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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RACK1
Full Name:
Guanine nucleotide-binding protein subunit beta-2-like 1
Alias:
Cell proliferation-inducing gene 21 protein; GBLP; GNB2L1; GNB2-RS1; Guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1; Guanine nucleotide-binding protein beta subunit-like protein 12.3; H12.3; Human lung cancer oncogene 7 protein; P205; Receptor for activated C kinase; Receptor for Activated C Kinase 1; Receptor of activated protein kinase C 1
Type:
Nuclear receptor co-regulator; Adaptor/scaffold
Mass (Da):
35077
Number AA:
317
UniProt ID:
P63244
International Prot ID:
IPI00641950
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043025
GO:0005737
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0019903
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0007205
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
E
Q
M
T
L
R
G
Site 2
T6
_
_
M
T
E
Q
M
T
L
R
G
T
L
K
G
Site 3
T10
E
Q
M
T
L
R
G
T
L
K
G
H
N
G
W
Site 4
T19
K
G
H
N
G
W
V
T
Q
I
A
T
T
P
Q
Site 5
S33
Q
F
P
D
M
I
L
S
A
S
R
D
K
T
I
Site 6
T39
L
S
A
S
R
D
K
T
I
I
M
W
K
L
T
Site 7
T46
T
I
I
M
W
K
L
T
R
D
E
T
N
Y
G
Site 8
T50
W
K
L
T
R
D
E
T
N
Y
G
I
P
Q
R
Site 9
Y52
L
T
R
D
E
T
N
Y
G
I
P
Q
R
A
L
Site 10
S63
Q
R
A
L
R
G
H
S
H
F
V
S
D
V
V
Site 11
S67
R
G
H
S
H
F
V
S
D
V
V
I
S
S
D
Site 12
S80
S
D
G
Q
F
A
L
S
G
S
W
D
G
T
L
Site 13
S82
G
Q
F
A
L
S
G
S
W
D
G
T
L
R
L
Site 14
T86
L
S
G
S
W
D
G
T
L
R
L
W
D
L
T
Site 15
T93
T
L
R
L
W
D
L
T
T
G
T
T
T
R
R
Site 16
T94
L
R
L
W
D
L
T
T
G
T
T
T
R
R
F
Site 17
T97
W
D
L
T
T
G
T
T
T
R
R
F
V
G
H
Site 18
T98
D
L
T
T
G
T
T
T
R
R
F
V
G
H
T
Site 19
T105
T
R
R
F
V
G
H
T
K
D
V
L
S
V
A
Site 20
S110
G
H
T
K
D
V
L
S
V
A
F
S
S
D
N
Site 21
S122
S
D
N
R
Q
I
V
S
G
S
R
D
K
T
I
Site 22
T128
V
S
G
S
R
D
K
T
I
K
L
W
N
T
L
Site 23
Y140
N
T
L
G
V
C
K
Y
T
V
Q
D
E
S
H
Site 24
T141
T
L
G
V
C
K
Y
T
V
Q
D
E
S
H
S
Site 25
S146
K
Y
T
V
Q
D
E
S
H
S
E
W
V
S
C
Site 26
S148
T
V
Q
D
E
S
H
S
E
W
V
S
C
V
R
Site 27
S152
E
S
H
S
E
W
V
S
C
V
R
F
S
P
N
Site 28
S157
W
V
S
C
V
R
F
S
P
N
S
S
N
P
I
Site 29
S161
V
R
F
S
P
N
S
S
N
P
I
I
V
S
C
Site 30
Y194
N
H
I
G
H
T
G
Y
L
N
T
V
T
V
S
Site 31
T197
G
H
T
G
Y
L
N
T
V
T
V
S
P
D
G
Site 32
T199
T
G
Y
L
N
T
V
T
V
S
P
D
G
S
L
Site 33
S209
P
D
G
S
L
C
A
S
G
G
K
D
G
Q
A
Site 34
Y228
L
N
E
G
K
H
L
Y
T
L
D
G
G
D
I
Site 35
Y246
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
G
Site 36
S276
E
L
K
Q
E
V
I
S
T
S
S
K
A
E
P
Site 37
T277
L
K
Q
E
V
I
S
T
S
S
K
A
E
P
P
Site 38
S278
K
Q
E
V
I
S
T
S
S
K
A
E
P
P
Q
Site 39
S279
Q
E
V
I
S
T
S
S
K
A
E
P
P
Q
C
Site 40
S288
A
E
P
P
Q
C
T
S
L
A
W
S
A
D
G
Site 41
S292
Q
C
T
S
L
A
W
S
A
D
G
Q
T
L
F
Site 42
T297
A
W
S
A
D
G
Q
T
L
F
A
G
Y
T
D
Site 43
Y302
G
Q
T
L
F
A
G
Y
T
D
N
L
V
R
V
Site 44
T313
L
V
R
V
W
Q
V
T
I
G
T
R
_
_
_
Site 45
T316
V
W
Q
V
T
I
G
T
R
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation