PhosphoNET

           
Protein Info 
   
Short Name:  PCM1
Full Name:  Pericentriolar material 1 protein
Alias:  HPCM-1; PCM-1; Pericentriol material 1; Pericentriolar material 1; Pericentriolar material 1 (PTC4); Pericentriolar material-1; PTC4
Type:  Cell cycle regulation
Mass (Da):  228485
Number AA:  2024
UniProt ID:  Q15154
International Prot ID:  IPI00006213
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0034451  GO:0005829  GO:0000242 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0005515  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0051297  GO:0042384  GO:0009653 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S45QKKANRSSEKNKKKF
Site 2S56KKKFGVESDKRVTND
Site 3T61VESDKRVTNDISPES
Site 4S65KRVTNDISPESSPGV
Site 5S68TNDISPESSPGVGRR
Site 6S69NDISPESSPGVGRRR
Site 7T77PGVGRRRTKTPHTFP
Site 8T79VGRRRTKTPHTFPHS
Site 9T82RRTKTPHTFPHSRYM
Site 10Y88HTFPHSRYMSQMSVP
Site 11S90FPHSRYMSQMSVPEQ
Site 12S93SRYMSQMSVPEQAEL
Site 13S110LKQRINFSDLDQRSI
Site 14S116FSDLDQRSIGSDSQG
Site 15S119LDQRSIGSDSQGRAT
Site 16S121QRSIGSDSQGRATAA
Site 17T126SDSQGRATAANNKRQ
Site 18S135ANNKRQLSENRKPFN
Site 19S153MQINTNKSKDASTSP
Site 20S157TNKSKDASTSPPNRE
Site 21T158NKSKDASTSPPNRET
Site 22S159KSKDASTSPPNRETI
Site 23T165TSPPNRETIGSAQCK
Site 24S168PNRETIGSAQCKELF
Site 25S190LLQNCQVSEEDGRGE
Site 26S202RGEPAMESSQIVSRL
Site 27S203GEPAMESSQIVSRLV
Site 28S207MESSQIVSRLVQIRD
Site 29Y215RLVQIRDYITKASSM
Site 30T217VQIRDYITKASSMRE
Site 31S220RDYITKASSMREDLV
Site 32S221DYITKASSMREDLVE
Site 33T240SANVERLTHLIDHLK
Site 34S252HLKEQEKSYMKFLKK
Site 35S330AETAGSLSGVSITSE
Site 36S333AGSLSGVSITSELNE
Site 37S356FHNQLRDSQPPAVPD
Site 38S370DNRRQAESLSLTREV
Site 39S372RRQAESLSLTREVSQ
Site 40S378LSLTREVSQSRKPSA
Site 41S380LTREVSQSRKPSASE
Site 42S384VSQSRKPSASERLPD
Site 43S386QSRKPSASERLPDEK
Site 44T419KLLGELHTLRDQHLN
Site 45S428RDQHLNNSSASPQRS
Site 46S429DQHLNNSSASPQRSV
Site 47S431HLNNSSASPQRSVDQ
Site 48S435SSASPQRSVDQRSTS
Site 49S440QRSVDQRSTSAPSAS
Site 50T441RSVDQRSTSAPSASV
Site 51S442SVDQRSTSAPSASVG
Site 52S445QRSTSAPSASVGLAP
Site 53S458APVVNGESNSLTSSV
Site 54S460VVNGESNSLTSSVPY
Site 55T462NGESNSLTSSVPYPT
Site 56S464ESNSLTSSVPYPTAS
Site 57S471SVPYPTASLVSQNES
Site 58S474YPTASLVSQNESENE
Site 59S478SLVSQNESENEGHLN
Site 60Y509ELRELVHYYEQTSDM
Site 61Y510LRELVHYYEQTSDMM
Site 62T518EQTSDMMTDAVNENR
Site 63T530ENRKDEETEESEYDS
Site 64S533KDEETEESEYDSEHE
Site 65Y535EETEESEYDSEHENS
Site 66S537TEESEYDSEHENSEP
Site 67S542YDSEHENSEPVTNIR
Site 68T546HENSEPVTNIRNPQV
Site 69S570HSNAQCVSNNRDGRT
Site 70T577SNNRDGRTVNSNCEI
Site 71S580RDGRTVNSNCEINNR
Site 72S600RALNVPPSLDCRYNR
Site 73Y605PPSLDCRYNREGEQE
Site 74S634EAEEEGVSGASLSSH
Site 75S637EEGVSGASLSSHRSS
Site 76S639GVSGASLSSHRSSLV
Site 77S640VSGASLSSHRSSLVD
Site 78S643ASLSSHRSSLVDEHP
Site 79S644SLSSHRSSLVDEHPE
Site 80S690DAAQGVISASASNLD
Site 81S694GVISASASNLDDFYP
Site 82Y700ASNLDDFYPAEEDTK
Site 83T720TRGNANKTQKDTGVN
Site 84T724ANKTQKDTGVNEKAR
Site 85T768EKIQALQTACPDLQL
Site 86T785ASVGNCPTKKYMPAV
Site 87Y788GNCPTKKYMPAVTST
Site 88T795YMPAVTSTPTVNQHE
Site 89T797PAVTSTPTVNQHETS
Site 90S804TVNQHETSTSKSVFE
Site 91T805VNQHETSTSKSVFEP
Site 92S806NQHETSTSKSVFEPE
Site 93S808HETSTSKSVFEPEDS
Site 94S815SVFEPEDSSIVDNEL
Site 95S816VFEPEDSSIVDNELW
Site 96T859RRQGLAETASPVAVS
Site 97S861QGLAETASPVAVSLR
Site 98S866TASPVAVSLRSDGSE
Site 99S869PVAVSLRSDGSENLC
Site 100S872VSLRSDGSENLCTPQ
Site 101T877DGSENLCTPQQSRTE
Site 102T889RTEKTMATWGGSTQC
Site 103Y907EEGDEDGYLSEGIVR
Site 104S909GDEDGYLSEGIVRTD
Site 105S926EEEEQDASSNDNFSV
Site 106S927EEEQDASSNDNFSVC
Site 107S932ASSNDNFSVCPSNSV
Site 108S936DNFSVCPSNSVNHNS
Site 109S960WKNNCPFSADENYRP
Site 110Y965PFSADENYRPLAKTR
Site 111T971NYRPLAKTRQQNISM
Site 112S977KTRQQNISMQRQENL
Site 113S988QENLRWVSELSYVEE
Site 114S991LRWVSELSYVEEKEQ
Site 115Y992RWVSELSYVEEKEQW
Site 116T1019FSVSICQTLMQDQQT
Site 117T1026TLMQDQQTLSCLLQT
Site 118S1044GPYSVMPSNVASPQV
Site 119S1100PGGKERGSSASHPPS
Site 120S1101GGKERGSSASHPPSP
Site 121S1103KERGSSASHPPSPSL
Site 122S1107SSASHPPSPSLFCPF
Site 123S1109ASHPPSPSLFCPFSF
Site 124S1134PGFTNFSSFAPGMNF
Site 125S1147NFSPLFPSNFGDFSQ
Site 126S1153PSNFGDFSQNISTPS
Site 127S1157GDFSQNISTPSEQQQ
Site 128T1158DFSQNISTPSEQQQP
Site 129S1171QPLAQNSSGKTEYMA
Site 130T1174AQNSSGKTEYMAFPK
Site 131Y1176NSSGKTEYMAFPKPF
Site 132S1185AFPKPFESSSSIGAE
Site 133S1186FPKPFESSSSIGAEK
Site 134S1187PKPFESSSSIGAEKP
Site 135S1188KPFESSSSIGAEKPR
Site 136S1206LPEEEVESSRTPWLY
Site 137S1207PEEEVESSRTPWLYE
Site 138T1209EEVESSRTPWLYEQE
Site 139Y1213SSRTPWLYEQEGEVE
Site 140S1229PFIKTGFSVSVEKST
Site 141S1231IKTGFSVSVEKSTSS
Site 142S1235FSVSVEKSTSSNRKN
Site 143S1237VSVEKSTSSNRKNQL
Site 144S1238SVEKSTSSNRKNQLD
Site 145T1246NRKNQLDTNGRRRQF
Site 146S1257RRQFDEESLESFSSM
Site 147S1260FDEESLESFSSMPDP
Site 148S1262EESLESFSSMPDPVD
Site 149S1263ESLESFSSMPDPVDP
Site 150T1271MPDPVDPTTVTKTFK
Site 151T1272PDPVDPTTVTKTFKT
Site 152T1274PVDPTTVTKTFKTRK
Site 153T1276DPTTVTKTFKTRKAS
Site 154S1283TFKTRKASAQASLAS
Site 155S1287RKASAQASLASKDKT
Site 156S1290SAQASLASKDKTPKS
Site 157T1294SLASKDKTPKSKSKK
Site 158S1297SKDKTPKSKSKKRNS
Site 159S1299DKTPKSKSKKRNSTQ
Site 160S1304SKSKKRNSTQLKSRV
Site 161T1305KSKKRNSTQLKSRVK
Site 162S1309RNSTQLKSRVKNIRY
Site 163Y1316SRVKNIRYESASMSS
Site 164S1318VKNIRYESASMSSTC
Site 165S1320NIRYESASMSSTCEP
Site 166S1322RYESASMSSTCEPCK
Site 167S1323YESASMSSTCEPCKS
Site 168T1324ESASMSSTCEPCKSR
Site 169S1330STCEPCKSRNRHSAQ
Site 170S1335CKSRNRHSAQTEEPV
Site 171T1338RNRHSAQTEEPVQAK
Site 172S1364KIIKCNRSTEISSET
Site 173T1365IIKCNRSTEISSETG
Site 174S1368CNRSTEISSETGSDF
Site 175S1369NRSTEISSETGSDFS
Site 176T1371STEISSETGSDFSMF
Site 177S1373EISSETGSDFSMFEA
Site 178S1376SETGSDFSMFEALRD
Site 179T1391TIYSEVATLISQNES
Site 180S1394SEVATLISQNESRPH
Site 181S1398TLISQNESRPHFLIE
Site 182Y1417LQLLNTDYLRQRALY
Site 183Y1424YLRQRALYALQDIVS
Site 184S1431YALQDIVSRHISESH
Site 185S1435DIVSRHISESHEKGE
Site 186S1437VSRHISESHEKGENV
Site 187S1446EKGENVKSVNSGTWI
Site 188S1449ENVKSVNSGTWIASN
Site 189T1451VKSVNSGTWIASNSE
Site 190S1455NSGTWIASNSELTPS
Site 191S1457GTWIASNSELTPSES
Site 192T1460IASNSELTPSESLAT
Site 193S1462SNSELTPSESLATTD
Site 194S1464SELTPSESLATTDDE
Site 195T1468PSESLATTDDETFEK
Site 196T1472LATTDDETFEKNFER
Site 197T1481EKNFERETHKISEQN
Site 198S1485ERETHKISEQNDADN
Site 199S1494QNDADNASVLSVSSN
Site 200S1497ADNASVLSVSSNFEP
Site 201S1499NASVLSVSSNFEPFA
Site 202S1500ASVLSVSSNFEPFAT
Site 203T1507SNFEPFATDDLGNTV
Site 204T1513ATDDLGNTVIHLDQA
Site 205Y1527ALARMREYERMKTEA
Site 206T1532REYERMKTEAESNSN
Site 207S1538KTEAESNSNMRCTCR
Site 208T1558DGAGAGTTVNNLEET
Site 209T1565TVNNLEETPVIENRS
Site 210S1573PVIENRSSQQPVSEV
Site 211S1578RSSQQPVSEVSTIPC
Site 212S1581QQPVSEVSTIPCPRI
Site 213T1582QPVSEVSTIPCPRID
Site 214T1590IPCPRIDTQQLDRQI
Site 215S1618HMDEVCSSQLLTSVR
Site 216T1630SVRRMVLTLTQQNDE
Site 217T1632RRMVLTLTQQNDESK
Site 218S1656LGSILQDSLAKFAGR
Site 219T1711CKRKIEATGVIQSCA
Site 220S1716EATGVIQSCAKEAKR
Site 221S1730RILEDHGSPAGEIDD
Site 222T1745EDKDKDETETVKQTQ
Site 223T1747KDKDETETVKQTQTS
Site 224Y1757QTQTSEVYDGPKNVR
Site 225S1765DGPKNVRSDISDQEE
Site 226S1768KNVRSDISDQEEDEE
Site 227S1776DQEEDEESEGCPVSI
Site 228S1782ESEGCPVSINLSKAE
Site 229S1786CPVSINLSKAETQAL
Site 230T1790INLSKAETQALTNYG
Site 231T1794KAETQALTNYGSGED
Site 232Y1796ETQALTNYGSGEDEN
Site 233S1798QALTNYGSGEDENED
Site 234T1846LQRDFKKTAESKNVP
Site 235T1859VPLEREATSKNDQNN
Site 236Y1873NCPVKPCYLNILEDE
Site 237S1885EDEQPLNSAAHKESP
Site 238S1891NSAAHKESPPTVDST
Site 239T1894AHKESPPTVDSTQQP
Site 240S1897ESPPTVDSTQQPNPL
Site 241T1898SPPTVDSTQQPNPLP
Site 242S1923PRVKEVKSAQETPES
Site 243T1927EVKSAQETPESSLAG
Site 244S1930SAQETPESSLAGSPD
Site 245S1931AQETPESSLAGSPDT
Site 246S1935PESSLAGSPDTESPV
Site 247T1938SLAGSPDTESPVLVN
Site 248S1940AGSPDTESPVLVNDY
Site 249Y1947SPVLVNDYEAESGNI
Site 250S1951VNDYEAESGNISQKS
Site 251S1955EAESGNISQKSDEED
Site 252S1958SGNISQKSDEEDFVK
Site 253T1974EDLPLKLTIYSEADL
Site 254Y1976LPLKLTIYSEADLRK
Site 255S1977PLKLTIYSEADLRKK
Site 256S1995EEQKNHLSGEICEMQ
Site 257T2018ETLKEPETVGAQSI_
Site 258S2023PETVGAQSI______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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