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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GluR4
Full Name:
Glutamate receptor 4
Alias:
AMPA-selective glutamate receptor 4; GLR4; GLUR4; GluR-4; GLURD; GluR-D; Glutamate receptor ionotropic, AMPA 4; Glutamate receptor, ionotrophic, AMPA 4; GRIA4
Type:
Channel, ligand-gated
Mass (Da):
100871
Number AA:
902
UniProt ID:
P48058
International Prot ID:
IPI00007632
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0030666
GO:0045211
Uniprot
OncoNet
Molecular Function:
GO:0005234
PhosphoSite+
KinaseNET
Biological Process:
GO:0007215
GO:0006811
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
G
G
L
F
I
R
N
T
D
Q
E
Y
T
A
F
Site 2
Y41
I
R
N
T
D
Q
E
Y
T
A
F
R
L
A
I
Site 3
S54
A
I
F
L
H
N
T
S
P
N
A
S
E
A
P
Site 4
S58
H
N
T
S
P
N
A
S
E
A
P
F
N
L
V
Site 5
S76
D
N
I
E
T
A
N
S
F
A
V
T
N
A
F
Site 6
S102
F
G
L
Y
D
K
R
S
V
H
T
L
T
S
F
Site 7
T107
K
R
S
V
H
T
L
T
S
F
C
S
A
L
H
Site 8
S121
H
I
S
L
I
T
P
S
F
P
T
E
G
E
S
Site 9
S128
S
F
P
T
E
G
E
S
Q
F
V
L
Q
L
R
Site 10
S144
S
L
R
G
A
L
L
S
L
L
D
H
Y
E
W
Site 11
Y164
L
Y
D
T
D
R
G
Y
S
I
L
Q
A
I
M
Site 12
S165
Y
D
T
D
R
G
Y
S
I
L
Q
A
I
M
E
Site 13
S193
V
E
N
F
N
D
V
S
Y
R
Q
L
L
E
E
Site 14
Y194
E
N
F
N
D
V
S
Y
R
Q
L
L
E
E
L
Site 15
Y237
K
H
V
K
G
Y
H
Y
I
I
A
N
L
G
F
Site 16
S248
N
L
G
F
K
D
I
S
L
E
R
F
I
H
G
Site 17
Y287
K
K
L
D
Q
R
E
Y
P
G
S
E
T
P
P
Site 18
S290
D
Q
R
E
Y
P
G
S
E
T
P
P
K
Y
T
Site 19
T292
R
E
Y
P
G
S
E
T
P
P
K
Y
T
S
A
Site 20
Y296
G
S
E
T
P
P
K
Y
T
S
A
L
T
Y
D
Site 21
T311
G
V
L
V
M
A
E
T
F
R
S
L
R
R
Q
Site 22
S314
V
M
A
E
T
F
R
S
L
R
R
Q
K
I
D
Site 23
S323
R
R
Q
K
I
D
I
S
R
R
G
N
A
G
D
Site 24
T348
Q
G
I
D
M
E
R
T
L
K
Q
V
R
I
Q
Site 25
T358
Q
V
R
I
Q
G
L
T
G
N
V
Q
F
D
H
Site 26
Y366
G
N
V
Q
F
D
H
Y
G
R
R
V
N
Y
T
Site 27
Y372
H
Y
G
R
R
V
N
Y
T
M
D
V
F
E
L
Site 28
T373
Y
G
R
R
V
N
Y
T
M
D
V
F
E
L
K
Site 29
S381
M
D
V
F
E
L
K
S
T
G
P
R
K
V
G
Site 30
T382
D
V
F
E
L
K
S
T
G
P
R
K
V
G
Y
Site 31
Y389
T
G
P
R
K
V
G
Y
W
N
D
M
D
K
L
Site 32
T420
E
N
R
T
V
V
V
T
T
I
M
E
S
P
Y
Site 33
Y427
T
T
I
M
E
S
P
Y
V
M
Y
K
K
N
H
Site 34
Y443
M
F
E
G
N
D
K
Y
E
G
Y
C
V
D
L
Site 35
Y446
G
N
D
K
Y
E
G
Y
C
V
D
L
A
S
E
Site 36
Y472
A
I
V
P
D
G
K
Y
G
A
R
D
A
D
T
Site 37
S514
R
E
E
V
I
D
F
S
K
P
F
M
S
L
G
Site 38
S532
M
I
K
K
P
Q
K
S
K
P
G
V
F
S
F
Site 39
S538
K
S
K
P
G
V
F
S
F
L
D
P
L
A
Y
Site 40
Y545
S
F
L
D
P
L
A
Y
E
I
W
M
C
I
V
Site 41
S569
L
F
L
V
S
R
F
S
P
Y
E
W
H
T
E
Site 42
T575
F
S
P
Y
E
W
H
T
E
E
P
E
D
G
K
Site 43
S586
E
D
G
K
E
G
P
S
D
Q
P
P
N
E
F
Site 44
S614
M
Q
Q
G
C
D
I
S
P
R
S
L
S
G
R
Site 45
S617
G
C
D
I
S
P
R
S
L
S
G
R
I
V
G
Site 46
S653
L
T
V
E
R
M
V
S
P
I
E
S
A
E
D
Site 47
S657
R
M
V
S
P
I
E
S
A
E
D
L
A
K
Q
Site 48
S674
I
A
Y
G
T
L
D
S
G
S
T
K
E
F
F
Site 49
S676
Y
G
T
L
D
S
G
S
T
K
E
F
F
R
R
Site 50
S684
T
K
E
F
F
R
R
S
K
I
A
V
Y
E
K
Site 51
Y689
R
R
S
K
I
A
V
Y
E
K
M
W
T
Y
M
Site 52
Y695
V
Y
E
K
M
W
T
Y
M
R
S
A
E
P
S
Site 53
S702
Y
M
R
S
A
E
P
S
V
F
T
R
T
T
A
Site 54
S718
G
V
A
R
V
R
K
S
K
G
K
F
A
F
L
Site 55
T742
E
Q
R
K
P
C
D
T
M
K
V
G
G
N
L
Site 56
S751
K
V
G
G
N
L
D
S
K
G
Y
G
V
A
T
Site 57
T758
S
K
G
Y
G
V
A
T
P
K
G
S
S
L
R
Site 58
S763
V
A
T
P
K
G
S
S
L
R
T
P
V
N
L
Site 59
Y790
K
L
K
N
K
W
W
Y
D
K
G
E
C
G
P
Site 60
S800
G
E
C
G
P
K
D
S
G
S
K
D
K
T
S
Site 61
S802
C
G
P
K
D
S
G
S
K
D
K
T
S
A
L
Site 62
T806
D
S
G
S
K
D
K
T
S
A
L
S
L
S
N
Site 63
S807
S
G
S
K
D
K
T
S
A
L
S
L
S
N
V
Site 64
S810
K
D
K
T
S
A
L
S
L
S
N
V
A
G
V
Site 65
Y838
V
A
L
I
E
F
C
Y
K
S
R
A
E
A
K
Site 66
S840
L
I
E
F
C
Y
K
S
R
A
E
A
K
R
M
Site 67
T850
E
A
K
R
M
K
L
T
F
S
E
A
I
R
N
Site 68
S852
K
R
M
K
L
T
F
S
E
A
I
R
N
K
A
Site 69
S862
I
R
N
K
A
R
L
S
I
T
G
S
V
G
E
Site 70
T864
N
K
A
R
L
S
I
T
G
S
V
G
E
N
G
Site 71
S866
A
R
L
S
I
T
G
S
V
G
E
N
G
R
V
Site 72
T875
G
E
N
G
R
V
L
T
P
D
C
P
K
A
V
Site 73
T886
P
K
A
V
H
T
G
T
A
I
R
Q
S
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation