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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DAG1
Full Name:
Dystroglycan
Alias:
Alpha-dystroglycan; Beta-dystroglycan; Dystrophin-associated glycoprotein 1
Type:
Cytoskeletal protein
Mass (Da):
97441
Number AA:
895
UniProt ID:
Q14118
International Prot ID:
IPI00028911
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000267
GO:0005576
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0002009
GO:0002011
GO:0003008
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
L
S
V
V
M
A
Q
S
H
W
P
S
E
P
S
Site 2
S33
M
A
Q
S
H
W
P
S
E
P
S
E
A
V
R
Site 3
S36
S
H
W
P
S
E
P
S
E
A
V
R
D
W
E
Site 4
S49
W
E
N
Q
L
E
A
S
M
H
S
V
L
S
D
Site 5
S52
Q
L
E
A
S
M
H
S
V
L
S
D
L
H
E
Site 6
S106
A
G
K
E
A
L
P
S
W
L
H
W
D
S
Q
Site 7
S112
P
S
W
L
H
W
D
S
Q
S
H
T
L
E
G
Site 8
T116
H
W
D
S
Q
S
H
T
L
E
G
L
P
L
D
Site 9
T124
L
E
G
L
P
L
D
T
D
K
G
V
H
Y
I
Site 10
Y130
D
T
D
K
G
V
H
Y
I
S
V
S
A
T
R
Site 11
S132
D
K
G
V
H
Y
I
S
V
S
A
T
R
L
G
Site 12
T136
H
Y
I
S
V
S
A
T
R
L
G
A
N
G
S
Site 13
S143
T
R
L
G
A
N
G
S
H
I
P
Q
T
S
S
Site 14
T148
N
G
S
H
I
P
Q
T
S
S
V
F
S
I
E
Site 15
S150
S
H
I
P
Q
T
S
S
V
F
S
I
E
V
Y
Site 16
S153
P
Q
T
S
S
V
F
S
I
E
V
Y
P
E
D
Site 17
Y157
S
V
F
S
I
E
V
Y
P
E
D
H
S
E
L
Site 18
S162
E
V
Y
P
E
D
H
S
E
L
Q
S
V
R
T
Site 19
S166
E
D
H
S
E
L
Q
S
V
R
T
A
S
P
D
Site 20
T169
S
E
L
Q
S
V
R
T
A
S
P
D
P
G
E
Site 21
S171
L
Q
S
V
R
T
A
S
P
D
P
G
E
V
V
Site 22
S180
D
P
G
E
V
V
S
S
A
C
A
A
D
E
P
Site 23
T200
V
I
L
D
A
D
L
T
K
M
T
P
K
Q
R
Site 24
T203
D
A
D
L
T
K
M
T
P
K
Q
R
I
D
L
Site 25
S216
D
L
L
H
R
M
R
S
F
S
E
V
E
L
H
Site 26
S218
L
H
R
M
R
S
F
S
E
V
E
L
H
N
M
Site 27
S265
L
S
W
K
L
G
C
S
L
N
Q
N
S
V
P
Site 28
S270
G
C
S
L
N
Q
N
S
V
P
D
I
H
G
V
Site 29
S287
P
A
R
E
G
A
M
S
A
Q
L
G
Y
P
V
Site 30
T317
V
R
R
Q
I
H
A
T
P
T
P
V
T
A
I
Site 31
T319
R
Q
I
H
A
T
P
T
P
V
T
A
I
G
P
Site 32
T329
T
A
I
G
P
P
T
T
A
I
Q
E
P
P
S
Site 33
S336
T
A
I
Q
E
P
P
S
R
I
V
P
T
P
T
Site 34
T341
P
P
S
R
I
V
P
T
P
T
S
P
A
I
A
Site 35
T353
A
I
A
P
P
T
E
T
M
A
P
P
V
R
D
Site 36
T367
D
P
V
P
G
K
P
T
V
T
I
R
T
R
G
Site 37
T369
V
P
G
K
P
T
V
T
I
R
T
R
G
A
I
Site 38
S391
P
I
Q
P
T
R
V
S
E
A
G
T
T
V
P
Site 39
T395
T
R
V
S
E
A
G
T
T
V
P
G
Q
I
R
Site 40
T396
R
V
S
E
A
G
T
T
V
P
G
Q
I
R
P
Site 41
T418
V
E
P
T
A
V
A
T
P
P
T
T
T
T
K
Site 42
T422
A
V
A
T
P
P
T
T
T
T
K
K
P
R
V
Site 43
S430
T
T
K
K
P
R
V
S
T
P
K
P
A
T
P
Site 44
T431
T
K
K
P
R
V
S
T
P
K
P
A
T
P
S
Site 45
T436
V
S
T
P
K
P
A
T
P
S
T
D
S
T
T
Site 46
T439
P
K
P
A
T
P
S
T
D
S
T
T
T
T
T
Site 47
S441
P
A
T
P
S
T
D
S
T
T
T
T
T
R
R
Site 48
T442
A
T
P
S
T
D
S
T
T
T
T
T
R
R
P
Site 49
T445
S
T
D
S
T
T
T
T
T
R
R
P
T
K
K
Site 50
T446
T
D
S
T
T
T
T
T
R
R
P
T
K
K
P
Site 51
T450
T
T
T
T
R
R
P
T
K
K
P
R
T
P
R
Site 52
T455
R
P
T
K
K
P
R
T
P
R
P
V
P
R
V
Site 53
T463
P
R
P
V
P
R
V
T
T
K
V
S
I
T
R
Site 54
T464
R
P
V
P
R
V
T
T
K
V
S
I
T
R
L
Site 55
T469
V
T
T
K
V
S
I
T
R
L
E
T
A
S
P
Site 56
T473
V
S
I
T
R
L
E
T
A
S
P
P
T
R
I
Site 57
S475
I
T
R
L
E
T
A
S
P
P
T
R
I
R
T
Site 58
T478
L
E
T
A
S
P
P
T
R
I
R
T
T
T
S
Site 59
T482
S
P
P
T
R
I
R
T
T
T
S
G
V
P
R
Site 60
T483
P
P
T
R
I
R
T
T
T
S
G
V
P
R
G
Site 61
T484
P
T
R
I
R
T
T
T
S
G
V
P
R
G
G
Site 62
S485
T
R
I
R
T
T
T
S
G
V
P
R
G
G
E
Site 63
T522
E
V
K
I
P
S
D
T
F
Y
D
H
E
D
T
Site 64
Y524
K
I
P
S
D
T
F
Y
D
H
E
D
T
T
T
Site 65
T529
T
F
Y
D
H
E
D
T
T
T
D
K
L
K
L
Site 66
T531
Y
D
H
E
D
T
T
T
D
K
L
K
L
T
L
Site 67
S550
Q
Q
L
V
G
E
K
S
W
V
Q
F
N
S
N
Site 68
Y562
N
S
N
S
Q
L
M
Y
G
L
P
D
S
S
H
Site 69
S567
L
M
Y
G
L
P
D
S
S
H
V
G
K
H
E
Site 70
S568
M
Y
G
L
P
D
S
S
H
V
G
K
H
E
Y
Site 71
Y575
S
H
V
G
K
H
E
Y
F
M
H
A
T
D
K
Site 72
S643
A
F
G
D
R
N
C
S
T
I
T
L
Q
N
I
Site 73
Y750
K
S
S
E
D
D
V
Y
L
H
T
V
I
P
A
Site 74
Y775
G
I
I
A
M
I
C
Y
R
K
K
R
K
G
K
Site 75
T784
K
K
R
K
G
K
L
T
L
E
D
Q
A
T
F
Site 76
T790
L
T
L
E
D
Q
A
T
F
I
K
K
G
V
P
Site 77
S807
F
A
D
E
L
D
D
S
K
P
P
P
S
S
S
Site 78
S812
D
D
S
K
P
P
P
S
S
S
M
P
L
I
L
Site 79
S813
D
S
K
P
P
P
S
S
S
M
P
L
I
L
Q
Site 80
S814
S
K
P
P
P
S
S
S
M
P
L
I
L
Q
E
Site 81
Y831
A
P
L
P
P
P
E
Y
P
N
Q
S
V
P
E
Site 82
S835
P
P
E
Y
P
N
Q
S
V
P
E
T
T
P
L
Site 83
T839
P
N
Q
S
V
P
E
T
T
P
L
N
Q
D
T
Site 84
T840
N
Q
S
V
P
E
T
T
P
L
N
Q
D
T
M
Site 85
T851
Q
D
T
M
G
E
Y
T
P
L
R
D
E
D
P
Site 86
Y863
E
D
P
N
A
P
P
Y
Q
P
P
P
P
F
T
Site 87
T870
Y
Q
P
P
P
P
F
T
A
P
M
E
G
K
G
Site 88
S878
A
P
M
E
G
K
G
S
R
P
K
N
M
T
P
Site 89
T884
G
S
R
P
K
N
M
T
P
Y
R
S
P
P
P
Site 90
Y886
R
P
K
N
M
T
P
Y
R
S
P
P
P
Y
V
Site 91
S888
K
N
M
T
P
Y
R
S
P
P
P
Y
V
P
P
Site 92
Y892
P
Y
R
S
P
P
P
Y
V
P
P
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation