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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CACNB1
Full Name:
Voltage-dependent L-type calcium channel subunit beta-1
Alias:
CAB1; CACB1; CACNLB1; Calcium channel voltage-dependent subunit beta 1; Calcium channel, voltage-dependent, beta 1; Calcium channel, voltage-dependent, beta 1 subunit; Voltage-dependent L-type calcium channel beta-1
Type:
Channel protein, calcium
Mass (Da):
65714
Number AA:
598
UniProt ID:
Q02641
International Prot ID:
IPI00183965
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005891
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
Phosida
TranscriptoNet
STRING
Kinexus Products
Voltage-dependent L-type calcium channel subunit beta-1 pan-specific antibody AB-NN222-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN222-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
V
Q
K
T
S
M
S
R
G
P
Y
P
P
S
Site 2
Y12
T
S
M
S
R
G
P
Y
P
P
S
Q
E
I
P
Site 3
S15
S
R
G
P
Y
P
P
S
Q
E
I
P
M
E
V
Site 4
S26
P
M
E
V
F
D
P
S
P
Q
G
K
Y
S
K
Site 5
Y31
D
P
S
P
Q
G
K
Y
S
K
R
K
G
R
F
Site 6
S32
P
S
P
Q
G
K
Y
S
K
R
K
G
R
F
K
Site 7
S41
R
K
G
R
F
K
R
S
D
G
S
T
S
S
D
Site 8
S44
R
F
K
R
S
D
G
S
T
S
S
D
T
T
S
Site 9
T45
F
K
R
S
D
G
S
T
S
S
D
T
T
S
N
Site 10
S46
K
R
S
D
G
S
T
S
S
D
T
T
S
N
S
Site 11
S47
R
S
D
G
S
T
S
S
D
T
T
S
N
S
F
Site 12
T49
D
G
S
T
S
S
D
T
T
S
N
S
F
V
R
Site 13
T50
G
S
T
S
S
D
T
T
S
N
S
F
V
R
Q
Site 14
S51
S
T
S
S
D
T
T
S
N
S
F
V
R
Q
G
Site 15
S53
S
S
D
T
T
S
N
S
F
V
R
Q
G
S
A
Site 16
S59
N
S
F
V
R
Q
G
S
A
E
S
Y
T
S
R
Site 17
S62
V
R
Q
G
S
A
E
S
Y
T
S
R
P
S
D
Site 18
Y63
R
Q
G
S
A
E
S
Y
T
S
R
P
S
D
S
Site 19
T64
Q
G
S
A
E
S
Y
T
S
R
P
S
D
S
D
Site 20
S65
G
S
A
E
S
Y
T
S
R
P
S
D
S
D
V
Site 21
S68
E
S
Y
T
S
R
P
S
D
S
D
V
S
L
E
Site 22
S70
Y
T
S
R
P
S
D
S
D
V
S
L
E
E
D
Site 23
S73
R
P
S
D
S
D
V
S
L
E
E
D
R
E
A
Site 24
Y111
A
V
R
T
N
V
G
Y
N
P
S
P
G
D
E
Site 25
S114
T
N
V
G
Y
N
P
S
P
G
D
E
V
P
V
Site 26
S161
C
E
V
G
F
I
P
S
P
V
K
L
D
S
L
Site 27
S167
P
S
P
V
K
L
D
S
L
R
L
L
Q
E
Q
Site 28
S183
L
R
Q
N
R
L
G
S
S
K
S
G
D
N
S
Site 29
S184
R
Q
N
R
L
G
S
S
K
S
G
D
N
S
S
Site 30
S186
N
R
L
G
S
S
K
S
G
D
N
S
S
S
S
Site 31
S190
S
S
K
S
G
D
N
S
S
S
S
L
G
D
V
Site 32
S191
S
K
S
G
D
N
S
S
S
S
L
G
D
V
V
Site 33
S193
S
G
D
N
S
S
S
S
L
G
D
V
V
T
G
Site 34
T199
S
S
L
G
D
V
V
T
G
T
R
R
P
T
P
Site 35
T201
L
G
D
V
V
T
G
T
R
R
P
T
P
P
A
Site 36
T205
V
T
G
T
R
R
P
T
P
P
A
S
A
K
Q
Site 37
S209
R
R
P
T
P
P
A
S
A
K
Q
K
Q
K
S
Site 38
S216
S
A
K
Q
K
Q
K
S
T
E
H
V
P
P
Y
Site 39
Y223
S
T
E
H
V
P
P
Y
D
V
V
P
S
M
R
Site 40
Y242
V
G
P
S
L
K
G
Y
E
V
T
D
M
M
Q
Site 41
S265
H
R
F
D
G
R
I
S
I
T
R
V
T
A
D
Site 42
S279
D
I
S
L
A
K
R
S
V
L
N
N
P
S
K
Site 43
S293
K
H
I
I
I
E
R
S
N
T
R
S
S
L
A
Site 44
T295
I
I
I
E
R
S
N
T
R
S
S
L
A
E
V
Site 45
S297
I
E
R
S
N
T
R
S
S
L
A
E
V
Q
S
Site 46
S298
E
R
S
N
T
R
S
S
L
A
E
V
Q
S
E
Site 47
S304
S
S
L
A
E
V
Q
S
E
I
E
R
I
F
E
Site 48
S333
I
N
H
P
A
Q
L
S
K
T
S
L
A
P
I
Site 49
S348
I
V
Y
I
K
I
T
S
P
K
V
L
Q
R
L
Site 50
S358
V
L
Q
R
L
I
K
S
R
G
K
S
Q
S
K
Site 51
S362
L
I
K
S
R
G
K
S
Q
S
K
H
L
N
V
Site 52
S364
K
S
R
G
K
S
Q
S
K
H
L
N
V
Q
I
Site 53
Y404
A
C
E
H
L
A
E
Y
L
E
A
Y
W
K
A
Site 54
T412
L
E
A
Y
W
K
A
T
H
P
P
S
S
T
P
Site 55
S416
W
K
A
T
H
P
P
S
S
T
P
P
N
P
L
Site 56
S417
K
A
T
H
P
P
S
S
T
P
P
N
P
L
L
Site 57
T418
A
T
H
P
P
S
S
T
P
P
N
P
L
L
N
Site 58
S441
A
A
S
P
A
P
V
S
N
L
Q
G
P
Y
L
Site 59
T459
D
Q
P
L
E
R
A
T
G
E
H
A
S
M
H
Site 60
S464
R
A
T
G
E
H
A
S
M
H
E
Y
P
G
E
Site 61
Y468
E
H
A
S
M
H
E
Y
P
G
E
L
G
Q
P
Site 62
Y479
L
G
Q
P
P
G
L
Y
P
S
S
H
P
P
G
Site 63
S481
Q
P
P
G
L
Y
P
S
S
H
P
P
G
R
A
Site 64
S482
P
P
G
L
Y
P
S
S
H
P
P
G
R
A
G
Site 65
T490
H
P
P
G
R
A
G
T
L
R
A
L
S
R
Q
Site 66
S495
A
G
T
L
R
A
L
S
R
Q
D
T
F
D
A
Site 67
T499
R
A
L
S
R
Q
D
T
F
D
A
D
T
P
G
Site 68
T504
Q
D
T
F
D
A
D
T
P
G
S
R
N
S
A
Site 69
S507
F
D
A
D
T
P
G
S
R
N
S
A
Y
T
E
Site 70
S510
D
T
P
G
S
R
N
S
A
Y
T
E
L
G
D
Site 71
Y512
P
G
S
R
N
S
A
Y
T
E
L
G
D
S
C
Site 72
T513
G
S
R
N
S
A
Y
T
E
L
G
D
S
C
V
Site 73
S518
A
Y
T
E
L
G
D
S
C
V
D
M
E
T
D
Site 74
T524
D
S
C
V
D
M
E
T
D
P
S
E
G
P
G
Site 75
S527
V
D
M
E
T
D
P
S
E
G
P
G
L
G
D
Site 76
T540
G
D
P
A
G
G
G
T
P
P
A
R
Q
G
S
Site 77
S547
T
P
P
A
R
Q
G
S
W
E
D
E
E
E
D
Site 78
Y555
W
E
D
E
E
E
D
Y
E
E
E
L
T
D
N
Site 79
T560
E
D
Y
E
E
E
L
T
D
N
R
N
R
G
R
Site 80
Y572
R
G
R
N
K
A
R
Y
C
A
E
G
G
G
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation