PhosphoNET

           
Protein Info 
   
Short Name:  NR4A2
Full Name:  Nuclear receptor subfamily 4 group A member 2
Alias:  Immediate-early response protein NOT; Nurr1; Orphan nuclear receptor NURR1; TINUR; Transcriptionally-inducible nuclear receptor
Type:  Nucleus protein
Mass (Da):  66591
Number AA:  598
UniProt ID:  P43354
International Prot ID:  IPI00018033
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003707  GO:0003700  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0031668  GO:0051789  GO:0007165 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11VQAQYGSSPQGASPA
Site 2S16GSSPQGASPASQSYS
Site 3S19PQGASPASQSYSYHS
Site 4S21GASPASQSYSYHSSG
Site 5Y22ASPASQSYSYHSSGE
Site 6S23SPASQSYSYHSSGEY
Site 7Y24PASQSYSYHSSGEYS
Site 8S26SQSYSYHSSGEYSSD
Site 9S27QSYSYHSSGEYSSDF
Site 10Y30SYHSSGEYSSDFLTP
Site 11S31YHSSGEYSSDFLTPE
Site 12S32HSSGEYSSDFLTPEF
Site 13T36EYSSDFLTPEFVKFS
Site 14T47VKFSMDLTNTEITAT
Site 15T54TNTEITATTSLPSFS
Site 16S59TATTSLPSFSTFMDN
Site 17T62TSLPSFSTFMDNYST
Site 18Y67FSTFMDNYSTGYDVK
Site 19Y71MDNYSTGYDVKPPCL
Site 20Y79DVKPPCLYQMPLSGQ
Site 21S84CLYQMPLSGQQSSIK
Site 22S88MPLSGQQSSIKVEDI
Site 23S89PLSGQQSSIKVEDIQ
Site 24Y100EDIQMHNYQQHSHLP
Site 25S110HSHLPPQSEEMMPHS
Site 26S117SEEMMPHSGSVYYKP
Site 27S119EMMPHSGSVYYKPSS
Site 28Y121MPHSGSVYYKPSSPP
Site 29Y122PHSGSVYYKPSSPPT
Site 30S125GSVYYKPSSPPTPTT
Site 31S126SVYYKPSSPPTPTTP
Site 32T129YKPSSPPTPTTPGFQ
Site 33T131PSSPPTPTTPGFQVQ
Site 34T132SSPPTPTTPGFQVQH
Site 35S140PGFQVQHSPMWDDPG
Site 36T160HQNYVATTHMIEQRK
Site 37T168HMIEQRKTPVSRLSL
Site 38S171EQRKTPVSRLSLFSF
Site 39S174KTPVSRLSLFSFKQS
Site 40S177VSRLSLFSFKQSPPG
Site 41S181SLFSFKQSPPGTPVS
Site 42T185FKQSPPGTPVSSCQM
Site 43S188SPPGTPVSSCQMRFD
Site 44S189PPGTPVSSCQMRFDG
Site 45S209MNPEPAGSHHVVDGQ
Site 46T217HHVVDGQTFAVPNPI
Site 47S229NPIRKPASMGFPGLQ
Site 48T246HASQLLDTQVPSPPS
Site 49S250LLDTQVPSPPSRGSP
Site 50S253TQVPSPPSRGSPSNE
Site 51S256PSPPSRGSPSNEGLC
Site 52S258PPSRGSPSNEGLCAV
Site 53T290CKGFFKRTVQKNAKY
Site 54Y297TVQKNAKYVCLANKN
Site 55Y317RRRNRCQYCRFQKCL
Site 56T335MVKEVVRTDSLKGRR
Site 57S337KEVVRTDSLKGRRGR
Site 58S347GRRGRLPSKPKSPQE
Site 59S351RLPSKPKSPQEPSPP
Site 60S356PKSPQEPSPPSPPVS
Site 61S359PQEPSPPSPPVSLIS
Site 62S363SPPSPPVSLISALVR
Site 63S381DSNPAMTSLDYSRFQ
Site 64Y384PAMTSLDYSRFQANP
Site 65S385AMTSLDYSRFQANPD
Site 66Y393RFQANPDYQMSGDDT
Site 67Y407TQHIQQFYDLLTGSM
Site 68T411QQFYDLLTGSMEIIR
Site 69S455VLRLAYRSNPVEGKL
Site 70S485GFGEWIDSIVEFSSN
Site 71Y551GGLNRPNYLSKLLGK
Site 72S553LNRPNYLSKLLGKLP
Site 73T564GKLPELRTLCTQGLQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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