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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARFIP2
Full Name:
Arfaptin-2
Alias:
ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; Arfaptin 2; ARFP2; Partner of RAC1; POR1; POR1 protein
Type:
GTPase activating protein, Rac/Rho; Motility/polarity/chemotaxis
Mass (Da):
37856
Number AA:
341
UniProt ID:
P53365
International Prot ID:
IPI00021257
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005938
GO:0005886
GO:0001726
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0030742
GO:0048365
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0006928
GO:0030032
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T48
S
G
P
N
L
N
E
T
S
I
V
S
G
G
Y
Site 2
S49
G
P
N
L
N
E
T
S
I
V
S
G
G
Y
G
Site 3
T65
S
G
D
G
L
I
P
T
G
S
G
R
H
P
S
Site 4
S67
D
G
L
I
P
T
G
S
G
R
H
P
S
H
S
Site 5
S72
T
G
S
G
R
H
P
S
H
S
T
T
P
S
G
Site 6
S74
S
G
R
H
P
S
H
S
T
T
P
S
G
P
G
Site 7
T75
G
R
H
P
S
H
S
T
T
P
S
G
P
G
D
Site 8
T76
R
H
P
S
H
S
T
T
P
S
G
P
G
D
E
Site 9
S78
P
S
H
S
T
T
P
S
G
P
G
D
E
V
A
Site 10
Y104
K
K
W
G
I
N
T
Y
K
C
T
K
Q
L
L
Site 11
S112
K
C
T
K
Q
L
L
S
E
R
F
G
R
G
S
Site 12
S119
S
E
R
F
G
R
G
S
R
T
V
D
L
E
L
Site 13
T121
R
F
G
R
G
S
R
T
V
D
L
E
L
E
L
Site 14
T136
Q
I
E
L
L
R
E
T
K
R
K
Y
E
S
V
Site 15
Y140
L
R
E
T
K
R
K
Y
E
S
V
L
Q
L
G
Site 16
S142
E
T
K
R
K
Y
E
S
V
L
Q
L
G
R
A
Site 17
Y155
R
A
L
T
A
H
L
Y
S
L
L
Q
T
Q
H
Site 18
T160
H
L
Y
S
L
L
Q
T
Q
H
A
L
G
D
A
Site 19
S172
G
D
A
F
A
D
L
S
Q
K
S
P
E
L
Q
Site 20
S175
F
A
D
L
S
Q
K
S
P
E
L
Q
E
E
F
Site 21
Y184
E
L
Q
E
E
F
G
Y
N
A
E
T
Q
K
L
Site 22
T221
V
T
K
T
M
E
D
T
L
M
T
V
K
Q
Y
Site 23
Y235
Y
E
A
A
R
L
E
Y
D
A
Y
R
T
D
L
Site 24
Y238
A
R
L
E
Y
D
A
Y
R
T
D
L
E
E
L
Site 25
S246
R
T
D
L
E
E
L
S
L
G
P
R
D
A
G
Site 26
T254
L
G
P
R
D
A
G
T
R
G
R
L
E
S
A
Site 27
S260
G
T
R
G
R
L
E
S
A
Q
A
T
F
Q
A
Site 28
T264
R
L
E
S
A
Q
A
T
F
Q
A
H
R
D
K
Site 29
Y272
F
Q
A
H
R
D
K
Y
E
K
L
R
G
D
V
Site 30
Y308
F
H
N
A
V
S
A
Y
F
A
G
N
Q
K
Q
Site 31
S336
P
P
G
A
E
K
P
S
W
L
E
E
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation