PhosphoNET

           
Protein Info 
   
Short Name:  PUM1
Full Name:  Pumilio homolog 1
Alias:  KIAA0099; PUMH; PUMH1; Pumilio 1; PUML1
Type:  RNA binding protein
Mass (Da):  126473
Number AA:  1186
UniProt ID:  Q14671
International Prot ID:  IPI00646054
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829     Uniprot OncoNet
Molecular Function:  GO:0003723     PhosphoSite+ KinaseNET
Biological Process:  GO:0016044  GO:0006892  GO:0006417 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S17KAVLWQDSFSPHLKH
Site 2S19VLWQDSFSPHLKHHP
Site 3T39PNMPVVLTSGTGSQA
Site 4S40NMPVVLTSGTGSQAQ
Site 5S44VLTSGTGSQAQPQPA
Site 6S68HSSPVPGSIGVAGRS
Site 7S75SIGVAGRSQDDAMVD
Site 8Y83QDDAMVDYFFQRQHG
Site 9S98EQLGGGGSGGGGYNN
Site 10Y103GGSGGGGYNNSKHRW
Site 11S106GGGGYNNSKHRWPTG
Site 12T112NSKHRWPTGDNIHAE
Site 13S124HAEHQVRSMDELNHD
Site 14T155PGKKFWETDESSKDG
Site 15S158KFWETDESSKDGPKG
Site 16T179WRDSAWGTSDHSVSQ
Site 17S180RDSAWGTSDHSVSQP
Site 18S183AWGTSDHSVSQPIMV
Site 19S185GTSDHSVSQPIMVQR
Site 20S197VQRRPGQSFHVNSEV
Site 21S202GQSFHVNSEVNSVLS
Site 22S206HVNSEVNSVLSPRSE
Site 23S209SEVNSVLSPRSESGG
Site 24S212NSVLSPRSESGGLGV
Site 25S227SMVEYVLSSSPGDSC
Site 26S228MVEYVLSSSPGDSCL
Site 27S229VEYVLSSSPGDSCLR
Site 28S233LSSSPGDSCLRKGGF
Site 29S247FGPRDADSDENDKGE
Site 30T260GEKKNKGTFDGDKLG
Site 31T279EGDVMDKTNGLPVQN
Site 32S296DADVKDFSRTPGNCQ
Site 33T298DVKDFSRTPGNCQNS
Site 34S305TPGNCQNSANEVDLL
Site 35S319LGPNQNGSEGLAQLT
Site 36S327EGLAQLTSTNGAKPV
Site 37S338AKPVEDFSNMESQSV
Site 38S342EDFSNMESQSVPLDP
Site 39S344FSNMESQSVPLDPME
Site 40Y362MEPLQFDYSGTQVPV
Site 41S363EPLQFDYSGTQVPVD
Site 42T365LQFDYSGTQVPVDSA
Site 43Y381ATVGLFDYNSQQQLF
Site 44S383VGLFDYNSQQQLFQR
Site 45S432VPNPYIISAAPPGTD
Site 46Y460PAVVPHQYYGVTPWG
Site 47T464PHQYYGVTPWGVYPA
Site 48S472PWGVYPASLFQQQAA
Site 49T493NSANQQTTPQAQQGQ
Site 50S509QVLRGGASQRPLTPN
Site 51T514GASQRPLTPNQNQQG
Site 52T616AGGLAGTTNGPFRPL
Site 53T625GPFRPLGTQQPQPQP
Site 54S642QPNNNLASSSFYGNN
Site 55S644NNNLASSSFYGNNSL
Site 56Y646NLASSSFYGNNSLNS
Site 57S650SSFYGNNSLNSNSQS
Site 58S653YGNNSLNSNSQSSSL
Site 59S655NNSLNSNSQSSSLFS
Site 60S657SLNSNSQSSSLFSQG
Site 61S658LNSNSQSSSLFSQGS
Site 62S659NSNSQSSSLFSQGSA
Site 63S662SQSSSLFSQGSAQPA
Site 64S665SSLFSQGSAQPANTS
Site 65S672SAQPANTSLGFGSSS
Site 66S677NTSLGFGSSSSLGAT
Site 67S699FGTAVANSNTGSGSR
Site 68T701TAVANSNTGSGSRRD
Site 69S703VANSNTGSGSRRDSL
Site 70S705NSNTGSGSRRDSLTG
Site 71S709GSGSRRDSLTGSSDL
Site 72T711GSRRDSLTGSSDLYK
Site 73S713RRDSLTGSSDLYKRT
Site 74S714RDSLTGSSDLYKRTS
Site 75Y717LTGSSDLYKRTSSSL
Site 76T720SSDLYKRTSSSLTPI
Site 77S721SDLYKRTSSSLTPIG
Site 78S722DLYKRTSSSLTPIGH
Site 79S723LYKRTSSSLTPIGHS
Site 80T725KRTSSSLTPIGHSFY
Site 81Y732TPIGHSFYNGLSFSS
Site 82S736HSFYNGLSFSSSPGP
Site 83S738FYNGLSFSSSPGPVG
Site 84S740NGLSFSSSPGPVGMP
Site 85S750PVGMPLPSQGPGHSQ
Site 86S756PSQGPGHSQTPPPSL
Site 87T758QGPGHSQTPPPSLSS
Site 88S762HSQTPPPSLSSHGSS
Site 89S764QTPPPSLSSHGSSSS
Site 90S765TPPPSLSSHGSSSSL
Site 91S768PSLSSHGSSSSLNLG
Site 92S769SLSSHGSSSSLNLGG
Site 93S770LSSHGSSSSLNLGGL
Site 94S771SSHGSSSSLNLGGLT
Site 95S781LGGLTNGSGRYISAA
Site 96S786NGSGRYISAAPGAEA
Site 97Y795APGAEAKYRSASSAS
Site 98S797GAEAKYRSASSASSL
Site 99S799EAKYRSASSASSLFS
Site 100S800AKYRSASSASSLFSP
Site 101S802YRSASSASSLFSPSS
Site 102S803RSASSASSLFSPSST
Site 103S806SSASSLFSPSSTLFS
Site 104S808ASSLFSPSSTLFSSS
Site 105S809SSLFSPSSTLFSSSR
Site 106T810SLFSPSSTLFSSSRL
Site 107S813SPSSTLFSSSRLRYG
Site 108S814PSSTLFSSSRLRYGM
Site 109S815SSTLFSSSRLRYGMS
Site 110Y819FSSSRLRYGMSDVMP
Site 111S822SRLRYGMSDVMPSGR
Site 112S827GMSDVMPSGRSRLLE
Site 113Y841EDFRNNRYPNLQLRE
Site 114S857AGHIMEFSQDQHGSR
Site 115T874QLKLERATPAERQLV
Site 116S910QKFFEFGSLEQKLAL
Site 117S947KALEFIPSDQQNEMV
Site 118S1001KGQVFALSTHPYGCR
Site 119Y1005FALSTHPYGCRVIQR
Site 120T1022EHCLPDQTLPILEEL
Site 121Y1041EQLVQDQYGNYVIQH
Site 122Y1044VQDQYGNYVIQHVLE
Site 123S1059HGRPEDKSKIVAEIR
Site 124S1073RGNVLVLSQHKFASN
Site 125T1087NVVEKCVTHASRTER
Site 126T1092CVTHASRTERAVLID
Site 127Y1113DGPHSALYTMMKDQY
Site 128T1114GPHSALYTMMKDQYA
Site 129Y1120YTMMKDQYANYVVQK
Site 130Y1123MKDQYANYVVQKMID
Site 131T1150KIRPHIATLRKYTYG
Site 132Y1154HIATLRKYTYGKHIL
Site 133T1155IATLRKYTYGKHILA
Site 134Y1156ATLRKYTYGKHILAK
Site 135Y1167ILAKLEKYYMKNGVD
Site 136Y1168LAKLEKYYMKNGVDL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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