PhosphoNET

           
Protein Info 
   
Short Name:  dematin
Full Name:  Dematin
Alias:  DEMA; DMT; EPB49; Erythrocyte membrane protein band 4.9; Erythrocyte membrane protein band 4.9 (dematin)
Type:  Actin binding protein
Mass (Da):  45514
Number AA:  405
UniProt ID:  Q08495
International Prot ID:  IPI00292290
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0015629  GO:0005737   Uniprot OncoNet
Molecular Function:  GO:0003779     PhosphoSite+ KinaseNET
Biological Process:  GO:0051017  GO:0051693   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T10RLQKQPLTSPGSVSP
Site 2S11LQKQPLTSPGSVSPS
Site 3S14QPLTSPGSVSPSRDS
Site 4S16LTSPGSVSPSRDSSV
Site 5S18SPGSVSPSRDSSVPG
Site 6S21SVSPSRDSSVPGSPS
Site 7S22VSPSRDSSVPGSPSS
Site 8S26RDSSVPGSPSSIVAK
Site 9S28SSVPGSPSSIVAKMD
Site 10S29SVPGSPSSIVAKMDN
Site 11Y41MDNQVLGYKDLAAIP
Site 12Y64ERPDLMIYEPHFTYS
Site 13T69MIYEPHFTYSLLEHV
Site 14Y70IYEPHFTYSLLEHVE
Site 15S71YEPHFTYSLLEHVEL
Site 16S81EHVELPRSRERSLSP
Site 17S85LPRSRERSLSPKSTS
Site 18S87RSRERSLSPKSTSPP
Site 19S90ERSLSPKSTSPPPSP
Site 20T91RSLSPKSTSPPPSPE
Site 21S92SLSPKSTSPPPSPEV
Site 22S96KSTSPPPSPEVWADS
Site 23S103SPEVWADSRSPGIIS
Site 24S105EVWADSRSPGIISQA
Site 25S110SRSPGIISQASAPRT
Site 26S113PGIISQASAPRTTGT
Site 27T117SQASAPRTTGTPRTS
Site 28T118QASAPRTTGTPRTSL
Site 29T120SAPRTTGTPRTSLPH
Site 30T123RTTGTPRTSLPHFHH
Site 31S124TTGTPRTSLPHFHHP
Site 32T133PHFHHPETSRPDSNI
Site 33S138PETSRPDSNIYKKPP
Site 34Y141SRPDSNIYKKPPIYK
Site 35Y147IYKKPPIYKQRESVG
Site 36S152PIYKQRESVGGSPQT
Site 37S156QRESVGGSPQTKHLI
Site 38S171EDLIIESSKFPAAQP
Site 39Y191PAKIETDYWPCPPSL
Site 40S197DYWPCPPSLAVVETE
Site 41S211EWRKRKASRRGAEEE
Site 42S226EEEEDDDSGEEMKAL
Site 43S242ERQREELSKVTSNLG
Site 44S246EELSKVTSNLGKMIL
Site 45S260LKEEMEKSLPIRRKT
Site 46T267SLPIRRKTRSLPDRT
Site 47S269PIRRKTRSLPDRTPF
Site 48T274TRSLPDRTPFHTSLH
Site 49T278PDRTPFHTSLHQGTS
Site 50S279DRTPFHTSLHQGTSK
Site 51T284HTSLHQGTSKSSSLP
Site 52S285TSLHQGTSKSSSLPA
Site 53S287LHQGTSKSSSLPAYG
Site 54S288HQGTSKSSSLPAYGR
Site 55S289QGTSKSSSLPAYGRT
Site 56Y293KSSSLPAYGRTTLSR
Site 57T297LPAYGRTTLSRLQST
Site 58S299AYGRTTLSRLQSTEF
Site 59S303TTLSRLQSTEFSPSG
Site 60T304TLSRLQSTEFSPSGS
Site 61S307RLQSTEFSPSGSETG
Site 62S309QSTEFSPSGSETGSP
Site 63S311TEFSPSGSETGSPGL
Site 64T313FSPSGSETGSPGLQN
Site 65S315PSGSETGSPGLQNGE
Site 66S333GRMDRGNSLPCVLEQ
Site 67Y343CVLEQKIYPYEMLVV
Site 68S372MRLERHLSAEDFSRV
Site 69S383FSRVFAMSPEEFGKL
Site 70S403NELKKKASLF_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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