
K
I
A
Site 90
T607
S
G
A
F
E
T
K
T
A
N
K
I
A
S
E
Site 91
S613
K
T
A
N
K
I
A
S
E
A
S
F
S
S
S
Site 92
S616
N
K
I
A
S
E
A
S
F
S
S
S
E
G
S
Site 93
S618
I
A
S
E
A
S
F
S
S
S
E
G
S
P
L
Site 94
S619
A
S
E
A
S
F
S
S
S
E
G
S
P
L
S
Site 95
S620
S
E
A
S
F
S
S
S
E
G
S
P
L
S
R
Site 96
S623
S
F
S
S
S
E
G
S
P
L
S
R
H
E
N
Site 97
S626
S
S
E
G
S
P
L
S
R
H
E
N
K
K
K
Site 98
S640
K
P
V
I
N
L
K
S
N
A
L
W
D
E
S
Site 99
S647
S
N
A
L
W
D
E
S
D
D
S
N
S
E
I
Site 100
S650
L
W
D
E
S
D
D
S
N
S
E
I
E
A
A
Site 101
S652
D
E
S
D
D
S
N
S
E
I
E
A
A
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation