KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CDK5R1
Full Name:
Cyclin-dependent kinase 5 activator 1
Alias:
CD5R; CD5R1; CDK5 activator 1; CDK5R; Cyclin-dependent kinase 5 regulatory subunit 1; NCK5A; P23; P25; P35; Tau protein kinase II 23 kDa subunit; TPKII regulatory subunit
Type:
Protein kinase, regulatory subunit
Mass (Da):
34060
Number AA:
307
UniProt ID:
Q15078
International Prot ID:
IPI00014316
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030424
GO:0043025
GO:0043292
Uniprot
OncoNet
Molecular Function:
GO:0045296
GO:0005509
GO:0016534
PhosphoSite+
KinaseNET
Biological Process:
GO:0007411
GO:0007413
GO:0007420
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
T
V
L
S
L
S
P
S
Y
R
K
Site 2
S8
M
G
T
V
L
S
L
S
P
S
Y
R
K
A
T
Site 3
T15
S
P
S
Y
R
K
A
T
L
F
E
D
G
A
A
Site 4
Y27
G
A
A
T
V
G
H
Y
T
A
V
Q
N
S
K
Site 5
S33
H
Y
T
A
V
Q
N
S
K
N
A
K
D
K
N
Site 6
S45
D
K
N
L
K
R
H
S
I
I
S
V
L
P
W
Site 7
S48
L
K
R
H
S
I
I
S
V
L
P
W
K
R
I
Site 8
S59
W
K
R
I
V
A
V
S
A
K
K
K
N
S
K
Site 9
S72
S
K
K
V
Q
P
N
S
S
Y
Q
N
N
I
T
Site 10
S73
K
K
V
Q
P
N
S
S
Y
Q
N
N
I
T
H
Site 11
Y74
K
V
Q
P
N
S
S
Y
Q
N
N
I
T
H
L
Site 12
S89
N
N
E
N
L
K
K
S
L
S
C
A
N
L
S
Site 13
S91
E
N
L
K
K
S
L
S
C
A
N
L
S
T
F
Site 14
S96
S
L
S
C
A
N
L
S
T
F
A
Q
P
P
P
Site 15
S112
Q
P
P
A
P
P
A
S
Q
L
S
G
S
Q
T
Site 16
S115
A
P
P
A
S
Q
L
S
G
S
Q
T
G
G
S
Site 17
S117
P
A
S
Q
L
S
G
S
Q
T
G
G
S
S
S
Site 18
T119
S
Q
L
S
G
S
Q
T
G
G
S
S
S
V
K
Site 19
S122
S
G
S
Q
T
G
G
S
S
S
V
K
K
A
P
Site 20
S123
G
S
Q
T
G
G
S
S
S
V
K
K
A
P
H
Site 21
S124
S
Q
T
G
G
S
S
S
V
K
K
A
P
H
P
Site 22
T138
P
A
V
T
S
A
G
T
P
K
R
V
I
V
Q
Site 23
Y164
E
F
L
C
R
R
C
Y
R
L
K
H
L
S
P
Site 24
S170
C
Y
R
L
K
H
L
S
P
T
D
P
V
L
W
Site 25
T172
R
L
K
H
L
S
P
T
D
P
V
L
W
L
R
Site 26
S184
W
L
R
S
V
D
R
S
L
L
L
Q
G
W
Q
Site 27
S213
M
L
C
R
D
V
I
S
S
E
V
G
S
D
H
Site 28
S214
L
C
R
D
V
I
S
S
E
V
G
S
D
H
E
Site 29
S218
V
I
S
S
E
V
G
S
D
H
E
L
Q
A
V
Site 30
S242
S
Y
M
G
N
E
I
S
Y
P
L
K
P
F
L
Site 31
Y281
Q
I
N
A
D
P
H
Y
F
T
Q
V
F
S
D
Site 32
T283
N
A
D
P
H
Y
F
T
Q
V
F
S
D
L
K
Site 33
S287
H
Y
F
T
Q
V
F
S
D
L
K
N
E
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation