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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPT1A
Full Name:
Carnitine O-palmitoyltransferase 1, liver isoform
Alias:
Carnitine O-palmitoyltransferase I, liver isoform; Carnitine palmitoyltransferase 1A (liver); CPT I; CPT1; CPT1-L; CPTI-L; EC 2.3.1.21; L-CPT1
Type:
EC 2.3.1.21; Transferase; Lipid Metabolism - fatty acid
Mass (Da):
88368
Number AA:
773
UniProt ID:
P50416
International Prot ID:
IPI00032038
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005741
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0004095
PhosphoSite+
KinaseNET
Biological Process:
GO:0006635
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
D
G
I
D
L
R
L
S
H
E
A
L
R
Q
I
Site 2
Y32
H
E
A
L
R
Q
I
Y
L
S
G
L
H
S
W
Site 3
S34
A
L
R
Q
I
Y
L
S
G
L
H
S
W
K
K
Site 4
S38
I
Y
L
S
G
L
H
S
W
K
K
K
F
I
R
Site 5
Y55
N
G
I
I
T
G
V
Y
P
A
S
P
S
S
W
Site 6
S99
E
T
A
N
C
M
S
S
Q
T
K
N
V
V
S
Site 7
S106
S
Q
T
K
N
V
V
S
G
V
L
F
G
T
G
Site 8
Y165
S
G
R
K
P
M
L
Y
S
F
Q
T
S
L
P
Site 9
S166
G
R
K
P
M
L
Y
S
F
Q
T
S
L
P
R
Site 10
T182
P
V
P
A
V
K
D
T
V
N
R
Y
L
Q
S
Site 11
Y186
V
K
D
T
V
N
R
Y
L
Q
S
V
R
P
L
Site 12
S189
T
V
N
R
Y
L
Q
S
V
R
P
L
M
K
E
Site 13
T203
E
E
D
F
K
R
M
T
A
L
A
Q
D
F
A
Site 14
Y220
L
G
P
R
L
Q
W
Y
L
K
L
K
S
W
W
Site 15
Y239
V
S
D
W
W
E
E
Y
I
Y
L
R
G
R
G
Site 16
Y241
D
W
W
E
E
Y
I
Y
L
R
G
R
G
P
L
Site 17
Y282
A
I
H
A
I
L
L
Y
R
R
K
L
D
R
E
Site 18
S315
W
E
R
M
F
N
T
S
R
I
P
G
E
E
T
Site 19
T324
I
P
G
E
E
T
D
T
I
Q
H
M
R
D
S
Site 20
Y337
D
S
K
H
I
V
V
Y
H
R
G
R
Y
F
K
Site 21
Y342
V
V
Y
H
R
G
R
Y
F
K
V
W
L
Y
H
Site 22
Y348
R
Y
F
K
V
W
L
Y
H
D
G
R
L
L
K
Site 23
T370
M
Q
R
I
L
D
N
T
S
E
P
Q
P
G
E
Site 24
S371
Q
R
I
L
D
N
T
S
E
P
Q
P
G
E
A
Site 25
T384
E
A
R
L
A
A
L
T
A
G
D
R
V
P
W
Site 26
Y398
W
A
R
C
R
Q
A
Y
F
G
R
G
K
N
K
Site 27
S407
G
R
G
K
N
K
Q
S
L
D
A
V
E
K
A
Site 28
T423
F
F
V
T
L
D
E
T
E
E
G
Y
R
S
E
Site 29
S429
E
T
E
E
G
Y
R
S
E
D
P
D
T
S
M
Site 30
T434
Y
R
S
E
D
P
D
T
S
M
D
S
Y
A
K
Site 31
S435
R
S
E
D
P
D
T
S
M
D
S
Y
A
K
S
Site 32
S438
D
P
D
T
S
M
D
S
Y
A
K
S
L
L
H
Site 33
Y439
P
D
T
S
M
D
S
Y
A
K
S
L
L
H
G
Site 34
S442
S
M
D
S
Y
A
K
S
L
L
H
G
R
C
Y
Site 35
Y449
S
L
L
H
G
R
C
Y
D
R
W
F
D
K
S
Site 36
S493
E
Y
V
M
S
I
D
S
L
Q
L
G
Y
A
E
Site 37
Y514
D
I
N
P
N
I
P
Y
P
T
R
L
Q
W
D
Site 38
T532
E
C
Q
E
V
I
E
T
S
L
N
T
A
N
L
Site 39
T588
D
M
G
K
F
C
L
T
Y
E
A
S
M
T
R
Site 40
S592
F
C
L
T
Y
E
A
S
M
T
R
L
F
R
E
Site 41
T594
L
T
Y
E
A
S
M
T
R
L
F
R
E
G
R
Site 42
T604
F
R
E
G
R
T
E
T
V
R
S
C
T
T
E
Site 43
S607
G
R
T
E
T
V
R
S
C
T
T
E
S
C
D
Site 44
T609
T
E
T
V
R
S
C
T
T
E
S
C
D
F
V
Site 45
S637
L
K
L
F
K
L
A
S
E
K
H
Q
H
M
Y
Site 46
S651
Y
R
L
A
M
T
G
S
G
I
D
R
H
L
F
Site 47
S679
P
F
L
K
E
V
L
S
E
P
W
R
L
S
T
Site 48
S685
L
S
E
P
W
R
L
S
T
S
Q
T
P
Q
Q
Site 49
T686
S
E
P
W
R
L
S
T
S
Q
T
P
Q
Q
Q
Site 50
S687
E
P
W
R
L
S
T
S
Q
T
P
Q
Q
Q
V
Site 51
T689
W
R
L
S
T
S
Q
T
P
Q
Q
Q
V
E
L
Site 52
Y705
D
L
E
N
N
P
E
Y
V
S
S
G
G
G
F
Site 53
S708
N
N
P
E
Y
V
S
S
G
G
G
F
G
P
V
Site 54
S723
A
D
D
G
Y
G
V
S
Y
I
L
V
G
E
N
Site 55
S741
F
H
I
S
S
K
F
S
C
P
E
T
D
S
H
Site 56
T745
S
K
F
S
C
P
E
T
D
S
H
R
F
G
R
Site 57
S747
F
S
C
P
E
T
D
S
H
R
F
G
R
H
L
Site 58
S769
I
T
L
F
G
L
S
S
N
S
K
K
_
_
_
Site 59
S771
L
F
G
L
S
S
N
S
K
K
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation