KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
UBAP2L
Full Name:
Ubiquitin-associated protein 2-like
Alias:
KIAA0144; NICE-4; Protein NICE-4; Ubiquitin associated protein 2-like; Ubiquitin-associated protein 2-like; UBP2L
Type:
Ubiquitin conjugating system
Mass (Da):
114535
Number AA:
1087
UniProt ID:
Q14157
International Prot ID:
IPI00514856
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S43
I
R
L
A
Q
M
I
S
D
H
N
D
A
D
F
Site 2
T93
L
L
E
G
N
P
D
T
H
S
W
E
M
V
G
Site 3
S95
E
G
N
P
D
T
H
S
W
E
M
V
G
K
K
Site 4
S106
V
G
K
K
K
G
V
S
G
Q
K
D
G
G
Q
Site 5
S116
K
D
G
G
Q
T
E
S
N
E
E
G
K
E
N
Site 6
Y130
N
R
D
R
D
R
D
Y
S
R
R
R
G
G
P
Site 7
S131
R
D
R
D
R
D
Y
S
R
R
R
G
G
P
P
Site 8
S145
P
R
R
G
R
G
A
S
R
G
R
E
F
R
G
Site 9
T160
Q
E
N
G
L
D
G
T
K
S
G
G
P
S
G
Site 10
S162
N
G
L
D
G
T
K
S
G
G
P
S
G
R
G
Site 11
S166
G
T
K
S
G
G
P
S
G
R
G
T
E
R
G
Site 12
T170
G
G
P
S
G
R
G
T
E
R
G
R
R
G
R
Site 13
S184
R
G
R
G
R
G
G
S
G
R
R
G
G
R
F
Site 14
S192
G
R
R
G
G
R
F
S
A
Q
G
M
G
T
F
Site 15
T198
F
S
A
Q
G
M
G
T
F
N
P
A
D
Y
A
Site 16
Y204
G
T
F
N
P
A
D
Y
A
E
P
A
N
T
D
Site 17
T210
D
Y
A
E
P
A
N
T
D
D
N
Y
G
N
S
Site 18
Y214
P
A
N
T
D
D
N
Y
G
N
S
S
G
N
T
Site 19
T234
H
F
E
P
D
D
G
T
S
A
W
R
T
A
T
Site 20
T239
D
G
T
S
A
W
R
T
A
T
E
E
W
G
T
Site 21
T241
T
S
A
W
R
T
A
T
E
E
W
G
T
E
D
Site 22
T246
T
A
T
E
E
W
G
T
E
D
W
N
E
D
L
Site 23
S254
E
D
W
N
E
D
L
S
E
T
K
I
F
T
A
Site 24
S266
F
T
A
S
N
V
S
S
V
P
L
P
A
E
N
Site 25
T291
L
A
V
L
L
G
K
T
P
S
T
M
E
N
D
Site 26
S293
V
L
L
G
K
T
P
S
T
M
E
N
D
S
S
Site 27
T294
L
L
G
K
T
P
S
T
M
E
N
D
S
S
N
Site 28
S299
P
S
T
M
E
N
D
S
S
N
L
D
P
S
Q
Site 29
S300
S
T
M
E
N
D
S
S
N
L
D
P
S
Q
A
Site 30
S305
D
S
S
N
L
D
P
S
Q
A
P
S
L
A
Q
Site 31
S319
Q
P
L
V
F
S
N
S
K
Q
T
A
I
S
Q
Site 32
S325
N
S
K
Q
T
A
I
S
Q
P
A
S
G
N
T
Site 33
S329
T
A
I
S
Q
P
A
S
G
N
T
F
S
H
H
Site 34
T332
S
Q
P
A
S
G
N
T
F
S
H
H
S
M
V
Site 35
S334
P
A
S
G
N
T
F
S
H
H
S
M
V
S
M
Site 36
S337
G
N
T
F
S
H
H
S
M
V
S
M
L
G
K
Site 37
S356
V
G
E
A
K
G
G
S
T
T
G
S
Q
F
L
Site 38
S360
K
G
G
S
T
T
G
S
Q
F
L
E
Q
F
K
Site 39
T368
Q
F
L
E
Q
F
K
T
A
Q
A
L
A
Q
L
Site 40
S380
A
Q
L
A
A
Q
H
S
Q
S
G
S
T
T
T
Site 41
S382
L
A
A
Q
H
S
Q
S
G
S
T
T
T
S
S
Site 42
S384
A
Q
H
S
Q
S
G
S
T
T
T
S
S
W
D
Site 43
T386
H
S
Q
S
G
S
T
T
T
S
S
W
D
M
G
Site 44
S388
Q
S
G
S
T
T
T
S
S
W
D
M
G
S
T
Site 45
S389
S
G
S
T
T
T
S
S
W
D
M
G
S
T
T
Site 46
S394
T
S
S
W
D
M
G
S
T
T
Q
S
P
S
L
Site 47
T396
S
W
D
M
G
S
T
T
Q
S
P
S
L
V
Q
Site 48
S398
D
M
G
S
T
T
Q
S
P
S
L
V
Q
Y
D
Site 49
S400
G
S
T
T
Q
S
P
S
L
V
Q
Y
D
L
K
Site 50
Y404
Q
S
P
S
L
V
Q
Y
D
L
K
N
P
S
D
Site 51
S410
Q
Y
D
L
K
N
P
S
D
S
A
V
H
S
P
Site 52
S412
D
L
K
N
P
S
D
S
A
V
H
S
P
F
T
Site 53
S416
P
S
D
S
A
V
H
S
P
F
T
K
R
Q
A
Site 54
T419
S
A
V
H
S
P
F
T
K
R
Q
A
F
T
P
Site 55
T425
F
T
K
R
Q
A
F
T
P
S
S
T
M
M
E
Site 56
S427
K
R
Q
A
F
T
P
S
S
T
M
M
E
V
F
Site 57
T429
Q
A
F
T
P
S
S
T
M
M
E
V
F
L
Q
Site 58
S439
E
V
F
L
Q
E
K
S
P
A
V
A
T
S
T
Site 59
T444
E
K
S
P
A
V
A
T
S
T
A
A
P
P
P
Site 60
S445
K
S
P
A
V
A
T
S
T
A
A
P
P
P
P
Site 61
T446
S
P
A
V
A
T
S
T
A
A
P
P
P
P
S
Site 62
S453
T
A
A
P
P
P
P
S
S
P
L
P
S
K
S
Site 63
S454
A
A
P
P
P
P
S
S
P
L
P
S
K
S
T
Site 64
S458
P
P
S
S
P
L
P
S
K
S
T
S
A
P
Q
Site 65
S460
S
S
P
L
P
S
K
S
T
S
A
P
Q
M
S
Site 66
T461
S
P
L
P
S
K
S
T
S
A
P
Q
M
S
P
Site 67
S462
P
L
P
S
K
S
T
S
A
P
Q
M
S
P
G
Site 68
S467
S
T
S
A
P
Q
M
S
P
G
S
S
D
N
Q
Site 69
S470
A
P
Q
M
S
P
G
S
S
D
N
Q
S
S
S
Site 70
S471
P
Q
M
S
P
G
S
S
D
N
Q
S
S
S
P
Site 71
S475
P
G
S
S
D
N
Q
S
S
S
P
Q
P
A
Q
Site 72
S476
G
S
S
D
N
Q
S
S
S
P
Q
P
A
Q
Q
Site 73
S477
S
S
D
N
Q
S
S
S
P
Q
P
A
Q
Q
K
Site 74
S493
K
Q
Q
K
K
K
A
S
L
T
S
K
I
P
A
Site 75
T495
Q
K
K
K
A
S
L
T
S
K
I
P
A
L
A
Site 76
S496
K
K
K
A
S
L
T
S
K
I
P
A
L
A
V
Site 77
S530
F
G
S
E
P
V
L
S
D
Y
E
S
T
P
T
Site 78
Y532
S
E
P
V
L
S
D
Y
E
S
T
P
T
T
S
Site 79
S534
P
V
L
S
D
Y
E
S
T
P
T
T
S
A
S
Site 80
T535
V
L
S
D
Y
E
S
T
P
T
T
S
A
S
S
Site 81
T537
S
D
Y
E
S
T
P
T
T
S
A
S
S
S
Q
Site 82
T538
D
Y
E
S
T
P
T
T
S
A
S
S
S
Q
A
Site 83
S539
Y
E
S
T
P
T
T
S
A
S
S
S
Q
A
P
Site 84
S541
S
T
P
T
T
S
A
S
S
S
Q
A
P
S
S
Site 85
S543
P
T
T
S
A
S
S
S
Q
A
P
S
S
L
Y
Site 86
S547
A
S
S
S
Q
A
P
S
S
L
Y
T
S
T
A
Site 87
S548
S
S
S
Q
A
P
S
S
L
Y
T
S
T
A
S
Site 88
Y550
S
Q
A
P
S
S
L
Y
T
S
T
A
S
E
S
Site 89
T551
Q
A
P
S
S
L
Y
T
S
T
A
S
E
S
S
Site 90
S552
A
P
S
S
L
Y
T
S
T
A
S
E
S
S
S
Site 91
T553
P
S
S
L
Y
T
S
T
A
S
E
S
S
S
T
Site 92
S555
S
L
Y
T
S
T
A
S
E
S
S
S
T
I
S
Site 93
S557
Y
T
S
T
A
S
E
S
S
S
T
I
S
S
N
Site 94
S558
T
S
T
A
S
E
S
S
S
T
I
S
S
N
Q
Site 95
S559
S
T
A
S
E
S
S
S
T
I
S
S
N
Q
S
Site 96
T560
T
A
S
E
S
S
S
T
I
S
S
N
Q
S
Q
Site 97
S562
S
E
S
S
S
T
I
S
S
N
Q
S
Q
E
S
Site 98
S563
E
S
S
S
T
I
S
S
N
Q
S
Q
E
S
G
Site 99
S566
S
T
I
S
S
N
Q
S
Q
E
S
G
Y
Q
S
Site 100
S569
S
S
N
Q
S
Q
E
S
G
Y
Q
S
G
P
I
Site 101
Y571
N
Q
S
Q
E
S
G
Y
Q
S
G
P
I
Q
S
Site 102
S573
S
Q
E
S
G
Y
Q
S
G
P
I
Q
S
T
T
Site 103
S578
Y
Q
S
G
P
I
Q
S
T
T
Y
T
S
Q
N
Site 104
T579
Q
S
G
P
I
Q
S
T
T
Y
T
S
Q
N
N
Site 105
T580
S
G
P
I
Q
S
T
T
Y
T
S
Q
N
N
A
Site 106
Y581
G
P
I
Q
S
T
T
Y
T
S
Q
N
N
A
Q
Site 107
T582
P
I
Q
S
T
T
Y
T
S
Q
N
N
A
Q
G
Site 108
Y592
N
N
A
Q
G
P
L
Y
E
Q
R
S
T
Q
T
Site 109
T597
P
L
Y
E
Q
R
S
T
Q
T
R
R
Y
P
S
Site 110
Y602
R
S
T
Q
T
R
R
Y
P
S
S
I
S
S
S
Site 111
S604
T
Q
T
R
R
Y
P
S
S
I
S
S
S
P
Q
Site 112
S605
Q
T
R
R
Y
P
S
S
I
S
S
S
P
Q
K
Site 113
S607
R
R
Y
P
S
S
I
S
S
S
P
Q
K
D
L
Site 114
S608
R
Y
P
S
S
I
S
S
S
P
Q
K
D
L
T
Site 115
S609
Y
P
S
S
I
S
S
S
P
Q
K
D
L
T
Q
Site 116
T615
S
S
P
Q
K
D
L
T
Q
A
K
N
G
F
S
Site 117
T627
G
F
S
S
V
Q
A
T
Q
L
Q
T
T
Q
S
Site 118
S634
T
Q
L
Q
T
T
Q
S
V
E
G
A
T
G
S
Site 119
S641
S
V
E
G
A
T
G
S
A
V
K
S
D
S
P
Site 120
S645
A
T
G
S
A
V
K
S
D
S
P
S
T
S
S
Site 121
S647
G
S
A
V
K
S
D
S
P
S
T
S
S
I
P
Site 122
S649
A
V
K
S
D
S
P
S
T
S
S
I
P
P
L
Site 123
S651
K
S
D
S
P
S
T
S
S
I
P
P
L
N
E
Site 124
S652
S
D
S
P
S
T
S
S
I
P
P
L
N
E
T
Site 125
T668
S
A
A
S
L
L
T
T
T
N
Q
H
S
S
S
Site 126
T669
A
A
S
L
L
T
T
T
N
Q
H
S
S
S
L
Site 127
S673
L
T
T
T
N
Q
H
S
S
S
L
G
G
L
S
Site 128
S675
T
T
N
Q
H
S
S
S
L
G
G
L
S
H
S
Site 129
S680
S
S
S
L
G
G
L
S
H
S
E
E
I
P
N
Site 130
S682
S
L
G
G
L
S
H
S
E
E
I
P
N
T
T
Site 131
T688
H
S
E
E
I
P
N
T
T
T
T
Q
H
S
S
Site 132
T690
E
E
I
P
N
T
T
T
T
Q
H
S
S
T
L
Site 133
T691
E
I
P
N
T
T
T
T
Q
H
S
S
T
L
S
Site 134
S694
N
T
T
T
T
Q
H
S
S
T
L
S
T
Q
Q
Site 135
S698
T
Q
H
S
S
T
L
S
T
Q
Q
N
T
L
S
Site 136
T699
Q
H
S
S
T
L
S
T
Q
Q
N
T
L
S
S
Site 137
T703
T
L
S
T
Q
Q
N
T
L
S
S
S
T
S
S
Site 138
S705
S
T
Q
Q
N
T
L
S
S
S
T
S
S
G
R
Site 139
S706
T
Q
Q
N
T
L
S
S
S
T
S
S
G
R
T
Site 140
S707
Q
Q
N
T
L
S
S
S
T
S
S
G
R
T
S
Site 141
S709
N
T
L
S
S
S
T
S
S
G
R
T
S
T
S
Site 142
S710
T
L
S
S
S
T
S
S
G
R
T
S
T
S
T
Site 143
T713
S
S
T
S
S
G
R
T
S
T
S
T
L
L
H
Site 144
S714
S
T
S
S
G
R
T
S
T
S
T
L
L
H
T
Site 145
T715
T
S
S
G
R
T
S
T
S
T
L
L
H
T
S
Site 146
S716
S
S
G
R
T
S
T
S
T
L
L
H
T
S
V
Site 147
T717
S
G
R
T
S
T
S
T
L
L
H
T
S
V
E
Site 148
T721
S
T
S
T
L
L
H
T
S
V
E
S
E
A
N
Site 149
S731
E
S
E
A
N
L
H
S
S
S
S
T
F
S
T
Site 150
S732
S
E
A
N
L
H
S
S
S
S
T
F
S
T
T
Site 151
S733
E
A
N
L
H
S
S
S
S
T
F
S
T
T
S
Site 152
S734
A
N
L
H
S
S
S
S
T
F
S
T
T
S
S
Site 153
T735
N
L
H
S
S
S
S
T
F
S
T
T
S
S
T
Site 154
S737
H
S
S
S
S
T
F
S
T
T
S
S
T
V
S
Site 155
T738
S
S
S
S
T
F
S
T
T
S
S
T
V
S
A
Site 156
T739
S
S
S
T
F
S
T
T
S
S
T
V
S
A
P
Site 157
S740
S
S
T
F
S
T
T
S
S
T
V
S
A
P
P
Site 158
S741
S
T
F
S
T
T
S
S
T
V
S
A
P
P
P
Site 159
T742
T
F
S
T
T
S
S
T
V
S
A
P
P
P
V
Site 160
S744
S
T
T
S
S
T
V
S
A
P
P
P
V
V
S
Site 161
S751
S
A
P
P
P
V
V
S
V
S
S
S
L
N
S
Site 162
S753
P
P
P
V
V
S
V
S
S
S
L
N
S
G
S
Site 163
S754
P
P
V
V
S
V
S
S
S
L
N
S
G
S
S
Site 164
S758
S
V
S
S
S
L
N
S
G
S
S
L
G
L
S
Site 165
S760
S
S
S
L
N
S
G
S
S
L
G
L
S
L
G
Site 166
S761
S
S
L
N
S
G
S
S
L
G
L
S
L
G
S
Site 167
S770
G
L
S
L
G
S
N
S
T
V
T
A
S
T
R
Site 168
T771
L
S
L
G
S
N
S
T
V
T
A
S
T
R
S
Site 169
T773
L
G
S
N
S
T
V
T
A
S
T
R
S
S
V
Site 170
S775
S
N
S
T
V
T
A
S
T
R
S
S
V
A
T
Site 171
S779
V
T
A
S
T
R
S
S
V
A
T
T
S
G
K
Site 172
T782
S
T
R
S
S
V
A
T
T
S
G
K
A
P
P
Site 173
T783
T
R
S
S
V
A
T
T
S
G
K
A
P
P
N
Site 174
S784
R
S
S
V
A
T
T
S
G
K
A
P
P
N
L
Site 175
Y813
A
P
G
L
L
H
A
Y
P
P
Q
V
Y
G
Y
Site 176
T828
D
D
L
Q
M
L
Q
T
R
F
P
L
D
Y
Y
Site 177
Y834
Q
T
R
F
P
L
D
Y
Y
S
I
P
F
P
T
Site 178
Y835
T
R
F
P
L
D
Y
Y
S
I
P
F
P
T
P
Site 179
S836
R
F
P
L
D
Y
Y
S
I
P
F
P
T
P
T
Site 180
T841
Y
Y
S
I
P
F
P
T
P
T
T
P
L
T
G
Site 181
T843
S
I
P
F
P
T
P
T
T
P
L
T
G
R
D
Site 182
T844
I
P
F
P
T
P
T
T
P
L
T
G
R
D
G
Site 183
T847
P
T
P
T
T
P
L
T
G
R
D
G
S
L
A
Site 184
S852
P
L
T
G
R
D
G
S
L
A
S
N
P
Y
S
Site 185
S855
G
R
D
G
S
L
A
S
N
P
Y
S
G
D
L
Site 186
Y858
G
S
L
A
S
N
P
Y
S
G
D
L
T
K
F
Site 187
S859
S
L
A
S
N
P
Y
S
G
D
L
T
K
F
G
Site 188
T863
N
P
Y
S
G
D
L
T
K
F
G
R
G
D
A
Site 189
S871
K
F
G
R
G
D
A
S
S
P
A
P
A
T
T
Site 190
S872
F
G
R
G
D
A
S
S
P
A
P
A
T
T
L
Site 191
T877
A
S
S
P
A
P
A
T
T
L
A
Q
P
Q
Q
Site 192
Y906
N
P
A
L
P
P
G
Y
S
Y
T
S
L
P
Y
Site 193
S907
P
A
L
P
P
G
Y
S
Y
T
S
L
P
Y
Y
Site 194
T909
L
P
P
G
Y
S
Y
T
S
L
P
Y
Y
T
G
Site 195
S910
P
P
G
Y
S
Y
T
S
L
P
Y
Y
T
G
V
Site 196
Y913
Y
S
Y
T
S
L
P
Y
Y
T
G
V
P
G
L
Site 197
Y914
S
Y
T
S
L
P
Y
Y
T
G
V
P
G
L
P
Site 198
T915
Y
T
S
L
P
Y
Y
T
G
V
P
G
L
P
S
Site 199
S922
T
G
V
P
G
L
P
S
T
F
Q
Y
G
P
A
Site 200
S937
V
F
P
V
A
P
T
S
S
K
Q
H
G
V
N
Site 201
S946
K
Q
H
G
V
N
V
S
V
N
A
S
A
T
P
Site 202
S950
V
N
V
S
V
N
A
S
A
T
P
F
Q
Q
P
Site 203
T952
V
S
V
N
A
S
A
T
P
F
Q
Q
P
S
G
Site 204
S958
A
T
P
F
Q
Q
P
S
G
Y
G
S
H
G
Y
Site 205
Y960
P
F
Q
Q
P
S
G
Y
G
S
H
G
Y
N
T
Site 206
S962
Q
Q
P
S
G
Y
G
S
H
G
Y
N
T
G
V
Site 207
Y965
S
G
Y
G
S
H
G
Y
N
T
G
V
S
V
T
Site 208
S970
H
G
Y
N
T
G
V
S
V
T
S
S
N
T
G
Site 209
S984
G
V
P
D
I
S
G
S
V
Y
S
K
T
Q
Q
Site 210
Y986
P
D
I
S
G
S
V
Y
S
K
T
Q
Q
S
F
Site 211
S987
D
I
S
G
S
V
Y
S
K
T
Q
Q
S
F
E
Site 212
T989
S
G
S
V
Y
S
K
T
Q
Q
S
F
E
K
Q
Site 213
S992
V
Y
S
K
T
Q
Q
S
F
E
K
Q
G
F
H
Site 214
S1000
F
E
K
Q
G
F
H
S
G
T
P
A
A
S
F
Site 215
T1002
K
Q
G
F
H
S
G
T
P
A
A
S
F
N
L
Site 216
S1006
H
S
G
T
P
A
A
S
F
N
L
P
S
A
L
Site 217
S1015
N
L
P
S
A
L
G
S
G
G
P
I
N
P
A
Site 218
Y1027
N
P
A
T
A
A
A
Y
P
P
A
P
F
M
H
Site 219
T1037
A
P
F
M
H
I
L
T
P
H
Q
Q
P
H
S
Site 220
S1059
Q
Q
D
G
Q
T
G
S
G
Q
R
S
Q
T
S
Site 221
S1063
Q
T
G
S
G
Q
R
S
Q
T
S
S
I
P
Q
Site 222
T1065
G
S
G
Q
R
S
Q
T
S
S
I
P
Q
K
P
Site 223
S1067
G
Q
R
S
Q
T
S
S
I
P
Q
K
P
Q
T
Site 224
T1074
S
I
P
Q
K
P
Q
T
N
K
S
A
Y
N
S
Site 225
S1077
Q
K
P
Q
T
N
K
S
A
Y
N
S
Y
S
W
Site 226
Y1079
P
Q
T
N
K
S
A
Y
N
S
Y
S
W
G
A
Site 227
Y1082
N
K
S
A
Y
N
S
Y
S
W
G
A
N
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation