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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLI1
Full Name:
Friend leukemia integration 1 transcription factor
Alias:
ERGB transcription factor; EWSR2; Fli-1 proto-oncogene; Friend leukemia virus integration 1; SIC-1; Transcription factor ERGB
Type:
Transcription protein
Mass (Da):
50982
Number AA:
452
UniProt ID:
Q01543
International Prot ID:
IPI00217470
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007599
GO:0009887
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
G
T
I
K
E
A
L
S
V
V
S
D
D
Q
S
Site 2
S13
K
E
A
L
S
V
V
S
D
D
Q
S
L
F
D
Site 3
S17
S
V
V
S
D
D
Q
S
L
F
D
S
A
Y
G
Site 4
S21
D
D
Q
S
L
F
D
S
A
Y
G
A
A
A
H
Site 5
T35
H
L
P
K
A
D
M
T
A
S
G
S
P
D
Y
Site 6
S37
P
K
A
D
M
T
A
S
G
S
P
D
Y
G
Q
Site 7
S39
A
D
M
T
A
S
G
S
P
D
Y
G
Q
P
H
Site 8
Y42
T
A
S
G
S
P
D
Y
G
Q
P
H
K
I
N
Site 9
Y70
R
V
N
V
K
R
E
Y
D
H
M
N
G
S
R
Site 10
S76
E
Y
D
H
M
N
G
S
R
E
S
P
V
D
C
Site 11
S79
H
M
N
G
S
R
E
S
P
V
D
C
S
V
S
Site 12
S84
R
E
S
P
V
D
C
S
V
S
K
C
S
K
L
Site 13
S86
S
P
V
D
C
S
V
S
K
C
S
K
L
V
G
Site 14
S89
D
C
S
V
S
K
C
S
K
L
V
G
G
G
E
Site 15
Y102
G
E
S
N
P
M
N
Y
N
S
Y
M
D
E
K
Site 16
S150
E
W
A
I
K
E
Y
S
L
M
E
I
D
T
S
Site 17
T179
K
E
D
F
L
R
A
T
T
L
Y
N
T
E
V
Site 18
T180
E
D
F
L
R
A
T
T
L
Y
N
T
E
V
L
Site 19
S189
Y
N
T
E
V
L
L
S
H
L
S
Y
L
R
E
Site 20
S197
H
L
S
Y
L
R
E
S
S
L
L
A
Y
N
T
Site 21
S198
L
S
Y
L
R
E
S
S
L
L
A
Y
N
T
T
Site 22
Y202
R
E
S
S
L
L
A
Y
N
T
T
S
H
T
D
Site 23
T204
S
S
L
L
A
Y
N
T
T
S
H
T
D
Q
S
Site 24
S206
L
L
A
Y
N
T
T
S
H
T
D
Q
S
S
R
Site 25
T208
A
Y
N
T
T
S
H
T
D
Q
S
S
R
L
S
Site 26
S211
T
T
S
H
T
D
Q
S
S
R
L
S
V
K
E
Site 27
S212
T
S
H
T
D
Q
S
S
R
L
S
V
K
E
D
Site 28
S215
T
D
Q
S
S
R
L
S
V
K
E
D
P
S
Y
Site 29
S221
L
S
V
K
E
D
P
S
Y
D
S
V
R
R
G
Site 30
Y222
S
V
K
E
D
P
S
Y
D
S
V
R
R
G
A
Site 31
S224
K
E
D
P
S
Y
D
S
V
R
R
G
A
W
G
Site 32
S236
A
W
G
N
N
M
N
S
G
L
N
K
S
P
P
Site 33
S241
M
N
S
G
L
N
K
S
P
P
L
G
G
A
Q
Site 34
T249
P
P
L
G
G
A
Q
T
I
S
K
N
T
E
Q
Site 35
S251
L
G
G
A
Q
T
I
S
K
N
T
E
Q
R
P
Site 36
Y263
Q
R
P
Q
P
D
P
Y
Q
I
L
G
P
T
S
Site 37
S270
Y
Q
I
L
G
P
T
S
S
R
L
A
N
P
G
Site 38
S271
Q
I
L
G
P
T
S
S
R
L
A
N
P
G
S
Site 39
S278
S
R
L
A
N
P
G
S
G
Q
I
Q
L
W
Q
Site 40
S298
L
S
D
S
A
N
A
S
C
I
T
W
E
G
T
Site 41
T312
T
N
G
E
F
K
M
T
D
P
D
E
V
A
R
Site 42
Y332
K
S
K
P
N
M
N
Y
D
K
L
S
R
A
L
Site 43
Y342
L
S
R
A
L
R
Y
Y
Y
D
K
N
I
M
T
Site 44
Y343
S
R
A
L
R
Y
Y
Y
D
K
N
I
M
T
K
Site 45
Y356
T
K
V
H
G
K
R
Y
A
Y
K
F
D
F
H
Site 46
Y358
V
H
G
K
R
Y
A
Y
K
F
D
F
H
G
I
Site 47
T374
Q
A
L
Q
P
H
P
T
E
S
S
M
Y
K
Y
Site 48
S377
Q
P
H
P
T
E
S
S
M
Y
K
Y
P
S
D
Site 49
Y379
H
P
T
E
S
S
M
Y
K
Y
P
S
D
I
S
Site 50
Y381
T
E
S
S
M
Y
K
Y
P
S
D
I
S
Y
M
Site 51
S383
S
S
M
Y
K
Y
P
S
D
I
S
Y
M
P
S
Site 52
Y387
K
Y
P
S
D
I
S
Y
M
P
S
Y
H
A
H
Site 53
Y391
D
I
S
Y
M
P
S
Y
H
A
H
Q
Q
K
V
Site 54
S406
N
F
V
P
P
H
P
S
S
M
P
V
T
S
S
Site 55
S407
F
V
P
P
H
P
S
S
M
P
V
T
S
S
S
Site 56
T411
H
P
S
S
M
P
V
T
S
S
S
F
F
G
A
Site 57
S420
S
S
F
F
G
A
A
S
Q
Y
W
T
S
P
T
Site 58
Y422
F
F
G
A
A
S
Q
Y
W
T
S
P
T
G
G
Site 59
T424
G
A
A
S
Q
Y
W
T
S
P
T
G
G
I
Y
Site 60
S425
A
A
S
Q
Y
W
T
S
P
T
G
G
I
Y
P
Site 61
Y431
T
S
P
T
G
G
I
Y
P
N
P
N
V
P
R
Site 62
T442
N
V
P
R
H
P
N
T
H
V
P
S
H
L
G
Site 63
S450
H
V
P
S
H
L
G
S
Y
Y
_
_
_
_
_
Site 64
Y451
V
P
S
H
L
G
S
Y
Y
_
_
_
_
_
_
Site 65
Y452
P
S
H
L
G
S
Y
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation