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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC18A2
Full Name:
Synaptic vesicular amine transporter
Alias:
Monoamine transporter; Synaptic vesicular amine transporter; VAT2; Vesicular amine transporter 2; VMAT2
Type:
Transporter
Mass (Da):
55713
Number AA:
514
UniProt ID:
Q05940
International Prot ID:
IPI00016759
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031410
GO:0005887
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0008504
PhosphoSite+
KinaseNET
Biological Process:
GO:0015844
GO:0006836
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
L
V
R
W
L
Q
E
S
R
R
S
R
K
L
I
Site 2
S18
W
L
Q
E
S
R
R
S
R
K
L
I
L
F
I
Site 3
Y49
P
I
I
P
S
Y
L
Y
S
I
K
H
E
K
N
Site 4
S50
I
I
P
S
Y
L
Y
S
I
K
H
E
K
N
A
Site 5
T68
Q
T
A
R
P
V
H
T
A
S
I
S
D
S
F
Site 6
S70
A
R
P
V
H
T
A
S
I
S
D
S
F
Q
S
Site 7
S74
H
T
A
S
I
S
D
S
F
Q
S
I
F
S
Y
Site 8
S77
S
I
S
D
S
F
Q
S
I
F
S
Y
Y
D
N
Site 9
Y81
S
F
Q
S
I
F
S
Y
Y
D
N
S
T
M
V
Site 10
Y82
F
Q
S
I
F
S
Y
Y
D
N
S
T
M
V
T
Site 11
T86
F
S
Y
Y
D
N
S
T
M
V
T
G
N
A
T
Site 12
T97
G
N
A
T
R
D
L
T
L
H
Q
T
A
T
Q
Site 13
T103
L
T
L
H
Q
T
A
T
Q
H
M
V
T
N
A
Site 14
S111
Q
H
M
V
T
N
A
S
A
V
P
S
D
C
P
Site 15
S115
T
N
A
S
A
V
P
S
D
C
P
S
E
D
K
Site 16
S119
A
V
P
S
D
C
P
S
E
D
K
D
L
L
N
Site 17
S196
R
S
L
Q
G
I
G
S
S
C
S
S
V
A
G
Site 18
S209
A
G
M
G
M
L
A
S
V
Y
T
D
D
E
E
Site 19
Y211
M
G
M
L
A
S
V
Y
T
D
D
E
E
R
G
Site 20
S240
L
V
G
P
P
F
G
S
V
L
Y
E
F
V
G
Site 21
S279
P
S
R
V
Q
P
E
S
Q
K
G
T
P
L
T
Site 22
T283
Q
P
E
S
Q
K
G
T
P
L
T
T
L
L
K
Site 23
T286
S
Q
K
G
T
P
L
T
T
L
L
K
D
P
Y
Site 24
S472
P
L
C
F
F
L
R
S
P
P
A
K
E
E
K
Site 25
T496
P
I
K
T
K
M
Y
T
Q
N
N
I
Q
S
Y
Site 26
Y503
T
Q
N
N
I
Q
S
Y
P
I
G
E
D
E
E
Site 27
S511
P
I
G
E
D
E
E
S
E
S
D
_
_
_
_
Site 28
S513
G
E
D
E
E
S
E
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation