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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SF3A1
Full Name:
Splicing factor 3A subunit 1
Alias:
SAP 114; SF3a120; Spliceosome associated protein 114; Spliceosome-associated protein 114
Type:
RNA binding protein
Mass (Da):
88886
Number AA:
793
UniProt ID:
Q15459
International Prot ID:
IPI00017451
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005684
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000389
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
P
P
P
P
P
V
P
T
E
P
K
Q
P
T
E
Site 2
S28
Q
P
T
E
E
E
A
S
S
K
E
D
S
A
P
Site 3
S29
P
T
E
E
E
A
S
S
K
E
D
S
A
P
S
Site 4
S33
E
A
S
S
K
E
D
S
A
P
S
K
P
V
V
Site 5
Y44
K
P
V
V
G
I
I
Y
P
P
P
E
V
R
N
Site 6
T56
V
R
N
I
V
D
K
T
A
S
F
V
A
R
N
Site 7
S58
N
I
V
D
K
T
A
S
F
V
A
R
N
G
P
Site 8
Y90
F
L
N
P
N
D
P
Y
H
A
Y
Y
R
H
K
Site 9
Y93
P
N
D
P
Y
H
A
Y
Y
R
H
K
V
S
E
Site 10
Y94
N
D
P
Y
H
A
Y
Y
R
H
K
V
S
E
F
Site 11
S110
E
G
K
A
Q
E
P
S
A
A
I
P
K
V
M
Site 12
T124
M
Q
Q
Q
Q
Q
T
T
Q
Q
Q
L
P
Q
K
Site 13
T140
Q
A
Q
V
I
Q
E
T
I
V
P
K
E
P
P
Site 14
Y193
M
Q
K
E
Q
R
N
Y
Q
F
D
F
L
R
P
Site 15
S203
D
F
L
R
P
Q
H
S
L
F
N
Y
F
T
K
Site 16
Y207
P
Q
H
S
L
F
N
Y
F
T
K
L
V
E
Q
Site 17
Y245
E
V
L
D
Q
V
C
Y
R
V
E
W
A
K
F
Site 18
Y271
K
E
K
E
R
V
A
Y
A
Q
I
D
W
H
D
Site 19
T284
H
D
F
V
V
V
E
T
V
D
F
Q
P
N
E
Site 20
T299
Q
G
N
F
P
P
P
T
T
P
E
E
L
G
A
Site 21
T300
G
N
F
P
P
P
T
T
P
E
E
L
G
A
R
Site 22
Y314
R
I
L
I
Q
E
R
Y
E
K
F
G
E
S
E
Site 23
S320
R
Y
E
K
F
G
E
S
E
E
V
E
M
E
V
Site 24
S329
E
V
E
M
E
V
E
S
D
E
E
D
D
K
Q
Site 25
S344
E
K
A
E
E
P
P
S
Q
L
D
Q
D
T
Q
Site 26
T350
P
S
Q
L
D
Q
D
T
Q
V
Q
D
M
D
E
Site 27
S359
V
Q
D
M
D
E
G
S
D
D
E
E
E
G
Q
Site 28
T374
K
V
P
P
P
P
E
T
P
M
P
P
P
L
P
Site 29
T383
M
P
P
P
L
P
P
T
P
D
Q
V
I
V
R
Site 30
Y393
Q
V
I
V
R
K
D
Y
D
P
K
A
S
K
P
Site 31
S398
K
D
Y
D
P
K
A
S
K
P
L
P
P
A
P
Site 32
Y410
P
A
P
A
P
D
E
Y
L
V
S
P
I
T
G
Site 33
S413
A
P
D
E
Y
L
V
S
P
I
T
G
E
K
I
Site 34
T416
E
Y
L
V
S
P
I
T
G
E
K
I
P
A
S
Site 35
S423
T
G
E
K
I
P
A
S
K
M
Q
E
H
M
R
Site 36
S445
W
L
E
Q
R
D
R
S
I
R
E
K
Q
S
D
Site 37
S451
R
S
I
R
E
K
Q
S
D
D
E
V
Y
A
P
Site 38
Y456
K
Q
S
D
D
E
V
Y
A
P
G
L
D
I
E
Site 39
S464
A
P
G
L
D
I
E
S
S
L
K
Q
L
A
E
Site 40
S465
P
G
L
D
I
E
S
S
L
K
Q
L
A
E
R
Site 41
T474
K
Q
L
A
E
R
R
T
D
I
F
G
V
E
E
Site 42
T501
Q
K
P
E
E
K
V
T
W
D
G
H
S
G
S
Site 43
S508
T
W
D
G
H
S
G
S
M
A
R
T
Q
Q
A
Site 44
T512
H
S
G
S
M
A
R
T
Q
Q
A
A
Q
A
N
Site 45
T541
G
L
V
P
E
D
D
T
K
E
K
I
G
P
S
Site 46
S561
P
Q
Q
P
P
P
P
S
S
A
T
N
I
P
S
Site 47
S562
Q
Q
P
P
P
P
S
S
A
T
N
I
P
S
S
Site 48
T564
P
P
P
P
S
S
A
T
N
I
P
S
S
A
P
Site 49
S568
S
S
A
T
N
I
P
S
S
A
P
P
I
T
S
Site 50
T574
P
S
S
A
P
P
I
T
S
V
P
R
P
P
T
Site 51
S575
S
S
A
P
P
I
T
S
V
P
R
P
P
T
M
Site 52
T581
T
S
V
P
R
P
P
T
M
P
P
P
V
R
T
Site 53
S604
M
P
R
P
P
M
A
S
V
V
R
L
P
P
G
Site 54
T681
P
P
M
E
D
E
P
T
S
K
K
L
K
T
E
Site 55
S682
P
M
E
D
E
P
T
S
K
K
L
K
T
E
D
Site 56
T687
P
T
S
K
K
L
K
T
E
D
S
L
M
P
E
Site 57
S690
K
K
L
K
T
E
D
S
L
M
P
E
E
E
F
Site 58
S706
R
R
N
K
G
P
V
S
I
K
V
Q
V
P
N
Site 59
Y759
A
G
K
Q
K
L
Q
Y
E
G
I
F
I
K
D
Site 60
S767
E
G
I
F
I
K
D
S
N
S
L
A
Y
Y
N
Site 61
Y773
D
S
N
S
L
A
Y
Y
N
M
A
N
G
A
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation