PhosphoNET

           
Protein Info 
   
Short Name:  FOXC1
Full Name:  Forkhead box protein C1
Alias:  ARA; FKHL7; Forkhead box C1; Forkhead-related protein FKHL7; FREAC3; FREAC-3; IGDA; IHG1; IRID1; Iridogoniodysgenesis type 1; Myeloid factor-delta
Type:  Transcription factor; Cell development/differentiation; Cell cycle regulation
Mass (Da):  56789
Number AA:  553
UniProt ID:  Q12948
International Prot ID:  IPI00290377
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005720  GO:0000790  GO:0000792 Uniprot OncoNet
Molecular Function:  GO:0008301  GO:0043565  GO:0016563 PhosphoSite+ KinaseNET
Biological Process:  GO:0045930  GO:0042475  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MQARYSVSSPNSL
Site 2S8MQARYSVSSPNSLGV
Site 3S9QARYSVSSPNSLGVV
Site 4S12YSVSSPNSLGVVPYL
Site 5Y18NSLGVVPYLGGEQSY
Site 6S24PYLGGEQSYYRAAAA
Site 7Y26LGGEQSYYRAAAAAA
Site 8S45TAMPAPMSVYSHPAH
Site 9Y47MPAPMSVYSHPAHAE
Site 10Y64PGGMARAYGPYTPQP
Site 11Y67MARAYGPYTPQPQPK
Site 12T68ARAYGPYTPQPQPKD
Site 13Y115IMDRFPFYRDNKQGW
Site 14S131NSIRHNLSLNECFVK
Site 15T153PGKGSYWTLDPDSYN
Site 16Y159WTLDPDSYNMFENGS
Site 17S166YNMFENGSFLRRRRR
Site 18T228VRIQDIKTENGTCPS
Site 19T232DIKTENGTCPSPPQP
Site 20S235TENGTCPSPPQPLSP
Site 21S241PSPPQPLSPAAALGS
Site 22S248SPAAALGSGSAAAVP
Site 23S259AAVPKIESPDSSSSS
Site 24S262PKIESPDSSSSSLSS
Site 25S263KIESPDSSSSSLSSG
Site 26S264IESPDSSSSSLSSGS
Site 27S265ESPDSSSSSLSSGSS
Site 28S266SPDSSSSSLSSGSSP
Site 29S268DSSSSSLSSGSSPPG
Site 30S269SSSSSLSSGSSPPGS
Site 31S271SSSLSSGSSPPGSLP
Site 32S272SSLSSGSSPPGSLPS
Site 33S276SGSSPPGSLPSARPL
Site 34S279SPPGSLPSARPLSLD
Site 35S284LPSARPLSLDGADSA
Site 36S290LSLDGADSAPPPPAP
Site 37S298APPPPAPSAPPPHHS
Site 38S305SAPPPHHSQGFSVDN
Site 39S309PHHSQGFSVDNIMTS
Site 40S316SVDNIMTSLRGSPQS
Site 41S320IMTSLRGSPQSAAAE
Site 42S323SLRGSPQSAAAELSS
Site 43S329QSAAAELSSGLLASA
Site 44S340LASAAASSRAGIAPP
Site 45Y353PPLALGAYSPGQSSL
Site 46S354PLALGAYSPGQSSLY
Site 47S358GAYSPGQSSLYSSPC
Site 48S359AYSPGQSSLYSSPCS
Site 49Y361SPGQSSLYSSPCSQT
Site 50S362PGQSSLYSSPCSQTS
Site 51S363GQSSLYSSPCSQTSS
Site 52S366SLYSSPCSQTSSAGS
Site 53T368YSSPCSQTSSAGSSG
Site 54S369SSPCSQTSSAGSSGG
Site 55S370SPCSQTSSAGSSGGG
Site 56S373SQTSSAGSSGGGGGG
Site 57S374QTSSAGSSGGGGGGA
Site 58Y393GAGGAGTYHCNLQAM
Site 59Y403NLQAMSLYAAGERGG
Site 60S422APGGAGGSAVDDPLP
Site 61Y431VDDPLPDYSLPPVTS
Site 62S432DDPLPDYSLPPVTSS
Site 63T437DYSLPPVTSSSSSSL
Site 64S438YSLPPVTSSSSSSLS
Site 65S439SLPPVTSSSSSSLSH
Site 66S440LPPVTSSSSSSLSHG
Site 67S441PPVTSSSSSSLSHGG
Site 68S442PVTSSSSSSLSHGGG
Site 69S443VTSSSSSSLSHGGGG
Site 70S445SSSSSSLSHGGGGGG
Site 71T471AAHQGRLTSWYLNQA
Site 72S472AHQGRLTSWYLNQAG
Site 73Y474QGRLTSWYLNQAGGD
Site 74Y497AAAAAAGYPGQQQNF
Site 75S506GQQQNFHSVREMFES
Site 76S513SVREMFESQRIGLNN
Site 77S521QRIGLNNSPVNGNSS
Site 78S535SCQMAFPSSQSLYRT
Site 79S536CQMAFPSSQSLYRTS
Site 80S538MAFPSSQSLYRTSGA
Site 81Y540FPSSQSLYRTSGAFV
Site 82T542SSQSLYRTSGAFVYD
Site 83S543SQSLYRTSGAFVYDC
Site 84Y548RTSGAFVYDCSKF__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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