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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SET
Full Name:
Protein SET
Alias:
IGAAD; PHAPII; Phosphatase 2A inhibitor I2PP2A; TAF-I; TAF-I beta
Type:
Inhibitor protein; Apoptosis; DNA binding protein; DNA replication
Mass (Da):
33489
Number AA:
290
UniProt ID:
Q01105
International Prot ID:
IPI00301311
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0004857
GO:0004864
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006259
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
P
K
R
Q
S
P
L
P
P
Q
K
K
Site 2
S30
G
P
E
E
T
S
A
S
A
G
L
P
K
K
G
Site 3
S63
D
R
L
N
E
Q
A
S
E
E
I
L
K
V
E
Site 4
Y119
E
D
E
E
A
L
H
Y
L
T
R
V
E
V
T
Site 5
Y140
S
G
Y
R
I
D
F
Y
F
D
E
N
P
Y
F
Site 6
Y146
F
Y
F
D
E
N
P
Y
F
E
N
K
V
L
S
Site 7
S153
Y
F
E
N
K
V
L
S
K
E
F
H
L
N
E
Site 8
S161
K
E
F
H
L
N
E
S
G
D
P
S
S
K
S
Site 9
S165
L
N
E
S
G
D
P
S
S
K
S
T
E
I
K
Site 10
S166
N
E
S
G
D
P
S
S
K
S
T
E
I
K
W
Site 11
S168
S
G
D
P
S
S
K
S
T
E
I
K
W
K
S
Site 12
T169
G
D
P
S
S
K
S
T
E
I
K
W
K
S
G
Site 13
S175
S
T
E
I
K
W
K
S
G
K
D
L
T
K
R
Site 14
T180
W
K
S
G
K
D
L
T
K
R
S
S
Q
T
Q
Site 15
S184
K
D
L
T
K
R
S
S
Q
T
Q
N
K
A
S
Site 16
S191
S
Q
T
Q
N
K
A
S
R
K
R
Q
H
E
E
Site 17
S210
F
T
W
F
T
D
H
S
D
A
G
A
D
E
L
Site 18
Y233
W
P
N
P
L
Q
Y
Y
L
V
P
D
M
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation