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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPARA
Full Name:
Peroxisome proliferator-activated receptor alpha
Alias:
HPPAR; NR1C1; PPAR; PPARA Peroxisome proliferator-activated receptor alpha; PPAR-alpha
Type:
Receptor, nuclear
Mass (Da):
52225
Number AA:
468
UniProt ID:
Q07869
International Prot ID:
IPI00020097
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008144
GO:0008289
GO:0003707
PhosphoSite+
KinaseNET
Biological Process:
GO:0006631
GO:0015908
GO:0032099
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
V
D
T
E
S
P
L
C
P
L
S
P
Site 2
S12
E
S
P
L
C
P
L
S
P
L
E
A
G
D
L
Site 3
S21
L
E
A
G
D
L
E
S
P
L
S
E
E
F
L
Site 4
S24
G
D
L
E
S
P
L
S
E
E
F
L
Q
E
M
Site 5
S38
M
G
N
I
Q
E
I
S
Q
S
I
G
E
D
S
Site 6
S40
N
I
Q
E
I
S
Q
S
I
G
E
D
S
S
G
Site 7
S45
S
Q
S
I
G
E
D
S
S
G
S
F
G
F
T
Site 8
S46
Q
S
I
G
E
D
S
S
G
S
F
G
F
T
E
Site 9
S48
I
G
E
D
S
S
G
S
F
G
F
T
E
Y
Q
Site 10
T52
S
S
G
S
F
G
F
T
E
Y
Q
Y
L
G
S
Site 11
Y54
G
S
F
G
F
T
E
Y
Q
Y
L
G
S
C
P
Site 12
Y56
F
G
F
T
E
Y
Q
Y
L
G
S
C
P
G
S
Site 13
S59
T
E
Y
Q
Y
L
G
S
C
P
G
S
D
G
S
Site 14
S63
Y
L
G
S
C
P
G
S
D
G
S
V
I
T
D
Site 15
S66
S
C
P
G
S
D
G
S
V
I
T
D
T
L
S
Site 16
T69
G
S
D
G
S
V
I
T
D
T
L
S
P
A
S
Site 17
T71
D
G
S
V
I
T
D
T
L
S
P
A
S
S
P
Site 18
S73
S
V
I
T
D
T
L
S
P
A
S
S
P
S
S
Site 19
S76
T
D
T
L
S
P
A
S
S
P
S
S
V
T
Y
Site 20
S77
D
T
L
S
P
A
S
S
P
S
S
V
T
Y
P
Site 21
S80
S
P
A
S
S
P
S
S
V
T
Y
P
V
V
P
Site 22
T82
A
S
S
P
S
S
V
T
Y
P
V
V
P
G
S
Site 23
S89
T
Y
P
V
V
P
G
S
V
D
E
S
P
S
G
Site 24
S93
V
P
G
S
V
D
E
S
P
S
G
A
L
N
I
Site 25
S95
G
S
V
D
E
S
P
S
G
A
L
N
I
E
C
Site 26
S110
R
I
C
G
D
K
A
S
G
Y
H
Y
G
V
H
Site 27
Y112
C
G
D
K
A
S
G
Y
H
Y
G
V
H
A
C
Site 28
Y114
D
K
A
S
G
Y
H
Y
G
V
H
A
C
E
G
Site 29
T129
C
K
G
F
F
R
R
T
I
R
L
K
L
V
Y
Site 30
Y136
T
I
R
L
K
L
V
Y
D
K
C
D
R
S
C
Site 31
S142
V
Y
D
K
C
D
R
S
C
K
I
Q
K
K
N
Site 32
S179
R
F
G
R
M
P
R
S
E
K
A
K
L
K
A
Site 33
S198
C
E
H
D
I
E
D
S
E
T
A
D
L
K
S
Site 34
T200
H
D
I
E
D
S
E
T
A
D
L
K
S
L
A
Site 35
S205
S
E
T
A
D
L
K
S
L
A
K
R
I
Y
E
Site 36
Y211
K
S
L
A
K
R
I
Y
E
A
Y
L
K
N
F
Site 37
Y214
A
K
R
I
Y
E
A
Y
L
K
N
F
N
M
N
Site 38
S230
V
K
A
R
V
I
L
S
G
K
A
S
N
N
P
Site 39
Y334
K
D
G
M
L
V
A
Y
G
N
G
F
I
T
R
Site 40
S346
I
T
R
E
F
L
K
S
L
R
K
P
F
C
D
Site 41
S414
V
L
R
L
H
L
Q
S
N
H
P
D
D
I
F
Site 42
S452
Q
I
I
K
K
T
E
S
D
A
A
L
H
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation