PhosphoNET

           
Protein Info 
   
Short Name:  ASCL1
Full Name:  Achaete-scute homolog 1
Alias:  Class A basic helix-loop-helix protein 46
Type: 
Mass (Da):  25454
Number AA:  236
UniProt ID:  P50553
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S81PSGGGHKSAPKQVKR
Site 2S91KQVKRQRSSSPELMR
Site 3S92QVKRQRSSSPELMRC
Site 4S93VKRQRSSSPELMRCK
Site 5S106CKRRLNFSGFGYSLP
Site 6Y110LNFSGFGYSLPQQQP
Site 7S111NFSGFGYSLPQQQPA
Site 8T159KKMSKVETLRSAVEY
Site 9S162SKVETLRSAVEYIRA
Site 10T192QAGVLSPTISPNYSN
Site 11S194GVLSPTISPNYSNDL
Site 12Y197SPTISPNYSNDLNSM
Site 13S198PTISPNYSNDLNSMA
Site 14S203NYSNDLNSMAGSPVS
Site 15S207DLNSMAGSPVSSYSS
Site 16S210SMAGSPVSSYSSDEG
Site 17S211MAGSPVSSYSSDEGS
Site 18Y212AGSPVSSYSSDEGSY
Site 19S213GSPVSSYSSDEGSYD
Site 20S214SPVSSYSSDEGSYDP
Site 21S218SYSSDEGSYDPLSPE
Site 22Y219YSSDEGSYDPLSPEE
Site 23S223EGSYDPLSPEEQELL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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