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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RAD23B
Full Name:
UV excision repair protein RAD23 homolog B
Alias:
HHR23B; HR23B; P58; RAD23 homologue B; RD23B; XP-C repair-complementing complex 58 kDa protein
Type:
Mediator of proteosomal degradation of misfolded proteins and DNA repair
Mass (Da):
43171
Number AA:
409
UniProt ID:
P54727
International Prot ID:
IPI00008223
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005654
GO:0000502
Uniprot
OncoNet
Molecular Function:
GO:0003684
GO:0005515
GO:0003697
PhosphoSite+
KinaseNET
Biological Process:
GO:0000718
GO:0043161
GO:0006139
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
Q
V
T
L
K
T
L
Q
Q
Q
T
F
K
Site 2
S32
A
L
K
E
K
I
E
S
E
K
G
K
D
A
F
Site 3
T57
G
K
I
L
N
D
D
T
A
L
K
E
Y
K
I
Site 4
T82
T
K
P
K
A
V
S
T
P
A
P
A
T
T
Q
Site 5
T87
V
S
T
P
A
P
A
T
T
Q
Q
S
A
P
A
Site 6
T88
S
T
P
A
P
A
T
T
Q
Q
S
A
P
A
S
Site 7
S91
A
P
A
T
T
Q
Q
S
A
P
A
S
T
T
A
Site 8
S95
T
Q
Q
S
A
P
A
S
T
T
A
V
T
S
S
Site 9
T97
Q
S
A
P
A
S
T
T
A
V
T
S
S
T
T
Site 10
S102
S
T
T
A
V
T
S
S
T
T
T
T
V
A
Q
Site 11
T106
V
T
S
S
T
T
T
T
V
A
Q
A
P
T
P
Site 12
S125
A
P
T
S
T
P
A
S
I
T
P
A
S
A
T
Site 13
T127
T
S
T
P
A
S
I
T
P
A
S
A
T
A
S
Site 14
S130
P
A
S
I
T
P
A
S
A
T
A
S
S
E
P
Site 15
T132
S
I
T
P
A
S
A
T
A
S
S
E
P
A
P
Site 16
S134
T
P
A
S
A
T
A
S
S
E
P
A
P
A
S
Site 17
S135
P
A
S
A
T
A
S
S
E
P
A
P
A
S
A
Site 18
S141
S
S
E
P
A
P
A
S
A
A
K
Q
E
K
P
Site 19
T155
P
A
E
K
P
A
E
T
P
V
A
T
S
P
T
Site 20
T159
P
A
E
T
P
V
A
T
S
P
T
A
T
D
S
Site 21
S160
A
E
T
P
V
A
T
S
P
T
A
T
D
S
T
Site 22
T162
T
P
V
A
T
S
P
T
A
T
D
S
T
S
G
Site 23
T164
V
A
T
S
P
T
A
T
D
S
T
S
G
D
S
Site 24
S166
T
S
P
T
A
T
D
S
T
S
G
D
S
S
R
Site 25
T167
S
P
T
A
T
D
S
T
S
G
D
S
S
R
S
Site 26
S168
P
T
A
T
D
S
T
S
G
D
S
S
R
S
N
Site 27
S171
T
D
S
T
S
G
D
S
S
R
S
N
L
F
E
Site 28
S172
D
S
T
S
G
D
S
S
R
S
N
L
F
E
D
Site 29
T181
S
N
L
F
E
D
A
T
S
A
L
V
T
G
Q
Site 30
S182
N
L
F
E
D
A
T
S
A
L
V
T
G
Q
S
Site 31
T186
D
A
T
S
A
L
V
T
G
Q
S
Y
E
N
M
Site 32
S189
S
A
L
V
T
G
Q
S
Y
E
N
M
V
T
E
Site 33
Y202
T
E
I
M
S
M
G
Y
E
R
E
Q
V
I
A
Site 34
S214
V
I
A
A
L
R
A
S
F
N
N
P
D
R
A
Site 35
Y224
N
P
D
R
A
V
E
Y
L
L
M
G
I
P
G
Site 36
S235
G
I
P
G
D
R
E
S
Q
A
V
V
D
P
P
Site 37
T247
D
P
P
Q
A
A
S
T
G
A
P
Q
S
S
A
Site 38
T267
A
T
T
T
A
T
T
T
T
T
S
S
G
G
H
Site 39
S271
A
T
T
T
T
T
S
S
G
G
H
P
L
E
F
Site 40
S318
P
Q
L
L
Q
Q
I
S
Q
H
Q
E
H
F
I
Site 41
S346
G
G
G
G
G
G
G
S
G
G
I
A
E
A
G
Site 42
Y359
A
G
S
G
H
M
N
Y
I
Q
V
T
P
Q
E
Site 43
T363
H
M
N
Y
I
Q
V
T
P
Q
E
K
E
A
I
Site 44
Y387
E
G
L
V
I
Q
A
Y
F
A
C
E
K
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation