PhosphoNET

           
Protein Info 
   
Short Name:  BAX
Full Name:  Apoptosis regulator BAX
Alias:  Apoptosis regulator BAX, membrane isoform alpha; BAXA; Bcl2-associated X protein; BCL2L4
Type:  Apoptosis protein, Bcl family
Mass (Da):  21184
Number AA:  192
UniProt ID:  Q07812
International Prot ID:  IPI00443773
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005789  GO:0005741 Uniprot OncoNet
Molecular Function:  GO:0051434  GO:0008289  GO:0046982 PhosphoSite+ KinaseNET
Biological Process:  GO:0001783  GO:0006309  GO:0008635 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T14QPRGGGPTSSEQIMK
Site 2S15PRGGGPTSSEQIMKT
Site 3S16RGGGPTSSEQIMKTG
Site 4T22SSEQIMKTGALLLQG
Site 5S55DPVPQDASTKKLSEC
Site 6T56PVPQDASTKKLSECL
Site 7S60DASTKKLSECLKRIG
Site 8S72RIGDELDSNMELQRM
Site 9T85RMIAAVDTDSPREVF
Site 10S87IAAVDTDSPREVFFR
Site 11T135KVPELIRTIMGWTLD
Site 12T140IRTIMGWTLDFLRER
Site 13S163GGWDGLLSYFGTPTW
Site 14Y164GWDGLLSYFGTPTWQ
Site 15T167GLLSYFGTPTWQTVT
Site 16S184VAGVLTASLTIWKKM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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