KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
EFTUD2
Full Name:
116 kDa U5 small nuclear ribonucleoprotein component
Alias:
KIAA0031; SNRP116; U5 snRNP- specific protein, 116 kDa; U5 snRNP-specific protein, 116 kDa; U5-116 kDa; U5S1
Type:
RNA binding protein
Mass (Da):
109436
Number AA:
972
UniProt ID:
Q15029
International Prot ID:
IPI00003519
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015030
GO:0016607
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
GO:0008380
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
D
T
D
L
Y
D
E
F
G
Site 2
Y6
_
_
M
D
T
D
L
Y
D
E
F
G
N
Y
I
Site 3
Y12
L
Y
D
E
F
G
N
Y
I
G
P
E
L
D
S
Site 4
S19
Y
I
G
P
E
L
D
S
D
E
D
D
D
E
L
Site 5
T30
D
D
E
L
G
R
E
T
K
D
L
D
E
M
D
Site 6
Y65
V
L
H
E
D
K
K
Y
Y
P
T
A
E
E
V
Site 7
Y66
L
H
E
D
K
K
Y
Y
P
T
A
E
E
V
Y
Site 8
Y73
Y
P
T
A
E
E
V
Y
G
P
E
V
E
T
I
Site 9
T79
V
Y
G
P
E
V
E
T
I
V
Q
E
E
D
T
Site 10
T86
T
I
V
Q
E
E
D
T
Q
P
L
T
E
P
I
Site 11
T90
E
E
D
T
Q
P
L
T
E
P
I
I
K
P
V
Site 12
T133
S
E
L
I
R
N
V
T
L
C
G
H
L
H
H
Site 13
Y161
H
P
E
I
R
K
R
Y
D
Q
D
L
C
Y
T
Site 14
Y167
R
Y
D
Q
D
L
C
Y
T
D
I
L
F
T
E
Site 15
T168
Y
D
Q
D
L
C
Y
T
D
I
L
F
T
E
Q
Site 16
S212
T
P
G
H
V
N
F
S
D
E
V
T
A
G
L
Site 17
T216
V
N
F
S
D
E
V
T
A
G
L
R
I
S
D
Site 18
T239
A
E
G
V
M
L
N
T
E
R
L
I
K
H
A
Site 19
T272
L
E
L
K
L
P
P
T
D
A
Y
Y
K
L
R
Site 20
Y275
K
L
P
P
T
D
A
Y
Y
K
L
R
H
I
V
Site 21
Y276
L
P
P
T
D
A
Y
Y
K
L
R
H
I
V
D
Site 22
Y336
D
T
F
G
D
I
N
Y
Q
E
F
A
K
R
L
Site 23
Y348
K
R
L
W
G
D
I
Y
F
N
P
K
T
R
K
Site 24
T353
D
I
Y
F
N
P
K
T
R
K
F
T
K
K
A
Site 25
T357
N
P
K
T
R
K
F
T
K
K
A
P
T
S
S
Site 26
S363
F
T
K
K
A
P
T
S
S
S
Q
R
S
F
V
Site 27
S364
T
K
K
A
P
T
S
S
S
Q
R
S
F
V
E
Site 28
S365
K
K
A
P
T
S
S
S
Q
R
S
F
V
E
F
Site 29
S368
P
T
S
S
S
Q
R
S
F
V
E
F
I
L
E
Site 30
T390
Q
V
V
G
D
V
D
T
S
L
P
R
T
L
D
Site 31
S391
V
V
G
D
V
D
T
S
L
P
R
T
L
D
E
Site 32
T395
V
D
T
S
L
P
R
T
L
D
E
L
G
I
H
Site 33
T404
D
E
L
G
I
H
L
T
K
E
E
L
K
L
N
Site 34
S440
M
C
V
Q
H
I
P
S
P
K
V
G
A
K
P
Site 35
T454
P
K
I
E
H
T
Y
T
G
G
V
D
S
D
L
Site 36
S459
T
Y
T
G
G
V
D
S
D
L
G
E
A
M
S
Site 37
S466
S
D
L
G
E
A
M
S
D
C
D
P
D
G
P
Site 38
T515
K
V
L
G
E
N
Y
T
L
E
D
E
E
D
S
Site 39
S522
T
L
E
D
E
E
D
S
Q
I
C
T
V
G
R
Site 40
T526
E
E
D
S
Q
I
C
T
V
G
R
L
W
I
S
Site 41
S533
T
V
G
R
L
W
I
S
V
A
R
Y
H
I
E
Site 42
T562
V
D
Q
P
I
V
K
T
A
T
I
T
E
P
R
Site 43
T585
R
P
L
K
F
N
T
T
S
V
I
K
I
A
V
Site 44
S598
A
V
E
P
V
N
P
S
E
L
P
K
M
L
D
Site 45
S613
G
L
R
K
V
N
K
S
Y
P
S
L
T
T
K
Site 46
Y614
L
R
K
V
N
K
S
Y
P
S
L
T
T
K
V
Site 47
T618
N
K
S
Y
P
S
L
T
T
K
V
E
E
S
G
Site 48
Y648
M
H
D
L
R
K
M
Y
S
E
I
D
I
K
V
Site 49
S649
H
D
L
R
K
M
Y
S
E
I
D
I
K
V
A
Site 50
S671
E
T
V
V
E
T
S
S
L
K
C
F
A
E
T
Site 51
T678
S
L
K
C
F
A
E
T
P
N
K
K
N
K
I
Site 52
Y722
G
E
F
F
Q
T
K
Y
D
W
D
L
L
A
A
Site 53
T749
P
N
I
L
V
D
D
T
L
P
S
E
V
D
K
Site 54
T811
G
G
G
Q
I
I
P
T
A
R
R
V
V
Y
S
Site 55
Y831
T
P
R
L
M
E
P
Y
Y
F
V
E
V
Q
A
Site 56
Y832
P
R
L
M
E
P
Y
Y
F
V
E
V
Q
A
P
Site 57
T858
A
R
R
R
G
H
V
T
Q
D
A
P
I
P
G
Site 58
S866
Q
D
A
P
I
P
G
S
P
L
Y
T
I
K
A
Site 59
T889
G
F
E
T
D
L
R
T
H
T
Q
G
Q
A
F
Site 60
T891
E
T
D
L
R
T
H
T
Q
G
Q
A
F
S
L
Site 61
S915
P
G
D
P
L
D
K
S
I
V
I
R
P
L
E
Site 62
T937
A
R
E
F
M
I
K
T
R
R
R
K
G
L
S
Site 63
S944
T
R
R
R
K
G
L
S
E
D
V
S
I
S
K
Site 64
S948
K
G
L
S
E
D
V
S
I
S
K
F
F
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation