PhosphoNET

           
Protein Info 
   
Short Name:  HINT1
Full Name:  Histidine triad nucleotide-binding protein 1
Alias:  Adenosine 5'-monophosphoramidase; HINT; Histidine triad nucleotide binding protein 1; Histidine triad nucleotide-binding 1; PKCI1; PKCI-1; PRKCNH1; Protein kinase C inhibitor 1; Protein kinase C-interacting 1
Type:  Cytoskeletal protein; Hydrolase; Tumor suppressor; EC 3.-.-.-
Mass (Da):  13671
Number AA:  125
UniProt ID:  P49773
International Prot ID:  IPI00239077
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005856  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0016787  GO:0005080   PhosphoSite+ KinaseNET
Biological Process:  GO:0007165     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S61VIPKKHISQISVAED
Site 2Y94DLGLNKGYRMVVNEG
Site 3S102RMVVNEGSDGGQSVY
Site 4S107EGSDGGQSVYHVHLH
Site 5Y109SDGGQSVYHVHLHVL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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