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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB16
Full Name:
Zinc finger and BTB domain-containing protein 16
Alias:
kruppel-like zinc finger; plzf; promyelocytic leukemia zinc finger; zbt16; zbtb16; zinc finger and BTB domain containing 16; zinc finger and BTB domain-containing 16; zinc finger protein 145 (PLZF); znf145
Type:
Transcription, coactivator/corepressor
Mass (Da):
74274
Number AA:
673
UniProt ID:
Q05516
International Prot ID:
IPI00305613
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016605
GO:0016607
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0042803
GO:0016566
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007417
GO:0001823
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T50
Q
E
F
H
A
H
R
T
V
L
A
C
T
S
K
Site 2
Y70
F
H
R
N
S
Q
H
Y
T
L
D
F
L
S
P
Site 3
T71
H
R
N
S
Q
H
Y
T
L
D
F
L
S
P
K
Site 4
S76
H
Y
T
L
D
F
L
S
P
K
T
F
Q
Q
I
Site 5
T79
L
D
F
L
S
P
K
T
F
Q
Q
I
L
E
Y
Site 6
Y113
A
E
I
L
E
I
E
Y
L
E
E
Q
C
L
K
Site 7
T124
Q
C
L
K
M
L
E
T
I
Q
A
S
D
D
N
Site 8
T133
Q
A
S
D
D
N
D
T
E
A
T
M
A
D
G
Site 9
Y152
E
E
D
R
K
A
R
Y
L
K
N
I
F
I
S
Site 10
S159
Y
L
K
N
I
F
I
S
K
H
S
S
E
E
S
Site 11
S162
N
I
F
I
S
K
H
S
S
E
E
S
G
Y
A
Site 12
S163
I
F
I
S
K
H
S
S
E
E
S
G
Y
A
S
Site 13
S166
S
K
H
S
S
E
E
S
G
Y
A
S
V
A
G
Site 14
Y168
H
S
S
E
E
S
G
Y
A
S
V
A
G
Q
S
Site 15
S170
S
E
E
S
G
Y
A
S
V
A
G
Q
S
L
P
Site 16
S184
P
G
P
M
V
D
Q
S
P
S
V
S
T
S
F
Site 17
S186
P
M
V
D
Q
S
P
S
V
S
T
S
F
G
L
Site 18
S188
V
D
Q
S
P
S
V
S
T
S
F
G
L
S
A
Site 19
S190
Q
S
P
S
V
S
T
S
F
G
L
S
A
M
S
Site 20
S197
S
F
G
L
S
A
M
S
P
T
K
A
A
V
D
Site 21
S205
P
T
K
A
A
V
D
S
L
M
T
I
G
Q
S
Site 22
T217
G
Q
S
L
L
Q
G
T
L
Q
P
P
A
G
P
Site 23
T228
P
A
G
P
E
E
P
T
L
A
G
G
G
R
H
Site 24
S256
D
E
V
P
S
Q
D
S
P
G
A
A
E
S
S
Site 25
S262
D
S
P
G
A
A
E
S
S
I
S
G
G
M
G
Site 26
S263
S
P
G
A
A
E
S
S
I
S
G
G
M
G
D
Site 27
S265
G
A
A
E
S
S
I
S
G
G
M
G
D
K
V
Site 28
T282
R
G
K
E
G
P
G
T
P
T
R
S
S
V
I
Site 29
S286
G
P
G
T
P
T
R
S
S
V
I
T
S
A
R
Site 30
S287
P
G
T
P
T
R
S
S
V
I
T
S
A
R
E
Site 31
T290
P
T
R
S
S
V
I
T
S
A
R
E
L
H
Y
Site 32
S291
T
R
S
S
V
I
T
S
A
R
E
L
H
Y
G
Site 33
Y297
T
S
A
R
E
L
H
Y
G
R
E
E
S
A
E
Site 34
S302
L
H
Y
G
R
E
E
S
A
E
Q
V
P
P
P
Site 35
T317
A
E
A
G
Q
A
P
T
G
R
P
E
H
P
A
Site 36
Y334
P
E
K
H
L
G
I
Y
S
V
L
P
N
H
K
Site 37
S335
E
K
H
L
G
I
Y
S
V
L
P
N
H
K
A
Site 38
S347
H
K
A
D
A
V
L
S
M
P
S
S
V
T
S
Site 39
S354
S
M
P
S
S
V
T
S
G
L
H
V
Q
P
A
Site 40
S397
E
L
A
V
G
M
K
S
E
S
R
T
I
G
E
Site 41
S399
A
V
G
M
K
S
E
S
R
T
I
G
E
Q
C
Site 42
T401
G
M
K
S
E
S
R
T
I
G
E
Q
C
S
V
Site 43
T431
K
L
H
S
G
M
K
T
Y
G
C
E
L
C
G
Site 44
S444
C
G
K
R
F
L
D
S
L
R
L
R
M
H
L
Site 45
S471
D
Q
C
G
A
Q
F
S
K
E
D
A
L
E
T
Site 46
T478
S
K
E
D
A
L
E
T
H
R
Q
T
H
T
G
Site 47
T482
A
L
E
T
H
R
Q
T
H
T
G
T
D
M
A
Site 48
S503
G
K
R
F
Q
A
Q
S
A
L
Q
Q
H
M
E
Site 49
Y518
V
H
A
G
V
R
S
Y
I
C
S
E
C
N
R
Site 50
T526
I
C
S
E
C
N
R
T
F
P
S
H
T
A
L
Site 51
S529
E
C
N
R
T
F
P
S
H
T
A
L
K
R
H
Site 52
S539
A
L
K
R
H
L
R
S
H
T
G
D
H
P
Y
Site 53
T541
K
R
H
L
R
S
H
T
G
D
H
P
Y
E
C
Site 54
Y546
S
H
T
G
D
H
P
Y
E
C
E
F
C
G
S
Site 55
S559
G
S
C
F
R
D
E
S
T
L
K
S
H
K
R
Site 56
T560
S
C
F
R
D
E
S
T
L
K
S
H
K
R
I
Site 57
S563
R
D
E
S
T
L
K
S
H
K
R
I
H
T
G
Site 58
T569
K
S
H
K
R
I
H
T
G
E
K
P
Y
E
C
Site 59
Y574
I
H
T
G
E
K
P
Y
E
C
N
G
C
G
K
Site 60
S584
N
G
C
G
K
K
F
S
L
K
H
Q
L
E
T
Site 61
Y593
K
H
Q
L
E
T
H
Y
R
V
H
T
G
E
K
Site 62
T597
E
T
H
Y
R
V
H
T
G
E
K
P
F
E
C
Site 63
Y614
C
H
Q
R
S
R
D
Y
S
A
M
I
K
H
L
Site 64
S615
H
Q
R
S
R
D
Y
S
A
M
I
K
H
L
R
Site 65
T623
A
M
I
K
H
L
R
T
H
N
G
A
S
P
Y
Site 66
S643
T
E
Y
C
P
S
L
S
S
M
Q
K
H
M
K
Site 67
Y667
D
W
R
I
E
K
T
Y
L
Y
L
C
Y
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation