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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGS4
Full Name:
Regulator of G-protein signaling 4
Alias:
Type:
GTPase-activating protein for G protein
Mass (Da):
23256
Number AA:
205
UniProt ID:
P49798
International Prot ID:
IPI00028112
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0005516
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0000188
GO:0009968
GO:0008277
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
L
P
A
S
C
L
R
S
A
K
D
M
K
H
R
Site 2
S30
L
G
F
L
L
Q
K
S
D
S
C
E
H
N
S
Site 3
S32
F
L
L
Q
K
S
D
S
C
E
H
N
S
S
H
Site 4
S38
D
S
C
E
H
N
S
S
H
N
K
K
D
K
V
Site 5
S52
V
V
I
C
Q
R
V
S
Q
E
E
V
K
K
W
Site 6
S62
E
V
K
K
W
A
E
S
L
E
N
L
I
S
H
Site 7
S82
A
F
K
A
F
L
K
S
E
Y
S
E
E
N
I
Site 8
S85
A
F
L
K
S
E
Y
S
E
E
N
I
D
F
W
Site 9
Y98
F
W
I
S
C
E
E
Y
K
K
I
K
S
P
S
Site 10
S103
E
E
Y
K
K
I
K
S
P
S
K
L
S
P
K
Site 11
S108
I
K
S
P
S
K
L
S
P
K
A
K
K
I
Y
Site 12
Y115
S
P
K
A
K
K
I
Y
N
E
F
I
S
V
Q
Site 13
T124
E
F
I
S
V
Q
A
T
K
E
V
N
L
D
S
Site 14
S131
T
K
E
V
N
L
D
S
C
T
R
E
E
T
S
Site 15
T133
E
V
N
L
D
S
C
T
R
E
E
T
S
R
N
Site 16
T137
D
S
C
T
R
E
E
T
S
R
N
M
L
E
P
Site 17
T147
N
M
L
E
P
T
I
T
C
F
D
E
A
Q
K
Site 18
S164
F
N
L
M
E
K
D
S
Y
R
R
F
L
K
S
Site 19
Y165
N
L
M
E
K
D
S
Y
R
R
F
L
K
S
R
Site 20
S171
S
Y
R
R
F
L
K
S
R
F
Y
L
D
L
V
Site 21
Y174
R
F
L
K
S
R
F
Y
L
D
L
V
N
P
S
Site 22
S182
L
D
L
V
N
P
S
S
C
G
A
E
K
Q
K
Site 23
S193
E
K
Q
K
G
A
K
S
S
A
D
C
A
S
L
Site 24
S194
K
Q
K
G
A
K
S
S
A
D
C
A
S
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation