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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ROMK
Full Name:
ATP-sensitive inward rectifier potassium channel 1
Alias:
ATP-regulated potassium channel ROM-K; IRK1; KAB-1; KCNJ1; Kir1.1; Potassium channel, inwardly rectifying, subfamily J, member 1; potassium inwardly-rectifying channel, subfamily J, member 1; ROMK1
Type:
Channel, potassium
Mass (Da):
44795
Number AA:
391
UniProt ID:
P48048
International Prot ID:
IPI00007612
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005242
GO:0030955
PhosphoSite+
KinaseNET
Biological Process:
GO:0007588
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
N
A
S
S
R
N
V
F
D
T
Site 2
T11
S
S
R
N
V
F
D
T
L
I
R
V
L
T
E
Site 3
S19
L
I
R
V
L
T
E
S
M
F
K
H
L
R
K
Site 4
S36
V
T
R
F
F
G
H
S
R
Q
R
A
R
L
V
Site 5
S44
R
Q
R
A
R
L
V
S
K
D
G
R
C
N
I
Site 6
T119
F
H
P
S
A
N
H
T
P
C
V
E
N
I
N
Site 7
S183
G
A
I
L
A
K
I
S
R
P
K
K
R
A
K
Site 8
T191
R
P
K
K
R
A
K
T
I
T
F
S
K
N
A
Site 9
T193
K
K
R
A
K
T
I
T
F
S
K
N
A
V
I
Site 10
S195
R
A
K
T
I
T
F
S
K
N
A
V
I
S
K
Site 11
S201
F
S
K
N
A
V
I
S
K
R
G
G
K
L
C
Site 12
S219
R
V
A
N
L
R
K
S
L
L
I
G
S
H
I
Site 13
T234
Y
G
K
L
L
K
T
T
V
T
P
E
G
E
T
Site 14
T307
T
V
E
S
T
S
A
T
C
Q
V
R
T
S
Y
Site 15
S313
A
T
C
Q
V
R
T
S
Y
V
P
E
E
V
L
Site 16
Y314
T
C
Q
V
R
T
S
Y
V
P
E
E
V
L
W
Site 17
T332
F
A
P
I
V
S
K
T
K
E
G
K
Y
R
V
Site 18
Y337
S
K
T
K
E
G
K
Y
R
V
D
F
H
N
F
Site 19
T347
D
F
H
N
F
S
K
T
V
E
V
E
T
P
H
Site 20
Y360
P
H
C
A
M
C
L
Y
N
E
K
D
V
R
A
Site 21
Y373
R
A
R
M
K
R
G
Y
D
N
P
N
F
I
L
Site 22
S381
D
N
P
N
F
I
L
S
E
V
N
E
T
D
D
Site 23
T386
I
L
S
E
V
N
E
T
D
D
T
K
M
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation