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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CALD1
Full Name:
Caldesmon
Alias:
CDM; DKFZp779D0769; Putative uncharacterized protein DKFZp779D0769
Type:
Cytoskeletal, calcium binding protein
Mass (Da):
93250
Number AA:
793
UniProt ID:
Q05682
International Prot ID:
IPI00014516
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
GO:0043226
GO:0043228
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005516
GO:0017022
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
GO:0006936
GO:0006928
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
L
E
A
E
R
I
A
Y
Q
R
N
D
D
D
E
Site 2
S73
V
E
V
N
A
Q
N
S
V
P
D
E
E
A
K
Site 3
T81
V
P
D
E
E
A
K
T
T
T
T
N
T
Q
V
Site 4
T82
P
D
E
E
A
K
T
T
T
T
N
T
Q
V
E
Site 5
T83
D
E
E
A
K
T
T
T
T
N
T
Q
V
E
G
Site 6
T84
E
E
A
K
T
T
T
T
N
T
Q
V
E
G
D
Site 7
T86
A
K
T
T
T
T
N
T
Q
V
E
G
D
D
E
Site 8
T124
R
Q
K
E
F
D
P
T
I
T
D
A
S
L
S
Site 9
S129
D
P
T
I
T
D
A
S
L
S
L
P
S
R
R
Site 10
S131
T
I
T
D
A
S
L
S
L
P
S
R
R
M
Q
Site 11
T141
S
R
R
M
Q
N
D
T
A
E
N
E
T
T
E
Site 12
T147
D
T
A
E
N
E
T
T
E
K
E
E
K
S
E
Site 13
S153
T
T
E
K
E
E
K
S
E
S
R
Q
E
R
Y
Site 14
S155
E
K
E
E
K
S
E
S
R
Q
E
R
Y
E
I
Site 15
Y160
S
E
S
R
Q
E
R
Y
E
I
E
E
T
E
T
Site 16
T165
E
R
Y
E
I
E
E
T
E
T
V
T
K
S
Y
Site 17
T167
Y
E
I
E
E
T
E
T
V
T
K
S
Y
Q
K
Site 18
S171
E
T
E
T
V
T
K
S
Y
Q
K
N
D
W
R
Site 19
Y172
T
E
T
V
T
K
S
Y
Q
K
N
D
W
R
D
Site 20
S202
E
E
K
P
K
R
G
S
I
G
E
N
Q
V
E
Site 21
T217
V
M
V
E
E
K
T
T
E
S
Q
E
E
T
V
Site 22
T223
T
T
E
S
Q
E
E
T
V
V
M
S
L
K
N
Site 23
S235
L
K
N
G
Q
I
S
S
E
E
P
K
Q
E
E
Site 24
S248
E
E
E
R
E
Q
G
S
D
E
I
S
H
H
E
Site 25
S252
E
Q
G
S
D
E
I
S
H
H
E
K
M
E
E
Site 26
T402
K
K
R
A
M
Q
E
T
K
I
K
G
E
K
V
Site 27
T457
K
L
Q
E
D
K
P
T
F
K
K
E
E
I
K
Site 28
S480
E
P
K
E
E
V
K
S
F
M
D
R
K
K
G
Site 29
T489
M
D
R
K
K
G
F
T
E
V
K
S
Q
N
G
Site 30
S493
K
G
F
T
E
V
K
S
Q
N
G
E
F
M
T
Site 31
T509
K
L
K
H
T
E
N
T
F
S
R
P
G
G
R
Site 32
S511
K
H
T
E
N
T
F
S
R
P
G
G
R
A
S
Site 33
S518
S
R
P
G
G
R
A
S
V
D
T
K
E
A
E
Site 34
T521
G
G
R
A
S
V
D
T
K
E
A
E
G
A
P
Site 35
T546
L
R
R
R
R
G
E
T
E
S
E
E
F
E
K
Site 36
S548
R
R
R
G
E
T
E
S
E
E
F
E
K
L
K
Site 37
S628
K
M
P
E
D
G
L
S
D
D
K
K
P
F
K
Site 38
T638
K
K
P
F
K
C
F
T
P
K
G
S
S
L
K
Site 39
S643
C
F
T
P
K
G
S
S
L
K
I
E
E
R
A
Site 40
S656
R
A
E
F
L
N
K
S
V
Q
K
S
S
G
V
Site 41
S660
L
N
K
S
V
Q
K
S
S
G
V
K
S
T
H
Site 42
S661
N
K
S
V
Q
K
S
S
G
V
K
S
T
H
Q
Site 43
S665
Q
K
S
S
G
V
K
S
T
H
Q
A
A
I
V
Site 44
S673
T
H
Q
A
A
I
V
S
K
I
D
S
R
L
E
Site 45
S677
A
I
V
S
K
I
D
S
R
L
E
Q
Y
T
S
Site 46
Y682
I
D
S
R
L
E
Q
Y
T
S
A
I
E
G
T
Site 47
T683
D
S
R
L
E
Q
Y
T
S
A
I
E
G
T
K
Site 48
S684
S
R
L
E
Q
Y
T
S
A
I
E
G
T
K
S
Site 49
S691
S
A
I
E
G
T
K
S
A
K
P
T
K
P
A
Site 50
T695
G
T
K
S
A
K
P
T
K
P
A
A
S
D
L
Site 51
S700
K
P
T
K
P
A
A
S
D
L
P
V
P
A
E
Site 52
S714
E
G
V
R
N
I
K
S
M
W
E
K
G
N
V
Site 53
S723
W
E
K
G
N
V
F
S
S
P
T
A
A
G
T
Site 54
S724
E
K
G
N
V
F
S
S
P
T
A
A
G
T
P
Site 55
T726
G
N
V
F
S
S
P
T
A
A
G
T
P
N
K
Site 56
T730
S
S
P
T
A
A
G
T
P
N
K
E
T
A
G
Site 57
T735
A
G
T
P
N
K
E
T
A
G
L
K
V
G
V
Site 58
S744
G
L
K
V
G
V
S
S
R
I
N
E
W
L
T
Site 59
T751
S
R
I
N
E
W
L
T
K
T
P
D
G
N
K
Site 60
T753
I
N
E
W
L
T
K
T
P
D
G
N
K
S
P
Site 61
S759
K
T
P
D
G
N
K
S
P
A
P
K
P
S
D
Site 62
S765
K
S
P
A
P
K
P
S
D
L
R
P
G
D
V
Site 63
S773
D
L
R
P
G
D
V
S
S
K
R
N
L
W
E
Site 64
S774
L
R
P
G
D
V
S
S
K
R
N
L
W
E
K
Site 65
S783
R
N
L
W
E
K
Q
S
V
D
K
V
T
S
P
Site 66
T788
K
Q
S
V
D
K
V
T
S
P
T
K
V
_
_
Site 67
S789
Q
S
V
D
K
V
T
S
P
T
K
V
_
_
_
Site 68
T791
V
D
K
V
T
S
P
T
K
V
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation