PhosphoNET

           
Protein Info 
   
Short Name:  CACNB2
Full Name:  Voltage-dependent L-type calcium channel subunit beta-2
Alias:  CACB2; CACNLB2; Calcium channel voltage-dependent subunit beta 2; Calcium channel, voltage-dependent, beta 2 subunit; CCB2; Dihydropyridine-sensitive L-type, calcium channel beta-2; Lambert- Eaton myasthenic syndrome antigen B; Lambert-Eaton myasthenic syndrome antigen B; MYSB; Voltage-dependent calcium channel beta-2 subunit; VSCC, L type, beta 2a isoform; VSCC, L type, beta 2d isoform; VSCC, L type, beta2
Type:  Channel, calcium
Mass (Da):  73581
Number AA:  660
UniProt ID:  Q08289
International Prot ID:  IPI00218399
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887  GO:0005891   Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0005515  GO:0005245 PhosphoSite+ KinaseNET
Biological Process:  GO:0006816  GO:0007528   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MVQRDMSKSPPTAA
Site 2S9VQRDMSKSPPTAAAA
Site 3S55RKNRFKGSDGSTSSD
Site 4S58RFKGSDGSTSSDTTS
Site 5T59FKGSDGSTSSDTTSN
Site 6S60KGSDGSTSSDTTSNS
Site 7S61GSDGSTSSDTTSNSF
Site 8T63DGSTSSDTTSNSFVR
Site 9T64GSTSSDTTSNSFVRQ
Site 10S65STSSDTTSNSFVRQG
Site 11S67SSDTTSNSFVRQGSA
Site 12S73NSFVRQGSADSYTSR
Site 13S76VRQGSADSYTSRPSD
Site 14Y77RQGSADSYTSRPSDS
Site 15T78QGSADSYTSRPSDSD
Site 16S79GSADSYTSRPSDSDV
Site 17S82DSYTSRPSDSDVSLE
Site 18S84YTSRPSDSDVSLEED
Site 19S87RPSDSDVSLEEDREA
Site 20Y125AVRTNVSYSAAHEDD
Site 21S175CEIGFIPSPVKLENM
Site 22Y196RAKQGKFYSSKSGGN
Site 23S197AKQGKFYSSKSGGNS
Site 24S198KQGKFYSSKSGGNSS
Site 25S200GKFYSSKSGGNSSSS
Site 26S204SSKSGGNSSSSLGDI
Site 27S205SKSGGNSSSSLGDIV
Site 28S206KSGGNSSSSLGDIVP
Site 29S207SGGNSSSSLGDIVPS
Site 30S214SLGDIVPSSRKSTPP
Site 31S215LGDIVPSSRKSTPPS
Site 32S218IVPSSRKSTPPSSAI
Site 33T219VPSSRKSTPPSSAID
Site 34S222SRKSTPPSSAIDIDA
Site 35S223RKSTPPSSAIDIDAT
Site 36T230SAIDIDATGLDAEEN
Site 37S245DIPANHRSPKPSANS
Site 38S249NHRSPKPSANSVTSP
Site 39S252SPKPSANSVTSPHSK
Site 40S255PSANSVTSPHSKEKR
Site 41S258NSVTSPHSKEKRMPF
Site 42T269RMPFFKKTEHTPPYD
Site 43T272FFKKTEHTPPYDVVP
Site 44Y275KTEHTPPYDVVPSMR
Site 45Y294VGPSLKGYEVTDMMQ
Site 46S317HRFEGRISITRVTAD
Site 47S331DISLAKRSVLNNPSK
Site 48S345KHAIIERSNTRSSLA
Site 49T347AIIERSNTRSSLAEV
Site 50S349IERSNTRSSLAEVQS
Site 51S350ERSNTRSSLAEVQSE
Site 52S356SSLAEVQSEIERIFE
Site 53S385INHPAQLSKTSLAPI
Site 54S400IVYVKISSPKVLQRL
Site 55S410VLQRLIKSRGKSQAK
Site 56S414LIKSRGKSQAKHLNV
Site 57Y456ACEHLADYLEAYWKA
Site 58T464LEAYWKATHPPSSSL
Site 59S468WKATHPPSSSLPNPL
Site 60S469KATHPPSSSLPNPLL
Site 61S470ATHPPSSSLPNPLLS
Site 62S477SLPNPLLSRTLATSS
Site 63T479PNPLLSRTLATSSLP
Site 64T482LLSRTLATSSLPLSP
Site 65S484SRTLATSSLPLSPTL
Site 66S488ATSSLPLSPTLASNS
Site 67T490SSLPLSPTLASNSQG
Site 68S493PLSPTLASNSQGSQG
Site 69S495SPTLASNSQGSQGDQ
Site 70T504GSQGDQRTDRSAPIR
Site 71S507GDQRTDRSAPIRSAS
Site 72S514SAPIRSASQAEEEPS
Site 73S521SQAEEEPSVEPVKKS
Site 74S528SVEPVKKSQHRSSSS
Site 75S532VKKSQHRSSSSAPHH
Site 76S533KKSQHRSSSSAPHHN
Site 77S534KSQHRSSSSAPHHNH
Site 78S535SQHRSSSSAPHHNHR
Site 79S543APHHNHRSGTSRGLS
Site 80T545HHNHRSGTSRGLSRQ
Site 81S550SGTSRGLSRQETFDS
Site 82T554RGLSRQETFDSETQE
Site 83S557SRQETFDSETQESRD
Site 84T559QETFDSETQESRDSA
Site 85S565ETQESRDSAYVEPKE
Site 86Y567QESRDSAYVEPKEDY
Site 87Y574YVEPKEDYSHDHVDH
Site 88Y582SHDHVDHYASHRDHN
Site 89T594DHNHRDETHGSSDHR
Site 90S597HRDETHGSSDHRHRE
Site 91S598RDETHGSSDHRHRES
Site 92S605SDHRHRESRHRSRDV
Site 93S609HRESRHRSRDVDREQ
Site 94S630KQRSRHKSKDRYCEK
Site 95Y634RHKSKDRYCEKDGEV
Site 96S643EKDGEVISKKRNEAG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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