PhosphoNET

           
Protein Info 
   
Short Name:  MAP1B
Full Name:  Microtubule-associated protein 1B
Alias:  MAP1 light chain LC1; MAP1(X); MAP1.2; MTAP1B; MTAP5; Neuraxin
Type:  Cytoskeletal protein - microtubule dynamics
Mass (Da):  270620
Number AA:  2468
UniProt ID:  P46821
International Prot ID:  IPI00008868
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005874  GO:0005875   Uniprot OncoNet
Molecular Function:  GO:0005198    GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0016358  GO:0001578   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T9ATVVVEATEPEPSGS
Site 2S14EATEPEPSGSIANPA
Site 3S16TEPEPSGSIANPAAS
Site 4S23SIANPAASTSPSLSH
Site 5T24IANPAASTSPSLSHR
Site 6S25ANPAASTSPSLSHRF
Site 7S27PAASTSPSLSHRFLD
Site 8S29ASTSPSLSHRFLDSK
Site 9S84QELKLFVSRHSARFS
Site 10S87KLFVSRHSARFSPEV
Site 11S91SRHSARFSPEVPGQK
Site 12S104QKILHHRSDVLETVV
Site 13T122PSDEAVSTEVRLMIT
Site 14T129TEVRLMITDAARHKL
Site 15S154TGELILQSGSFSFQN
Site 16S176QEIGELLSTTHPANK
Site 17T177EIGELLSTTHPANKA
Site 18T187PANKASLTLFCPEEG
Site 19S218NIKLNSASILPEMEG
Site 20S227LPEMEGLSEFTEYLS
Site 21Y232GLSEFTEYLSESVEV
Site 22S234SEFTEYLSESVEVPS
Site 23S236FTEYLSESVEVPSPF
Site 24S241SESVEVPSPFDILEP
Site 25S251DILEPPTSGGFLKLS
Site 26Y263KLSKPCCYIFPGGRG
Site 27S292NGGSERKSCFWKLIR
Site 28S306RHLDRVDSILLTHIG
Site 29T310RVDSILLTHIGDDNL
Site 30S336AELEEEQSQGSTTNS
Site 31S339EEEQSQGSTTNSDWM
Site 32T340EEQSQGSTTNSDWMK
Site 33S343SQGSTTNSDWMKNLI
Site 34S377PNIKMKRSIEEACFT
Site 35Y387EACFTLQYLNKLSMK
Site 36S392LQYLNKLSMKPEPLF
Site 37S401KPEPLFRSVGNTIDP
Site 38S430YVLNPVKSSKEMQYF
Site 39Y436KSSKEMQYFMQQWTG
Site 40S464QEVDLPISYLTSVSS
Site 41S493RVLFPGNSTQYNILE
Site 42Y496FPGNSTQYNILEGLE
Site 43T522LATQKDLTGQVPTPV
Site 44T527DLTGQVPTPVVKQTK
Site 45S541KLKQRADSRESLKPA
Site 46S544QRADSRESLKPAAKP
Site 47S554PAAKPLPSKSVRKES
Site 48S556AKPLPSKSVRKESKE
Site 49S561SKSVRKESKEETPEV
Site 50T565RKESKEETPEVTKVN
Site 51T569KEETPEVTKVNHVEK
Site 52T596KKDKPVKTETKPSVT
Site 53S601VKTETKPSVTEKEVP
Site 54S609VTEKEVPSKEEPSPV
Site 55S614VPSKEEPSPVKAEVA
Site 56T626EVAEKQATDVKPKAA
Site 57T637PKAAKEKTVKKETKV
Site 58T667VAKKEDKTPIKKEEK
Site 59T704KKEVKKETPPKEVKK
Site 60S742LPKDAKKSSTPLSEA
Site 61S743PKDAKKSSTPLSEAK
Site 62T744KDAKKSSTPLSEAKK
Site 63S747KKSSTPLSEAKKPAA
Site 64S765KVPKKEESVKKDSVA
Site 65S770EESVKKDSVAAGKPK
Site 66S828KELEAERSLMSSPED
Site 67S831EAERSLMSSPEDLTK
Site 68S832AERSLMSSPEDLTKD
Site 69T837MSSPEDLTKDFEELK
Site 70T851KAEEVDVTKDIKPQL
Site 71Y876ETEPVEAYVIQKERE
Site 72T885IQKEREVTKGPAESP
Site 73S891VTKGPAESPDEGITT
Site 74T898SPDEGITTTEGEGEC
Site 75T899PDEGITTTEGEGECE
Site 76T908GEGECEQTPEELEPV
Site 77S936EGAGFEESSETGDYE
Site 78S937GAGFEESSETGDYEE
Site 79T939GFEESSETGDYEEKA
Site 80Y942ESSETGDYEEKAETE
Site 81T948DYEEKAETEEAEEPE
Site 82S965GEEHVCVSASKHSPT
Site 83S967EHVCVSASKHSPTED
Site 84S970CVSASKHSPTEDEES
Site 85T972SASKHSPTEDEESAK
Site 86S977SPTEDEESAKAEADA
Site 87Y985AKAEADAYIREKRES
Site 88S992YIREKRESVASGDDR
Site 89S995EKRESVASGDDRAEE
Site 90S1016EKGEAEQSEEEADEE
Site 91Y1044EKMEAEDYVMAVVDK
Site 92Y1062AGGAEEQYGFLTTPT
Site 93T1066EEQYGFLTTPTKQLG
Site 94T1067EQYGFLTTPTKQLGA
Site 95T1069YGFLTTPTKQLGAQS
Site 96S1076TKQLGAQSPGREPAS
Site 97S1083SPGREPASSIHDETL
Site 98S1084PGREPASSIHDETLP
Site 99T1089ASSIHDETLPGGSES
Site 100S1096TLPGGSESEATASDE
Site 101T1099GGSESEATASDEENR
Site 102S1101SESEATASDEENRED
Site 103T1116QPEEFTATSGYTQST
Site 104S1117PEEFTATSGYTQSTI
Site 105S1122ATSGYTQSTIEISSE
Site 106T1123TSGYTQSTIEISSEP
Site 107T1131IEISSEPTPMDEMST
Site 108S1137PTPMDEMSTPRDVMS
Site 109T1138TPMDEMSTPRDVMSD
Site 110S1144STPRDVMSDETNNEE
Site 111T1147RDVMSDETNNEETES
Site 112T1152DETNNEETESPSQEF
Site 113S1154TNNEETESPSQEFVN
Site 114S1156NEETESPSQEFVNIT
Site 115T1163SQEFVNITKYESSLY
Site 116Y1165EFVNITKYESSLYSQ
Site 117S1168NITKYESSLYSQEYS
Site 118Y1170TKYESSLYSQEYSKP
Site 119S1171KYESSLYSQEYSKPA
Site 120Y1174SSLYSQEYSKPADVT
Site 121S1175SLYSQEYSKPADVTP
Site 122T1181YSKPADVTPLNGFSE
Site 123S1187VTPLNGFSEGSKTDA
Site 124T1192GFSEGSKTDATDGKD
Site 125T1195EGSKTDATDGKDYNA
Site 126Y1200DATDGKDYNASASTI
Site 127S1203DGKDYNASASTISPP
Site 128S1205KDYNASASTISPPSS
Site 129T1206DYNASASTISPPSSM
Site 130S1208NASASTISPPSSMEE
Site 131S1211ASTISPPSSMEEDKF
Site 132S1212STISPPSSMEEDKFS
Site 133S1219SMEEDKFSRSALRDA
Site 134Y1227RSALRDAYCSEVKAS
Site 135S1229ALRDAYCSEVKASTT
Site 136T1236SEVKASTTLDIKDSI
Site 137S1242TTLDIKDSISAVSSE
Site 138S1244LDIKDSISAVSSEKV
Site 139S1247KDSISAVSSEKVSPS
Site 140S1248DSISAVSSEKVSPSK
Site 141S1252AVSSEKVSPSKSPSL
Site 142S1254SSEKVSPSKSPSLSP
Site 143S1256EKVSPSKSPSLSPSP
Site 144S1258VSPSKSPSLSPSPPS
Site 145S1260PSKSPSLSPSPPSPL
Site 146S1262KSPSLSPSPPSPLEK
Site 147S1265SLSPSPPSPLEKTPL
Site 148T1270PPSPLEKTPLGERSV
Site 149S1276KTPLGERSVNFSLTP
Site 150S1280GERSVNFSLTPNEIK
Site 151T1282RSVNFSLTPNEIKVS
Site 152S1289TPNEIKVSAEAEVAP
Site 153S1298EAEVAPVSPEVTQEV
Site 154T1302APVSPEVTQEVVEEH
Site 155S1312VVEEHCASPEDKTLE
Site 156T1317CASPEDKTLEVVSPS
Site 157S1322DKTLEVVSPSQSVTG
Site 158S1324TLEVVSPSQSVTGSA
Site 159S1326EVVSPSQSVTGSAGH
Site 160T1328VSPSQSVTGSAGHTP
Site 161S1330PSQSVTGSAGHTPYY
Site 162T1334VTGSAGHTPYYQSPT
Site 163Y1336GSAGHTPYYQSPTDE
Site 164Y1337SAGHTPYYQSPTDEK
Site 165S1339GHTPYYQSPTDEKSS
Site 166T1341TPYYQSPTDEKSSHL
Site 167S1345QSPTDEKSSHLPTEV
Site 168S1346SPTDEKSSHLPTEVI
Site 169T1350EKSSHLPTEVIEKPP
Site 170S1362KPPAVPVSFEFSDAK
Site 171S1366VPVSFEFSDAKDENE
Site 172S1376KDENERASVSPMDEP
Site 173S1378ENERASVSPMDEPVP
Site 174S1387MDEPVPDSESPIEKV
Site 175S1389EPVPDSESPIEKVLS
Site 176S1396SPIEKVLSPLRSPPL
Site 177S1400KVLSPLRSPPLIGSE
Site 178S1406RSPPLIGSESAYESF
Site 179S1408PPLIGSESAYESFLS
Site 180Y1410LIGSESAYESFLSAD
Site 181S1412GSESAYESFLSADDK
Site 182S1415SAYESFLSADDKASG
Site 183S1421LSADDKASGRGAESP
Site 184S1427ASGRGAESPFEEKSG
Site 185S1433ESPFEEKSGKQGSPD
Site 186S1438EKSGKQGSPDQVSPV
Site 187S1443QGSPDQVSPVSEMTS
Site 188S1446PDQVSPVSEMTSTSL
Site 189T1449VSPVSEMTSTSLYQD
Site 190S1450SPVSEMTSTSLYQDK
Site 191T1451PVSEMTSTSLYQDKQ
Site 192S1452VSEMTSTSLYQDKQE
Site 193Y1454EMTSTSLYQDKQEGK
Site 194T1478DFGQEKKTDDVEAMS
Site 195S1486DDVEAMSSQPALALD
Site 196S1501ERKLGDVSPTQIDVS
Site 197T1503KLGDVSPTQIDVSQF
Site 198S1508SPTQIDVSQFGSFKE
Site 199S1512IDVSQFGSFKEDTKM
Site 200T1517FGSFKEDTKMSISEG
Site 201S1520FKEDTKMSISEGTVS
Site 202T1525KMSISEGTVSDKSAT
Site 203S1527SISEGTVSDKSATPV
Site 204S1530EGTVSDKSATPVDEG
Site 205T1532TVSDKSATPVDEGVA
Site 206T1542DEGVAEDTYSHMEGV
Site 207Y1543EGVAEDTYSHMEGVA
Site 208S1544GVAEDTYSHMEGVAS
Site 209S1560STASVATSSFPEPTT
Site 210S1561TASVATSSFPEPTTD
Site 211T1567SSFPEPTTDDVSPSL
Site 212S1571EPTTDDVSPSLHAEV
Site 213S1573TTDDVSPSLHAEVGS
Site 214S1580SLHAEVGSPHSTEVD
Site 215S1583AEVGSPHSTEVDDSL
Site 216T1584EVGSPHSTEVDDSLS
Site 217S1589HSTEVDDSLSVSVVQ
Site 218S1591TEVDDSLSVSVVQTP
Site 219T1600SVVQTPTTFQETEMS
Site 220S1607TFQETEMSPSKEECP
Site 221S1609QETEMSPSKEECPRP
Site 222S1618EECPRPMSISPPDFS
Site 223S1620CPRPMSISPPDFSPK
Site 224S1625SISPPDFSPKTAKSR
Site 225T1628PPDFSPKTAKSRTPV
Site 226S1631FSPKTAKSRTPVQDH
Site 227T1633PKTAKSRTPVQDHRS
Site 228S1640TPVQDHRSEQSSMSI
Site 229S1644DHRSEQSSMSIEFGQ
Site 230S1646RSEQSSMSIEFGQES
Site 231S1653SIEFGQESPEQSLAM
Site 232S1657GQESPEQSLAMDFSR
Site 233S1663QSLAMDFSRQSPDHP
Site 234S1666AMDFSRQSPDHPTVG
Site 235T1671RQSPDHPTVGAGVLH
Site 236T1680GAGVLHITENGPTEV
Site 237T1685HITENGPTEVDYSPS
Site 238Y1689NGPTEVDYSPSDMQD
Site 239S1690GPTEVDYSPSDMQDS
Site 240S1692TEVDYSPSDMQDSSL
Site 241S1697SPSDMQDSSLSHKIP
Site 242S1698PSDMQDSSLSHKIPP
Site 243S1700DMQDSSLSHKIPPME
Site 244Y1711PPMEEPSYTQDNDLS
Site 245T1712PMEEPSYTQDNDLSE
Site 246S1718YTQDNDLSELISVSQ
Site 247S1722NDLSELISVSQVEAS
Site 248S1729SVSQVEASPSTSSAH
Site 249S1731SQVEASPSTSSAHTP
Site 250S1733VEASPSTSSAHTPSQ
Site 251S1734EASPSTSSAHTPSQI
Site 252T1737PSTSSAHTPSQIASP
Site 253S1739TSSAHTPSQIASPLQ
Site 254S1743HTPSQIASPLQEDTL
Site 255T1749ASPLQEDTLSDVAPP
Site 256S1751PLQEDTLSDVAPPRD
Site 257S1760VAPPRDMSLYASLTS
Site 258Y1762PPRDMSLYASLTSEK
Site 259S1764RDMSLYASLTSEKVQ
Site 260T1766MSLYASLTSEKVQSL
Site 261S1772LTSEKVQSLEGEKLS
Site 262S1779SLEGEKLSPKSDISP
Site 263S1782GEKLSPKSDISPLTP
Site 264S1785LSPKSDISPLTPRES
Site 265T1788KSDISPLTPRESSPL
Site 266S1792SPLTPRESSPLYSPT
Site 267S1793PLTPRESSPLYSPTF
Site 268Y1796PRESSPLYSPTFSDS
Site 269S1797RESSPLYSPTFSDST
Site 270T1799SSPLYSPTFSDSTSA
Site 271S1801PLYSPTFSDSTSAVK
Site 272S1803YSPTFSDSTSAVKEK
Site 273T1804SPTFSDSTSAVKEKT
Site 274S1805PTFSDSTSAVKEKTA
Site 275T1811TSAVKEKTATCHSSS
Site 276T1813AVKEKTATCHSSSSP
Site 277S1816EKTATCHSSSSPPID
Site 278S1817KTATCHSSSSPPIDA
Site 279S1818TATCHSSSSPPIDAA
Site 280S1819ATCHSSSSPPIDAAS
Site 281S1826SPPIDAASAEPYGFR
Site 282Y1830DAASAEPYGFRASVL
Site 283S1835EPYGFRASVLFDTMQ
Site 284S1852LALNRDLSTPGLEKD
Site 285T1853ALNRDLSTPGLEKDS
Site 286S1860TPGLEKDSGGKTPGD
Site 287T1864EKDSGGKTPGDFSYA
Site 288S1869GKTPGDFSYAYQKPE
Site 289Y1870KTPGDFSYAYQKPEE
Site 290Y1872PGDFSYAYQKPEETT
Site 291T1878AYQKPEETTRSPDEE
Site 292T1879YQKPEETTRSPDEED
Site 293S1881KPEETTRSPDEEDYD
Site 294Y1887RSPDEEDYDYESYEK
Site 295Y1889PDEEDYDYESYEKTT
Site 296S1891EEDYDYESYEKTTRT
Site 297Y1892EDYDYESYEKTTRTS
Site 298T1895DYESYEKTTRTSDVG
Site 299T1898SYEKTTRTSDVGGYY
Site 300S1899YEKTTRTSDVGGYYY
Site 301Y1904RTSDVGGYYYEKIER
Site 302Y1905TSDVGGYYYEKIERT
Site 303Y1906SDVGGYYYEKIERTT
Site 304T1912YYEKIERTTKSPSDS
Site 305T1913YEKIERTTKSPSDSG
Site 306S1915KIERTTKSPSDSGYS
Site 307S1917ERTTKSPSDSGYSYE
Site 308S1919TTKSPSDSGYSYETI
Site 309Y1921KSPSDSGYSYETIGK
Site 310S1922SPSDSGYSYETIGKT
Site 311Y1923PSDSGYSYETIGKTT
Site 312T1925DSGYSYETIGKTTKT
Site 313T1930YETIGKTTKTPEDGD
Site 314T1932TIGKTTKTPEDGDYS
Site 315Y1938KTPEDGDYSYEIIEK
Site 316S1939TPEDGDYSYEIIEKT
Site 317Y1940PEDGDYSYEIIEKTT
Site 318T1946SYEIIEKTTRTPEEG
Site 319T1947YEIIEKTTRTPEEGG
Site 320T1949IIEKTTRTPEEGGYS
Site 321Y1955RTPEEGGYSYDISEK
Site 322S1956TPEEGGYSYDISEKT
Site 323Y1957PEEGGYSYDISEKTT
Site 324S1960GGYSYDISEKTTSPP
Site 325T1963SYDISEKTTSPPEVS
Site 326T1964YDISEKTTSPPEVSG
Site 327S1965DISEKTTSPPEVSGY
Site 328S1970TTSPPEVSGYSYEKT
Site 329Y1972SPPEVSGYSYEKTER
Site 330S1973PPEVSGYSYEKTERS
Site 331Y1974PEVSGYSYEKTERSR
Site 332T1977SGYSYEKTERSRRLL
Site 333S1980SYEKTERSRRLLDDI
Site 334S1988RRLLDDISNGYDDSE
Site 335Y1991LDDISNGYDDSEDGG
Site 336S1994ISNGYDDSEDGGHTL
Site 337S2005GHTLGDPSYSYETTE
Site 338Y2006HTLGDPSYSYETTEK
Site 339S2007TLGDPSYSYETTEKI
Site 340Y2008LGDPSYSYETTEKIT
Site 341T2011PSYSYETTEKITSFP
Site 342S2016ETTEKITSFPESEGY
Site 343S2020KITSFPESEGYSYET
Site 344Y2023SFPESEGYSYETSTK
Site 345S2024FPESEGYSYETSTKT
Site 346Y2025PESEGYSYETSTKTT
Site 347S2028EGYSYETSTKTTRTP
Site 348T2031SYETSTKTTRTPDTS
Site 349T2032YETSTKTTRTPDTST
Site 350T2034TSTKTTRTPDTSTYC
Site 351T2037KTTRTPDTSTYCYET
Site 352S2038TTRTPDTSTYCYETA
Site 353T2039TRTPDTSTYCYETAE
Site 354Y2040RTPDTSTYCYETAEK
Site 355Y2042PDTSTYCYETAEKIT
Site 356T2051TAEKITRTPQASTYS
Site 357S2055ITRTPQASTYSYETS
Site 358Y2057RTPQASTYSYETSDL
Site 359S2058TPQASTYSYETSDLC
Site 360Y2059PQASTYSYETSDLCY
Site 361S2062STYSYETSDLCYTAE
Site 362Y2066YETSDLCYTAEKKSP
Site 363T2067ETSDLCYTAEKKSPS
Site 364S2072CYTAEKKSPSEARQD
Site 365S2074TAEKKSPSEARQDVD
Site 366S2086DVDLCLVSSCEYKHP
Site 367S2087VDLCLVSSCEYKHPK
Site 368Y2090CLVSSCEYKHPKTEL
Site 369T2095CEYKHPKTELSPSFI
Site 370S2098KHPKTELSPSFINPN
Site 371S2100PKTELSPSFINPNPL
Site 372S2112NPLEWFASEEPTEES
Site 373T2116WFASEEPTEESEKPL
Site 374S2119SEEPTEESEKPLTQS
Site 375T2124EESEKPLTQSGGAPP
Site 376T2145QGRQCDETPPTSVSE
Site 377T2148QCDETPPTSVSESAP
Site 378S2149CDETPPTSVSESAPS
Site 379S2151ETPPTSVSESAPSQT
Site 380S2153PPTSVSESAPSQTDS
Site 381S2156SVSESAPSQTDSDVP
Site 382T2158SESAPSQTDSDVPPE
Site 383S2160SAPSQTDSDVPPETE
Site 384T2166DSDVPPETEECPSIT
Site 385S2171PETEECPSITADANI
Site 386S2180TADANIDSEDESETI
Site 387S2184NIDSEDESETIPTDK
Site 388T2189DESETIPTDKTVTYK
Site 389T2192ETIPTDKTVTYKHMD
Site 390T2194IPTDKTVTYKHMDPP
Site 391Y2195PTDKTVTYKHMDPPP
Site 392S2209PAPVQDRSPSPRHPD
Site 393S2211PVQDRSPSPRHPDVS
Site 394S2218SPRHPDVSMVDPEAL
Site 395T2243KKDLKEKTKTKKPGT
Site 396T2245DLKEKTKTKKPGTKT
Site 397T2250TKTKKPGTKTKSSSP
Site 398T2252TKKPGTKTKSSSPVK
Site 399S2254KPGTKTKSSSPVKKS
Site 400S2255PGTKTKSSSPVKKSD
Site 401S2256GTKTKSSSPVKKSDG
Site 402S2261SSSPVKKSDGKSKPL
Site 403S2265VKKSDGKSKPLAASP
Site 404S2271KSKPLAASPKPAGLK
Site 405S2280KPAGLKESSDKVSRV
Site 406S2281PAGLKESSDKVSRVA
Site 407S2285KESSDKVSRVASPKK
Site 408S2289DKVSRVASPKKKESV
Site 409T2305KAAKPTTTPEVKAAR
Site 410S2327TKNAANASASKSAKT
Site 411S2329NAANASASKSAKTAT
Site 412S2331ANASASKSAKTATAG
Site 413T2334SASKSAKTATAGPGT
Site 414T2344AGPGTTKTTKSSAVP
Site 415S2347GTTKTTKSSAVPPGL
Site 416Y2362PVYLDLCYIPNHSNS
Site 417S2382EFFKRVRSSYYVVSG
Site 418S2383FFKRVRSSYYVVSGN
Site 419Y2384FKRVRSSYYVVSGND
Site 420Y2385KRVRSSYYVVSGNDP
Site 421T2419WGSNMQVTLIPTHDS
Site 422Y2433SEVMREWYQETHEKQ
Site 423S2460TVVMQDESFPACKIE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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