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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PTK7
Full Name:
Tyrosine-protein kinase-like 7
Alias:
Colon carcinoma kinase 4;Protein-tyrosine kinase 7
Type:
Mass (Da):
118392
Number AA:
1070
UniProt ID:
Q13308
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
G
A
A
R
G
S
P
A
R
P
R
R
L
Site 2
S39
I
V
F
I
K
Q
P
S
S
Q
D
A
L
Q
G
Site 3
S40
V
F
I
K
Q
P
S
S
Q
D
A
L
Q
G
R
Site 4
T521
M
E
F
D
K
E
A
T
V
P
C
S
A
T
G
Site 5
S525
K
E
A
T
V
P
C
S
A
T
G
R
E
K
P
Site 6
T527
A
T
V
P
C
S
A
T
G
R
E
K
P
T
I
Site 7
T779
L
G
S
G
P
A
A
T
N
K
R
H
S
T
S
Site 8
S784
A
A
T
N
K
R
H
S
T
S
D
K
M
H
F
Site 9
T785
A
T
N
K
R
H
S
T
S
D
K
M
H
F
P
Site 10
S786
T
N
K
R
H
S
T
S
D
K
M
H
F
P
R
Site 11
S794
D
K
M
H
F
P
R
S
S
L
Q
P
I
T
T
Site 12
S795
K
M
H
F
P
R
S
S
L
Q
P
I
T
T
L
Site 13
T800
R
S
S
L
Q
P
I
T
T
L
G
K
S
E
F
Site 14
T801
S
S
L
Q
P
I
T
T
L
G
K
S
E
F
G
Site 15
S831
E
T
L
V
L
V
K
S
L
Q
S
K
D
E
Q
Site 16
Y872
C
R
E
A
E
P
H
Y
M
V
L
E
Y
V
D
Site 17
Y877
P
H
Y
M
V
L
E
Y
V
D
L
G
D
L
K
Site 18
S890
L
K
Q
F
L
R
I
S
K
S
K
D
E
K
L
Site 19
S892
Q
F
L
R
I
S
K
S
K
D
E
K
L
K
S
Site 20
S899
S
K
D
E
K
L
K
S
Q
P
L
S
T
K
Q
Site 21
S903
K
L
K
S
Q
P
L
S
T
K
Q
K
V
A
L
Site 22
S939
A
A
R
N
C
L
V
S
A
Q
R
Q
V
K
V
Site 23
S947
A
Q
R
Q
V
K
V
S
A
L
G
L
S
K
D
Site 24
S952
K
V
S
A
L
G
L
S
K
D
V
Y
N
S
E
Site 25
Y956
L
G
L
S
K
D
V
Y
N
S
E
Y
Y
H
F
Site 26
Y960
K
D
V
Y
N
S
E
Y
Y
H
F
R
Q
A
W
Site 27
S984
A
I
L
E
G
D
F
S
T
K
S
D
V
W
A
Site 28
T985
I
L
E
G
D
F
S
T
K
S
D
V
W
A
F
Site 29
S987
E
G
D
F
S
T
K
S
D
V
W
A
F
G
V
Site 30
S1034
P
Q
P
E
G
C
P
S
K
L
Y
R
L
M
Q
Site 31
Y1037
E
G
C
P
S
K
L
Y
R
L
M
Q
R
C
W
Site 32
S1047
M
Q
R
C
W
A
L
S
P
K
D
R
P
S
F
Site 33
S1053
L
S
P
K
D
R
P
S
F
S
E
I
A
S
A
Site 34
S1055
P
K
D
R
P
S
F
S
E
I
A
S
A
L
G
Site 35
S1064
I
A
S
A
L
G
D
S
T
V
D
S
K
P
_
Site 36
T1065
A
S
A
L
G
D
S
T
V
D
S
K
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation