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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DLX5
Full Name:
Homeobox protein DLX-5
Alias:
Distal-less homeo box 5
Type:
Cytoplasm, Nucleolus, Nucleus protein
Mass (Da):
31540
Number AA:
289
UniProt ID:
P56178
International Prot ID:
IPI00008192
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0001501
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
F
D
R
R
V
P
S
I
R
S
G
D
F
Q
Site 2
S31
S
A
A
M
H
H
P
S
Q
E
S
P
T
L
P
Site 3
S34
M
H
H
P
S
Q
E
S
P
T
L
P
E
S
S
Site 4
T36
H
P
S
Q
E
S
P
T
L
P
E
S
S
A
T
Site 5
S40
E
S
P
T
L
P
E
S
S
A
T
D
S
D
Y
Site 6
S41
S
P
T
L
P
E
S
S
A
T
D
S
D
Y
Y
Site 7
T43
T
L
P
E
S
S
A
T
D
S
D
Y
Y
S
P
Site 8
S45
P
E
S
S
A
T
D
S
D
Y
Y
S
P
T
G
Site 9
Y47
S
S
A
T
D
S
D
Y
Y
S
P
T
G
G
A
Site 10
Y48
S
A
T
D
S
D
Y
Y
S
P
T
G
G
A
P
Site 11
S49
A
T
D
S
D
Y
Y
S
P
T
G
G
A
P
H
Site 12
Y58
T
G
G
A
P
H
G
Y
C
S
P
T
S
A
S
Site 13
S60
G
A
P
H
G
Y
C
S
P
T
S
A
S
Y
G
Site 14
S63
H
G
Y
C
S
P
T
S
A
S
Y
G
K
A
L
Site 15
S65
Y
C
S
P
T
S
A
S
Y
G
K
A
L
N
P
Site 16
Y73
Y
G
K
A
L
N
P
Y
Q
Y
Q
Y
H
G
V
Site 17
Y75
K
A
L
N
P
Y
Q
Y
Q
Y
H
G
V
N
G
Site 18
Y77
L
N
P
Y
Q
Y
Q
Y
H
G
V
N
G
S
A
Site 19
S83
Q
Y
H
G
V
N
G
S
A
G
S
Y
P
A
K
Site 20
Y87
V
N
G
S
A
G
S
Y
P
A
K
A
Y
A
D
Site 21
Y92
G
S
Y
P
A
K
A
Y
A
D
Y
S
Y
A
S
Site 22
Y95
P
A
K
A
Y
A
D
Y
S
Y
A
S
S
Y
H
Site 23
S96
A
K
A
Y
A
D
Y
S
Y
A
S
S
Y
H
Q
Site 24
Y97
K
A
Y
A
D
Y
S
Y
A
S
S
Y
H
Q
Y
Site 25
S100
A
D
Y
S
Y
A
S
S
Y
H
Q
Y
G
G
A
Site 26
Y101
D
Y
S
Y
A
S
S
Y
H
Q
Y
G
G
A
Y
Site 27
Y108
Y
H
Q
Y
G
G
A
Y
N
R
V
P
S
A
T
Site 28
S113
G
A
Y
N
R
V
P
S
A
T
N
Q
P
E
K
Site 29
T115
Y
N
R
V
P
S
A
T
N
Q
P
E
K
E
V
Site 30
T123
N
Q
P
E
K
E
V
T
E
P
E
V
R
M
V
Site 31
T142
K
K
V
R
K
P
R
T
I
Y
S
S
F
Q
L
Site 32
Y144
V
R
K
P
R
T
I
Y
S
S
F
Q
L
A
A
Site 33
S145
R
K
P
R
T
I
Y
S
S
F
Q
L
A
A
L
Site 34
S146
K
P
R
T
I
Y
S
S
F
Q
L
A
A
L
Q
Site 35
T159
L
Q
R
R
F
Q
K
T
Q
Y
L
A
L
P
E
Site 36
Y161
R
R
F
Q
K
T
Q
Y
L
A
L
P
E
R
A
Site 37
S173
E
R
A
E
L
A
A
S
L
G
L
T
Q
T
Q
Site 38
S206
G
E
M
P
P
E
H
S
P
S
S
S
D
P
M
Site 39
S208
M
P
P
E
H
S
P
S
S
S
D
P
M
A
C
Site 40
S209
P
P
E
H
S
P
S
S
S
D
P
M
A
C
N
Site 41
S210
P
E
H
S
P
S
S
S
D
P
M
A
C
N
S
Site 42
S217
S
D
P
M
A
C
N
S
P
Q
S
P
A
V
W
Site 43
S220
M
A
C
N
S
P
Q
S
P
A
V
W
E
P
Q
Site 44
S229
A
V
W
E
P
Q
G
S
S
R
S
L
S
H
H
Site 45
S230
V
W
E
P
Q
G
S
S
R
S
L
S
H
H
P
Site 46
S232
E
P
Q
G
S
S
R
S
L
S
H
H
P
H
A
Site 47
S234
Q
G
S
S
R
S
L
S
H
H
P
H
A
H
P
Site 48
T243
H
P
H
A
H
P
P
T
S
N
Q
S
P
A
S
Site 49
S244
P
H
A
H
P
P
T
S
N
Q
S
P
A
S
S
Site 50
S247
H
P
P
T
S
N
Q
S
P
A
S
S
Y
L
E
Site 51
S250
T
S
N
Q
S
P
A
S
S
Y
L
E
N
S
A
Site 52
S251
S
N
Q
S
P
A
S
S
Y
L
E
N
S
A
S
Site 53
Y252
N
Q
S
P
A
S
S
Y
L
E
N
S
A
S
W
Site 54
S256
A
S
S
Y
L
E
N
S
A
S
W
Y
T
S
A
Site 55
S258
S
Y
L
E
N
S
A
S
W
Y
T
S
A
A
S
Site 56
Y260
L
E
N
S
A
S
W
Y
T
S
A
A
S
S
I
Site 57
S262
N
S
A
S
W
Y
T
S
A
A
S
S
I
N
S
Site 58
S265
S
W
Y
T
S
A
A
S
S
I
N
S
H
L
P
Site 59
S266
W
Y
T
S
A
A
S
S
I
N
S
H
L
P
P
Site 60
S269
S
A
A
S
S
I
N
S
H
L
P
P
P
G
S
Site 61
S276
S
H
L
P
P
P
G
S
L
Q
H
P
L
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation