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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DBN1
Full Name:
Drebrin
Alias:
D0S117E; Developmentally regulated brain protein; Developmentally-regulated brain protein; DRBA; DREB; Drebrin 1
Type:
Actin binding protein; Cytoskeletal protein
Mass (Da):
71429
Number AA:
649
UniProt ID:
Q16643
International Prot ID:
IPI00003406
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042641
GO:0005737
GO:0030425
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005522
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007015
GO:0050773
GO:0048168
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
G
V
S
F
S
G
H
R
L
E
L
L
Site 2
Y17
R
L
E
L
L
A
A
Y
E
E
V
I
R
E
E
Site 3
S25
E
E
V
I
R
E
E
S
A
A
D
W
A
L
Y
Site 4
Y32
S
A
A
D
W
A
L
Y
T
Y
E
D
G
S
D
Site 5
T33
A
A
D
W
A
L
Y
T
Y
E
D
G
S
D
D
Site 6
Y34
A
D
W
A
L
Y
T
Y
E
D
G
S
D
D
L
Site 7
S38
L
Y
T
Y
E
D
G
S
D
D
L
K
L
A
A
Site 8
S46
D
D
L
K
L
A
A
S
G
E
G
G
L
Q
E
Site 9
S55
E
G
G
L
Q
E
L
S
G
H
F
E
N
Q
K
Site 10
Y65
F
E
N
Q
K
V
M
Y
G
F
C
S
V
K
D
Site 11
S69
K
V
M
Y
G
F
C
S
V
K
D
S
Q
A
A
Site 12
S73
G
F
C
S
V
K
D
S
Q
A
A
L
P
K
Y
Site 13
S134
G
A
I
G
Q
R
L
S
N
G
L
A
R
L
S
Site 14
S141
S
N
G
L
A
R
L
S
S
P
V
L
H
R
L
Site 15
S142
N
G
L
A
R
L
S
S
P
V
L
H
R
L
R
Site 16
Y163
A
E
P
V
G
T
T
Y
Q
K
T
D
A
A
V
Site 17
T166
V
G
T
T
Y
Q
K
T
D
A
A
V
E
M
K
Site 18
Y225
Q
E
E
R
E
R
R
Y
R
E
R
E
Q
Q
I
Site 19
T241
E
H
R
R
K
Q
Q
T
L
E
A
E
E
A
K
Site 20
S255
K
R
R
L
K
E
Q
S
I
F
G
D
H
R
D
Site 21
T267
H
R
D
E
E
E
E
T
H
M
K
K
S
E
S
Site 22
S272
E
E
T
H
M
K
K
S
E
S
E
V
E
E
A
Site 23
S274
T
H
M
K
K
S
E
S
E
V
E
E
A
A
A
Site 24
S302
K
Q
Q
E
R
V
A
S
A
S
A
G
S
C
D
Site 25
S304
Q
E
R
V
A
S
A
S
A
G
S
C
D
V
P
Site 26
S307
V
A
S
A
S
A
G
S
C
D
V
P
S
P
F
Site 27
S312
A
G
S
C
D
V
P
S
P
F
N
H
R
P
G
Site 28
S320
P
F
N
H
R
P
G
S
H
L
D
S
H
R
R
Site 29
S324
R
P
G
S
H
L
D
S
H
R
R
M
A
P
T
Site 30
T331
S
H
R
R
M
A
P
T
P
I
P
T
R
S
P
Site 31
T335
M
A
P
T
P
I
P
T
R
S
P
S
D
S
S
Site 32
S337
P
I
P
T
R
S
P
S
D
S
S
T
A
S
T
Site 33
S339
P
I
P
T
R
S
P
S
D
S
S
T
A
S
T
Site 34
S341
T
R
S
P
S
D
S
S
T
A
S
T
P
V
A
Site 35
S342
T
R
S
P
S
D
S
S
T
A
S
T
P
V
A
Site 36
T343
R
S
P
S
D
S
S
T
A
S
T
P
V
A
E
Site 37
S345
P
S
D
S
S
T
A
S
T
P
V
A
E
Q
I
Site 38
T346
S
D
S
S
T
A
S
T
P
V
A
E
Q
I
E
Site 39
T360
E
R
A
L
D
E
V
T
S
S
Q
P
P
P
L
Site 40
S361
R
A
L
D
E
V
T
S
S
Q
P
P
P
L
P
Site 41
S362
A
L
D
E
V
T
S
S
Q
P
P
P
L
P
P
Site 42
T377
P
P
P
P
A
Q
E
T
Q
E
P
S
P
I
L
Site 43
S381
A
Q
E
T
Q
E
P
S
P
I
L
D
S
E
E
Site 44
S386
E
P
S
P
I
L
D
S
E
E
T
R
A
A
A
Site 45
S416
A
P
P
R
G
P
G
S
P
A
E
D
L
M
F
Site 46
T463
D
T
A
T
A
D
T
T
V
A
N
N
V
P
P
Site 47
S487
P
G
N
G
E
G
A
S
T
L
Q
G
E
P
R
Site 48
T488
G
N
G
E
G
A
S
T
L
Q
G
E
P
R
A
Site 49
T497
Q
G
E
P
R
A
P
T
P
P
S
G
T
E
V
Site 50
S500
P
R
A
P
T
P
P
S
G
T
E
V
T
L
A
Site 51
T542
E
L
P
E
P
P
A
T
F
C
D
P
E
E
V
Site 52
T559
E
S
L
A
A
P
Q
T
P
T
L
P
S
A
L
Site 53
S564
P
Q
T
P
T
L
P
S
A
L
E
E
L
E
Q
Site 54
S594
Q
K
E
G
T
Q
A
S
E
G
Y
F
S
Q
S
Site 55
Y597
G
T
Q
A
S
E
G
Y
F
S
Q
S
Q
E
E
Site 56
S599
Q
A
S
E
G
Y
F
S
Q
S
Q
E
E
E
F
Site 57
S601
S
E
G
Y
F
S
Q
S
Q
E
E
E
F
A
Q
Site 58
S609
Q
E
E
E
F
A
Q
S
E
E
L
C
A
K
A
Site 59
Y622
K
A
P
P
P
V
F
Y
N
K
P
P
E
I
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation