KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
STX1A
Full Name:
Syntaxin-1A
Alias:
HPC-1; Neuron-specific antigen HPC-1; P35-1; P35A; SAP; STX1; Synaptotagmin associated 35 kDa protein; Syntaxin 1A (brain)
Type:
Vesicle protein
Mass (Da):
33023
Number AA:
288
UniProt ID:
Q16623
International Prot ID:
IPI00003370
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005484
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0050796
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
D
R
T
Q
E
L
R
T
A
K
D
S
D
D
D
Site 2
S14
E
L
R
T
A
K
D
S
D
D
D
D
D
V
A
Site 3
S59
E
E
V
K
R
K
H
S
A
I
L
A
S
P
N
Site 4
S64
K
H
S
A
I
L
A
S
P
N
P
D
E
K
T
Site 5
T71
S
P
N
P
D
E
K
T
K
E
E
L
E
E
L
Site 6
S80
E
E
L
E
E
L
M
S
D
I
K
K
T
A
N
Site 7
S91
K
T
A
N
K
V
R
S
K
L
K
S
I
E
Q
Site 8
S95
K
V
R
S
K
L
K
S
I
E
Q
S
I
E
Q
Site 9
S99
K
L
K
S
I
E
Q
S
I
E
Q
E
E
G
L
Site 10
S110
E
E
G
L
N
R
S
S
A
D
L
R
I
R
K
Site 11
T118
A
D
L
R
I
R
K
T
Q
H
S
T
L
S
R
Site 12
S121
R
I
R
K
T
Q
H
S
T
L
S
R
K
F
V
Site 13
T122
I
R
K
T
Q
H
S
T
L
S
R
K
F
V
E
Site 14
S132
R
K
F
V
E
V
M
S
E
Y
N
A
T
Q
S
Site 15
Y134
F
V
E
V
M
S
E
Y
N
A
T
Q
S
D
Y
Site 16
T137
V
M
S
E
Y
N
A
T
Q
S
D
Y
R
E
R
Site 17
S139
S
E
Y
N
A
T
Q
S
D
Y
R
E
R
C
K
Site 18
Y141
Y
N
A
T
Q
S
D
Y
R
E
R
C
K
G
R
Site 19
T156
I
Q
R
Q
L
E
I
T
G
R
T
T
T
S
E
Site 20
T160
L
E
I
T
G
R
T
T
T
S
E
E
L
E
D
Site 21
T161
E
I
T
G
R
T
T
T
S
E
E
L
E
D
M
Site 22
S162
I
T
G
R
T
T
T
S
E
E
L
E
D
M
L
Site 23
S188
I
I
M
D
S
S
I
S
K
Q
A
L
S
E
I
Site 24
S193
S
I
S
K
Q
A
L
S
E
I
E
T
R
H
S
Site 25
T197
Q
A
L
S
E
I
E
T
R
H
S
E
I
I
K
Site 26
S200
S
E
I
E
T
R
H
S
E
I
I
K
L
E
N
Site 27
S208
E
I
I
K
L
E
N
S
I
R
E
L
H
D
M
Site 28
Y235
E
M
I
D
R
I
E
Y
N
V
E
H
A
V
D
Site 29
Y243
N
V
E
H
A
V
D
Y
V
E
R
A
V
S
D
Site 30
S249
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Site 31
T251
V
E
R
A
V
S
D
T
K
K
A
V
K
Y
Q
Site 32
Y257
D
T
K
K
A
V
K
Y
Q
S
K
A
R
R
K
Site 33
S259
K
K
A
V
K
Y
Q
S
K
A
R
R
K
K
I
Site 34
S281
I
L
G
I
V
I
A
S
T
V
G
G
I
F
A
Site 35
T282
L
G
I
V
I
A
S
T
V
G
G
I
F
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation