PhosphoNET

           
Protein Info 
   
Short Name:  GMPS
Full Name:  GMP synthase [glutamine-hydrolyzing]
Alias:  Glutamine amidotransferase; GMP synthetase; GUAA; Guanine monphosphate synthetase
Type:  EC 6.3.5.2; Ligase; Nucleotide Metabolism - purine; Xenobiotic Metabolism - drug metabolism - other enzymes
Mass (Da):  76715
Number AA:  693
UniProt ID:  P49915
International Prot ID:  IPI00029079
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0044424  GO:0044464 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0003922  GO:0003921 PhosphoSite+ KinaseNET
Biological Process:  GO:0006177  GO:0006541  GO:0009113 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MALCNGDSKLENAGG
Site 2Y24LKDGHHHYEGAVVIL
Site 3S80IISGGPNSVYAEDAP
Site 4Y82SGGPNSVYAEDAPWF
Site 5S122GGTVHKKSVREDGVF
Site 6S132EDGVFNISVDNTCSL
Site 7S138ISVDNTCSLFRGLQK
Site 8T152KEEVVLLTHGDSVDK
Site 9Y185ANESKKLYGAQFHPE
Site 10T216DIAGCSGTFTVQNRE
Site 11T218AGCSGTFTVQNRELE
Site 12T253GVDSTVCTALLNRAL
Site 13S280GFMRKRESQSVEEAL
Site 14S282MRKRESQSVEEALKK
Site 15S302KVINAAHSFYNGTTT
Site 16T309SFYNGTTTLPISDED
Site 17S313GTTTLPISDEDRTPR
Site 18T318PISDEDRTPRKRISK
Site 19S324RTPRKRISKTLNMTT
Site 20T326PRKRISKTLNMTTSP
Site 21T330ISKTLNMTTSPEEKR
Site 22T331SKTLNMTTSPEEKRK
Site 23S332KTLNMTTSPEEKRKI
Site 24T343KRKIIGDTFVKIANE
Site 25T390GKAELIKTHHNDTEL
Site 26S434GLPEELVSRHPFPGP
Site 27Y454VICAEEPYICKDFPE
Site 28S473LKIVADFSASVKKPH
Site 29T481ASVKKPHTLLQRVKA
Site 30T490LQRVKACTTEEDQEK
Site 31Y526VQGDCRSYSYVCGIS
Site 32S527QGDCRSYSYVCGISS
Site 33Y528GDCRSYSYVCGISSK
Site 34S534SYVCGISSKDEPDWE
Site 35S542KDEPDWESLIFLARL
Site 36T573PPVKEPPTDVTPTFL
Site 37T576KEPPTDVTPTFLTTG
Site 38S602AHNILRESGYAGKIS
Site 39Y604NILRESGYAGKISQM
Site 40T616SQMPVILTPLHFDRD
Site 41S630DPLQKQPSCQRSVVI
Site 42S634KQPSCQRSVVIRTFI
Site 43Y680PGISRIMYDLTSKPP
Site 44T683SRIMYDLTSKPPGTT
Site 45S684RIMYDLTSKPPGTTE
Site 46T689LTSKPPGTTEWE___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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