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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIP6
Full Name:
Thyroid receptor-interacting protein 6
Alias:
MGC10556; MGC10558; MGC29959; MGC3837; MGC4423; OIP1; OPA-interacting protein 1; Thyroid hormone receptor interactor 6; Thyroid receptor interacting protein 6; TRI6; ZRP-1; Zyxin related protein 1
Type:
Adaptor/scaffold; Nuclear receptor co-regulator
Mass (Da):
50288
Number AA:
476
UniProt ID:
Q15654
International Prot ID:
IPI00301561
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005925
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0005149
GO:0019900
PhosphoSite+
KinaseNET
Biological Process:
GO:0048041
GO:0030335
GO:0008588
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
G
R
A
I
P
R
G
T
P
G
P
P
P
A
H
Site 2
S51
V
N
F
C
P
L
P
S
E
Q
C
Y
Q
A
P
Site 3
Y55
P
L
P
S
E
Q
C
Y
Q
A
P
G
G
P
E
Site 4
S71
R
G
P
A
W
V
G
S
H
G
V
L
Q
H
T
Site 5
S92
R
G
G
L
R
P
G
S
L
D
A
E
I
D
L
Site 6
S115
N
G
G
R
G
H
A
S
R
R
P
D
R
Q
A
Site 7
Y123
R
R
P
D
R
Q
A
Y
E
P
P
P
P
P
A
Site 8
Y131
E
P
P
P
P
P
A
Y
R
T
G
S
L
K
P
Site 9
T133
P
P
P
P
A
Y
R
T
G
S
L
K
P
N
P
Site 10
S135
P
P
A
Y
R
T
G
S
L
K
P
N
P
A
S
Site 11
S142
S
L
K
P
N
P
A
S
P
L
P
A
S
P
Y
Site 12
S147
P
A
S
P
L
P
A
S
P
Y
G
G
P
T
P
Site 13
Y149
S
P
L
P
A
S
P
Y
G
G
P
T
P
A
S
Site 14
T153
A
S
P
Y
G
G
P
T
P
A
S
Y
T
T
A
Site 15
S156
Y
G
G
P
T
P
A
S
Y
T
T
A
S
T
P
Site 16
Y157
G
G
P
T
P
A
S
Y
T
T
A
S
T
P
A
Site 17
T159
P
T
P
A
S
Y
T
T
A
S
T
P
A
G
P
Site 18
S161
P
A
S
Y
T
T
A
S
T
P
A
G
P
A
F
Site 19
T162
A
S
Y
T
T
A
S
T
P
A
G
P
A
F
P
Site 20
S189
G
P
P
R
R
G
A
S
Q
A
S
G
P
L
P
Site 21
Y213
G
E
V
W
G
P
G
Y
R
S
Q
R
E
P
G
Site 22
S215
V
W
G
P
G
Y
R
S
Q
R
E
P
G
P
G
Site 23
S249
H
G
P
Q
V
P
L
S
Q
P
P
E
D
E
L
Site 24
T260
E
D
E
L
D
R
L
T
K
K
L
V
H
D
M
Site 25
Y275
N
H
P
P
S
G
E
Y
F
G
Q
C
G
G
C
Site 26
Y320
Q
L
R
G
Q
H
F
Y
A
V
E
R
R
A
Y
Site 27
Y327
Y
A
V
E
R
R
A
Y
C
E
G
C
Y
V
A
Site 28
Y332
R
A
Y
C
E
G
C
Y
V
A
T
L
E
K
C
Site 29
T415
P
E
P
G
Q
E
E
T
V
R
I
V
A
L
D
Site 30
Y430
R
S
F
H
I
G
C
Y
K
C
E
E
C
G
L
Site 31
S440
E
E
C
G
L
L
L
S
S
E
G
E
C
Q
G
Site 32
Y449
E
G
E
C
Q
G
C
Y
P
L
D
G
H
I
L
Site 33
S469
A
W
R
I
Q
E
L
S
A
T
V
T
T
D
C
Site 34
T471
R
I
Q
E
L
S
A
T
V
T
T
D
C
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation