PhosphoNET

           
Protein Info 
   
Short Name:  KCNMA1
Full Name:  Calcium-activated potassium channel subunit alpha-1
Alias:  BK channel; BKCA alpha; Calcium-activated potassium channel, subfamily M subunit alpha-1; Calcium-activated potassium channel, subfamily M, alpha subunit 1; HSlo; K(VCA)alpha; KCa1.1; KCMA1; Maxi K channel; MaxiK; MSLO1; Potassium large conductance calcium-activated channel, subfamily M, alpha member 1; Slo; Slo1; Slo-alpha; Slowpoke; Slowpoke homolog
Type:  Endoplasmic reticulum; Channel, potassium; Membrane protein, integral
Mass (Da):  137560
Number AA:  1236
UniProt ID:  Q12791
International Prot ID:  IPI00164387
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016324  GO:0005901  GO:0009897 Uniprot OncoNet
Molecular Function:  GO:0003779  GO:0005509  GO:0015269 PhosphoSite+ KinaseNET
Biological Process:  GO:0007628  GO:0042491  GO:0048469 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11GGGGGGGSSGGGGGG
Site 2S12GGGGGGSSGGGGGGG
Site 3S21GGGGGGGSSLRMSSN
Site 4S22GGGGGGSSLRMSSNI
Site 5S26GGSSLRMSSNIHANH
Site 6S27GSSLRMSSNIHANHL
Site 7S35NIHANHLSLDASSSS
Site 8S39NHLSLDASSSSSSSS
Site 9S40HLSLDASSSSSSSSS
Site 10S41LSLDASSSSSSSSSS
Site 11S42SLDASSSSSSSSSSS
Site 12S43LDASSSSSSSSSSSS
Site 13S44DASSSSSSSSSSSSS
Site 14S45ASSSSSSSSSSSSSS
Site 15S46SSSSSSSSSSSSSSS
Site 16S54SSSSSSSSSSSSSSV
Site 17S55SSSSSSSSSSSSSVH
Site 18S56SSSSSSSSSSSSVHE
Site 19S57SSSSSSSSSSSVHEP
Site 20S58SSSSSSSSSSVHEPK
Site 21S59SSSSSSSSSVHEPKM
Site 22S60SSSSSSSSVHEPKMD
Site 23S136QKINNGSSQADGTLK
Site 24T141GSSQADGTLKPVDEK
Site 25Y359TVGYGDVYAKTTLGR
Site 26Y397LIGNRKKYGGSYSAV
Site 27S400NRKKYGGSYSAVSGR
Site 28Y401RKKYGGSYSAVSGRK
Site 29S402KKYGGSYSAVSGRKH
Site 30S405GGSYSAVSGRKHIVV
Site 31S420CGHITLESVSNFLKD
Site 32T461ALFKRHFTQVEFYQG
Site 33Y515RVISIKNYHPKIRII
Site 34T523HPKIRIITQMLQYHN
Site 35S562KLGFIAQSCLAQGLS
Site 36S569SCLAQGLSTMLANLF
Site 37S580ANLFSMRSFIKIEED
Site 38Y592EEDTWQKYYLEGVSN
Site 39Y593EDTWQKYYLEGVSNE
Site 40Y602EGVSNEMYTEYLSSA
Site 41T603GVSNEMYTEYLSSAF
Site 42Y605SNEMYTEYLSSAFVG
Site 43S637MIAIEYKSANRESRI
Site 44S642YKSANRESRILINPG
Site 45S665TLGFFIASDAKEVKR
Site 46T685KACHDDITDPKRIKK
Site 47Y703KRPKMSIYKRMRRAC
Site 48S722GRSERDCSCMSGRVR
Site 49S725ERDCSCMSGRVRGNV
Site 50T734RVRGNVDTLERAFPL
Site 51S743ERAFPLSSVSVNDCS
Site 52S750SVSVNDCSTSFRAFE
Site 53S752SVNDCSTSFRAFEDE
Site 54T763FEDEQPSTLSPKKKQ
Site 55S765DEQPSTLSPKKKQRN
Site 56S778RNGGMRNSPNTSPKL
Site 57T781GMRNSPNTSPKLMRH
Site 58S782MRNSPNTSPKLMRHD
Site 59S804DQIDNMDSNVKKYDS
Site 60Y809MDSNVKKYDSTGMFH
Site 61Y871LRASNFHYHELKHIV
Site 62Y885VFVGSIEYLKREWET
Site 63T936NQNNIDDTSLQDKEC
Site 64S947DKECILASLNIKSMQ
Site 65S958KSMQFDDSIGVLQAN
Site 66S966IGVLQANSQGFTPPG
Site 67T970QANSQGFTPPGMDRS
Site 68S977TPPGMDRSSPDNSPV
Site 69S978PPGMDRSSPDNSPVH
Site 70S982DRSSPDNSPVHGMLR
Site 71S992HGMLRQPSITTGVNI
Site 72T1024DDDDDPDTELYLTQP
Site 73Y1027DDPDTELYLTQPFAC
Site 74T1029PDTELYLTQPFACGT
Site 75S1048SVLDSLMSATYFNDN
Site 76Y1051DSLMSATYFNDNILT
Site 77Y1086ENALRGGYSTPQTLA
Site 78S1087NALRGGYSTPQTLAN
Site 79T1088ALRGGYSTPQTLANR
Site 80T1091GGYSTPQTLANRDRC
Site 81Y1119DLGDGGCYGDLFCKA
Site 82S1146RLRDAHLSTPSQCTK
Site 83T1147LRDAHLSTPSQCTKR
Site 84S1149DAHLSTPSQCTKRYV
Site 85T1152LSTPSQCTKRYVITN
Site 86Y1155PSQCTKRYVITNPPY
Site 87Y1162YVITNPPYEFELVPT
Site 88S1185FDHNAGQSRASLSHS
Site 89S1188NAGQSRASLSHSSHS
Site 90S1190GQSRASLSHSSHSSQ
Site 91S1192SRASLSHSSHSSQSS
Site 92S1193RASLSHSSHSSQSSS
Site 93S1195SLSHSSHSSQSSSKK
Site 94S1196LSHSSHSSQSSSKKS
Site 95S1198HSSHSSQSSSKKSSS
Site 96S1199SSHSSQSSSKKSSSV
Site 97S1200SHSSQSSSKKSSSVH
Site 98S1203SQSSSKKSSSVHSIP
Site 99S1204QSSSKKSSSVHSIPS
Site 100S1205SSSKKSSSVHSIPST
Site 101S1208KKSSSVHSIPSTANR
Site 102S1211SSVHSIPSTANRQNR
Site 103T1212SVHSIPSTANRQNRP
Site 104S1221NRQNRPKSRESRDKQ
Site 105S1224NRPKSRESRDKQKYV
Site 106Y1230ESRDKQKYVQEERL_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation