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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cdc37
Full Name:
Hsp90 co-chaperone Cdc37
Alias:
CC37; CDC37 (cell division cycle 37,); CDC37 cell division cycle 37; Cell division cycle 37; Hsp90 co-chaperone Cdc37; P50Cdc37
Type:
Chaperone protein
Mass (Da):
44468
Number AA:
378
UniProt ID:
Q16543
International Prot ID:
IPI00013122
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0031072
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006605
GO:0000079
GO:0060334
Phosida
TranscriptoNet
STRING
Kinexus Products
Hsp90 co-chaperone Cdc37 pan-specific antibody AB-NN230-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN230-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
V
D
Y
S
V
W
D
H
I
E
V
Site 2
S13
V
W
D
H
I
E
V
S
D
D
E
D
E
T
H
Site 3
T19
V
S
D
D
E
D
E
T
H
P
N
I
D
T
A
Site 4
T25
E
T
H
P
N
I
D
T
A
S
L
F
R
W
R
Site 5
S97
Q
L
R
K
E
E
R
S
W
E
Q
K
L
E
E
Site 6
S111
E
M
R
K
K
E
K
S
M
P
W
N
V
D
T
Site 7
T118
S
M
P
W
N
V
D
T
L
S
K
D
G
F
S
Site 8
S120
P
W
N
V
D
T
L
S
K
D
G
F
S
K
S
Site 9
S127
S
K
D
G
F
S
K
S
M
V
N
T
K
P
E
Site 10
T131
F
S
K
S
M
V
N
T
K
P
E
K
T
E
E
Site 11
T136
V
N
T
K
P
E
K
T
E
E
D
S
E
E
V
Site 12
S140
P
E
K
T
E
E
D
S
E
E
V
R
E
Q
K
Site 13
T150
V
R
E
Q
K
H
K
T
F
V
E
K
Y
E
K
Site 14
Y155
H
K
T
F
V
E
K
Y
E
K
Q
I
K
H
F
Site 15
S171
M
L
R
R
W
D
D
S
Q
K
Y
L
S
D
N
Site 16
Y174
R
W
D
D
S
Q
K
Y
L
S
D
N
V
H
L
Site 17
S176
D
D
S
Q
K
Y
L
S
D
N
V
H
L
V
C
Site 18
T243
Q
F
F
T
K
I
K
T
A
D
R
Q
Y
M
E
Site 19
Y248
I
K
T
A
D
R
Q
Y
M
E
G
F
N
D
E
Site 20
Y278
I
E
K
A
M
K
E
Y
E
E
E
E
R
K
K
Site 21
Y298
G
L
D
P
V
E
V
Y
E
S
L
P
E
E
L
Site 22
S300
D
P
V
E
V
Y
E
S
L
P
E
E
L
Q
K
Site 23
S322
Q
M
L
Q
D
A
I
S
K
M
D
P
T
D
A
Site 24
T327
A
I
S
K
M
D
P
T
D
A
K
Y
H
M
Q
Site 25
Y331
M
D
P
T
D
A
K
Y
H
M
Q
R
C
I
D
Site 26
S346
S
G
L
W
V
P
N
S
K
A
S
E
A
K
E
Site 27
T370
L
L
E
A
V
P
K
T
G
D
E
K
D
V
S
Site 28
S377
T
G
D
E
K
D
V
S
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation