PhosphoNET

           
Protein Info 
   
Short Name:  SKP2
Full Name:  S-phase kinase-associated protein 2
Alias:  Cyclin A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; FBXL1; P45skp2
Type:  Ubiquitin conjugating system
Mass (Da):  47761
Number AA:  424
UniProt ID:  Q13309
International Prot ID:  IPI00178899
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0000082  GO:0008283  GO:0019941 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S13LQEIPDLSSNVATSF
Site 2S14QEIPDLSSNVATSFT
Site 3S19LSSNVATSFTWGWDS
Site 4S26SFTWGWDSSKTSELL
Site 5S27FTWGWDSSKTSELLS
Site 6T29WGWDSSKTSELLSGM
Site 7S30GWDSSKTSELLSGMG
Site 8S48LEKEEPDSENIPQEL
Site 9S57NIPQELLSNLGHPES
Site 10S64SNLGHPESPPRKRLK
Site 11S72PPRKRLKSKGSDKDF
Site 12S75KRLKSKGSDKDFVIV
Site 13Y128SGVCKRWYRLASDES
Site 14S132KRWYRLASDESLWQT
Site 15S135YRLASDESLWQTLDL
Site 16T139SDESLWQTLDLTGKN
Site 17T143LWQTLDLTGKNLHPD
Site 18T152KNLHPDVTGRLLSQG
Site 19S179QPLAEHFSPFRVQHM
Site 20S189RVQHMDLSNSVIEVS
Site 21S191QHMDLSNSVIEVSTL
Site 22S203STLHGILSQCSKLQN
Site 23S212CSKLQNLSLEGLRLS
Site 24T225LSDPIVNTLAKNSNL
Site 25S238NLVRLNLSGCSGFSE
Site 26S256QTLLSSCSRLDELNL
Site 27T286AHVSETITQLNLSGY
Site 28S291TITQLNLSGYRKNLQ
Site 29S300YRKNLQKSDLSTLVR
Site 30S303NLQKSDLSTLVRRCP
Site 31T304LQKSDLSTLVRRCPN
Site 32S320VHLDLSDSVMLKNDC
Site 33Y336QEFFQLNYLQHLSLS
Site 34S341LNYLQHLSLSRCYDI
Site 35T400FTTIARPTIGNKKNQ
Site 36T417WGIKCRLTLQKPSCL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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