PhosphoNET

           
Protein Info 
   
Short Name:  hnRNP K
Full Name:  Heterogeneous nuclear ribonucleoprotein K
Alias:  65 kDa phosphoprotein; CSBP; DC-stretch binding protein; HNRNPK; HnRNP-K; HNRPK; Transformation upregulated nuclear protein; TUNP
Type:  RNA binding protein
Mass (Da):  50976
Number AA:  463
UniProt ID:  P61978
International Prot ID:  IPI00216049
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0030530  GO:0005654 Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0003723  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0044419  GO:0000398  GO:0007165 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T3_____METEQPEETF
Site 2T9ETEQPEETFPNTETN
Site 3T13PEETFPNTETNGEFG
Site 4S36EEQAFKRSRNTDEMV
Site 5T39AFKRSRNTDEMVELR
Site 6Y72IKALRTDYNASVSVP
Site 7S75LRTDYNASVSVPDSS
Site 8S77TDYNASVSVPDSSGP
Site 9S81ASVSVPDSSGPERIL
Site 10S82SVSVPDSSGPERILS
Site 11S89SGPERILSISADIET
Site 12T107ILKKIIPTLEEGLQL
Site 13S116EEGLQLPSPTATSQL
Site 14T118GLQLPSPTATSQLPL
Site 15T120QLPSPTATSQLPLES
Site 16S121LPSPTATSQLPLESD
Site 17S127TSQLPLESDAVECLN
Site 18Y135DAVECLNYQHYKGSD
Site 19Y138ECLNYQHYKGSDFDC
Site 20S141NYQHYKGSDFDCELR
Site 21T174IKELRENTQTTIKLF
Site 22T176ELRENTQTTIKLFQE
Site 23T189QECCPHSTDRVVLIG
Site 24S214KIILDLISESPIKGR
Site 25S216ILDLISESPIKGRAQ
Site 26Y225IKGRAQPYDPNFYDE
Site 27Y230QPYDPNFYDETYDYG
Site 28Y234PNFYDETYDYGGFTM
Site 29Y236FYDETYDYGGFTMMF
Site 30S276GGRPMPPSRRDYDDM
Site 31Y280MPPSRRDYDDMSPRR
Site 32S284RRDYDDMSPRRGPPP
Site 33S302GRGGRGGSRARNLPL
Site 34Y323RGGDLMAYDRRGRPG
Site 35Y333RGRPGDRYDGMVGFS
Site 36T344VGFSADETWDSAIDT
Site 37S347SADETWDSAIDTWSP
Site 38S353DSAIDTWSPSEWQMA
Site 39Y361PSEWQMAYEPQGGSG
Site 40Y369EPQGGSGYDYSYAGG
Site 41Y371QGGSGYDYSYAGGRG
Site 42S372GGSGYDYSYAGGRGS
Site 43Y373GSGYDYSYAGGRGSY
Site 44S379SYAGGRGSYGDLGGP
Site 45Y380YAGGRGSYGDLGGPI
Site 46T390LGGPIITTQVTIPKD
Site 47S401IPKDLAGSIIGKGGQ
Site 48S417IKQIRHESGASIKID
Site 49T436GSEDRIITITGTQDQ
Site 50T438EDRIITITGTQDQIQ
Site 51T440RIITITGTQDQIQNA
Site 52Y449DQIQNAQYLLQNSVK
Site 53S454AQYLLQNSVKQYSGK
Site 54Y458LQNSVKQYSGKFF__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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