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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHAF1A
Full Name:
Chromatin assembly factor 1 subunit A
Alias:
CAF; CAF1; CAF-1; CAF-1 subunit A; CAF1A; CAF1B; CAF1P150; CAFA; CAF-I 150 kDa; CAF-Ip150; Chromatin assembly factor 1, subunit A (p150); Chromatin assembly factor I (150 kDa); Chromatin assembly factor I p150 subunit; MGC71229; P150
Type:
DNA replication
Mass (Da):
106926
Number AA:
956
UniProt ID:
Q13111
International Prot ID:
IPI00023177
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005678
GO:0005678
GO:0016585
Uniprot
OncoNet
Molecular Function:
GO:0003682
GO:0051082
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0006260
GO:0006335
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S54
K
G
K
A
D
D
M
S
D
D
Q
G
T
S
V
Site 2
T59
D
M
S
D
D
Q
G
T
S
V
Q
S
K
S
P
Site 3
S60
M
S
D
D
Q
G
T
S
V
Q
S
K
S
P
D
Site 4
S63
D
Q
G
T
S
V
Q
S
K
S
P
D
L
E
A
Site 5
S65
G
T
S
V
Q
S
K
S
P
D
L
E
A
S
L
Site 6
S71
K
S
P
D
L
E
A
S
L
D
T
L
E
N
N
Site 7
T74
D
L
E
A
S
L
D
T
L
E
N
N
C
H
V
Site 8
S83
E
N
N
C
H
V
G
S
D
I
D
F
R
P
K
Site 9
T108
F
L
R
N
R
I
E
T
S
I
G
Q
S
T
V
Site 10
T114
E
T
S
I
G
Q
S
T
V
I
I
D
L
T
E
Site 11
T120
S
T
V
I
I
D
L
T
E
D
S
N
E
Q
P
Site 12
S123
N
K
L
N
S
E
A
S
P
S
R
E
A
I
N
Site 13
S129
D
S
N
E
Q
P
D
S
L
V
D
H
N
K
L
Site 14
S138
V
D
H
N
K
L
N
S
E
A
S
P
S
R
E
Site 15
S141
N
K
L
N
S
E
A
S
P
S
R
E
A
I
N
Site 16
S143
L
N
S
E
A
S
P
S
R
E
A
I
N
G
Q
Site 17
T154
I
N
G
Q
R
E
D
T
G
D
Q
Q
G
L
L
Site 18
T175
K
L
A
F
P
G
E
T
L
S
D
I
P
C
K
Site 19
S177
A
F
P
G
E
T
L
S
D
I
P
C
K
T
E
Site 20
T183
L
S
D
I
P
C
K
T
E
E
E
G
V
G
C
Site 21
S199
G
A
G
R
R
G
D
S
Q
E
C
S
P
R
S
Site 22
S203
R
G
D
S
Q
E
C
S
P
R
S
C
P
E
L
Site 23
S206
S
Q
E
C
S
P
R
S
C
P
E
L
T
S
G
Site 24
T211
P
R
S
C
P
E
L
T
S
G
P
R
M
C
P
Site 25
S212
R
S
C
P
E
L
T
S
G
P
R
M
C
P
R
Site 26
S224
C
P
R
K
E
Q
D
S
W
S
E
A
G
G
I
Site 27
S226
R
K
E
Q
D
S
W
S
E
A
G
G
I
L
F
Site 28
S255
V
R
P
P
Q
I
K
S
L
P
A
T
P
Q
G
Site 29
T259
Q
I
K
S
L
P
A
T
P
Q
G
K
N
M
T
Site 30
T266
T
P
Q
G
K
N
M
T
P
E
S
E
V
L
E
Site 31
S269
G
K
N
M
T
P
E
S
E
V
L
E
S
F
P
Site 32
S274
P
E
S
E
V
L
E
S
F
P
E
E
D
S
V
Site 33
S280
E
S
F
P
E
E
D
S
V
L
S
H
S
S
L
Site 34
S283
P
E
E
D
S
V
L
S
H
S
S
L
S
S
P
Site 35
S285
E
D
S
V
L
S
H
S
S
L
S
S
P
S
S
Site 36
S286
D
S
V
L
S
H
S
S
L
S
S
P
S
S
T
Site 37
S288
V
L
S
H
S
S
L
S
S
P
S
S
T
S
S
Site 38
S289
L
S
H
S
S
L
S
S
P
S
S
T
S
S
P
Site 39
S291
H
S
S
L
S
S
P
S
S
T
S
S
P
E
G
Site 40
S292
S
S
L
S
S
P
S
S
T
S
S
P
E
G
P
Site 41
T293
S
L
S
S
P
S
S
T
S
S
P
E
G
P
P
Site 42
S294
L
S
S
P
S
S
T
S
S
P
E
G
P
P
A
Site 43
S295
S
S
P
S
S
T
S
S
P
E
G
P
P
A
P
Site 44
S307
P
A
P
P
K
Q
H
S
S
T
S
P
F
P
T
Site 45
S308
A
P
P
K
Q
H
S
S
T
S
P
F
P
T
S
Site 46
T309
P
P
K
Q
H
S
S
T
S
P
F
P
T
S
T
Site 47
S310
P
K
Q
H
S
S
T
S
P
F
P
T
S
T
P
Site 48
T314
S
S
T
S
P
F
P
T
S
T
P
L
R
R
I
Site 49
S315
S
T
S
P
F
P
T
S
T
P
L
R
R
I
T
Site 50
T316
T
S
P
F
P
T
S
T
P
L
R
R
I
T
K
Site 51
T322
S
T
P
L
R
R
I
T
K
K
F
V
K
G
S
Site 52
T330
K
K
F
V
K
G
S
T
E
K
N
K
L
R
L
Site 53
T454
R
F
F
Q
K
P
K
T
P
Q
A
P
K
T
L
Site 54
T460
K
T
P
Q
A
P
K
T
L
A
G
S
C
G
K
Site 55
T485
V
L
A
P
R
R
R
T
A
F
H
P
D
L
C
Site 56
S493
A
F
H
P
D
L
C
S
Q
L
D
Q
L
L
Q
Site 57
S503
D
Q
L
L
Q
Q
Q
S
G
E
F
S
F
L
K
Site 58
S507
Q
Q
Q
S
G
E
F
S
F
L
K
D
L
K
G
Site 59
S520
K
G
R
Q
P
L
R
S
G
P
T
H
V
S
T
Site 60
S526
R
S
G
P
T
H
V
S
T
R
N
A
D
I
F
Site 61
T527
S
G
P
T
H
V
S
T
R
N
A
D
I
F
N
Site 62
S535
R
N
A
D
I
F
N
S
D
V
V
I
V
E
R
Site 63
Y596
Q
D
T
K
L
L
D
Y
E
V
D
S
D
E
E
Site 64
S600
L
L
D
Y
E
V
D
S
D
E
E
W
E
E
E
Site 65
S612
E
E
E
E
P
G
E
S
L
S
H
S
E
G
D
Site 66
S614
E
E
P
G
E
S
L
S
H
S
E
G
D
D
D
Site 67
S616
P
G
E
S
L
S
H
S
E
G
D
D
D
D
D
Site 68
Y640
G
F
F
V
P
H
G
Y
L
S
E
D
E
G
V
Site 69
S642
F
V
P
H
G
Y
L
S
E
D
E
G
V
T
E
Site 70
T722
L
P
A
Q
E
E
Q
T
P
K
A
S
K
R
E
Site 71
S726
E
E
Q
T
P
K
A
S
K
R
E
R
R
D
E
Site 72
S767
H
C
R
R
G
L
L
S
N
H
T
G
S
P
R
Site 73
T770
R
G
L
L
S
N
H
T
G
S
P
R
S
P
S
Site 74
S772
L
L
S
N
H
T
G
S
P
R
S
P
S
T
T
Site 75
S775
N
H
T
G
S
P
R
S
P
S
T
T
Y
L
H
Site 76
S777
T
G
S
P
R
S
P
S
T
T
Y
L
H
T
P
Site 77
T778
G
S
P
R
S
P
S
T
T
Y
L
H
T
P
T
Site 78
T779
S
P
R
S
P
S
T
T
Y
L
H
T
P
T
P
Site 79
Y780
P
R
S
P
S
T
T
Y
L
H
T
P
T
P
S
Site 80
T783
P
S
T
T
Y
L
H
T
P
T
P
S
E
D
A
Site 81
T785
T
T
Y
L
H
T
P
T
P
S
E
D
A
A
I
Site 82
S787
Y
L
H
T
P
T
P
S
E
D
A
A
I
P
S
Site 83
S794
S
E
D
A
A
I
P
S
K
S
R
L
K
R
L
Site 84
S796
D
A
A
I
P
S
K
S
R
L
K
R
L
I
S
Site 85
S803
S
R
L
K
R
L
I
S
E
N
S
V
Y
E
K
Site 86
S806
K
R
L
I
S
E
N
S
V
Y
E
K
R
P
D
Site 87
Y808
L
I
S
E
N
S
V
Y
E
K
R
P
D
F
R
Site 88
S827
V
H
P
Q
V
L
Q
S
F
Q
Q
E
H
L
P
Site 89
T843
P
C
Q
W
S
Y
V
T
S
V
P
S
A
P
K
Site 90
S844
C
Q
W
S
Y
V
T
S
V
P
S
A
P
K
E
Site 91
S847
S
Y
V
T
S
V
P
S
A
P
K
E
D
S
G
Site 92
S853
P
S
A
P
K
E
D
S
G
S
V
P
S
T
G
Site 93
S855
P
I
S
L
K
R
K
S
A
G
S
M
C
I
T
Site 94
S858
E
D
S
G
S
V
P
S
T
G
P
S
Q
G
T
Site 95
T859
D
S
G
S
V
P
S
T
G
P
S
Q
G
T
P
Site 96
S862
S
V
P
S
T
G
P
S
Q
G
T
P
I
S
L
Site 97
T865
S
T
G
P
S
Q
G
T
P
I
S
L
K
R
K
Site 98
S868
P
S
Q
G
T
P
I
S
L
K
R
K
S
A
G
Site 99
S873
P
I
S
L
K
R
K
S
A
G
S
M
C
I
T
Site 100
S876
L
K
R
K
S
A
G
S
M
C
I
T
Q
F
M
Site 101
T880
S
A
G
S
M
C
I
T
Q
F
M
K
K
R
R
Site 102
S933
G
K
A
T
L
T
A
S
P
L
G
A
S
_
_
Site 103
T947
G
V
D
T
G
K
A
T
L
T
S
S
P
L
G
Site 104
S950
T
G
K
A
T
L
T
S
S
P
L
G
A
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation