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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLP1R
Full Name:
Glucagon-like peptide 1 receptor
Alias:
Type:
G protein-coupled 7TM receptor
Mass (Da):
53060
Number AA:
463
UniProt ID:
P43220
International Prot ID:
IPI00300576
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004967
GO:0008528
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0007190
GO:0019933
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
G
P
R
P
Q
G
A
T
V
S
L
W
E
T
V
Site 2
S31
R
P
Q
G
A
T
V
S
L
W
E
T
V
Q
K
Site 3
T35
A
T
V
S
L
W
E
T
V
Q
K
W
R
E
Y
Site 4
Y42
T
V
Q
K
W
R
E
Y
R
R
Q
C
Q
R
S
Site 5
S49
Y
R
R
Q
C
Q
R
S
L
T
E
D
P
P
P
Site 6
T51
R
Q
C
Q
R
S
L
T
E
D
P
P
P
A
T
Site 7
Y69
C
N
R
T
F
D
E
Y
A
C
W
P
D
G
E
Site 8
S79
W
P
D
G
E
P
G
S
F
V
N
V
S
C
P
Site 9
Y101
S
V
P
Q
G
H
V
Y
R
F
C
T
A
E
G
Site 10
S116
L
W
L
Q
K
D
N
S
S
L
P
W
R
D
L
Site 11
S117
W
L
Q
K
D
N
S
S
L
P
W
R
D
L
S
Site 12
S124
S
L
P
W
R
D
L
S
E
C
E
E
S
K
R
Site 13
S129
D
L
S
E
C
E
E
S
K
R
G
E
R
S
S
Site 14
S135
E
S
K
R
G
E
R
S
S
P
E
E
Q
L
L
Site 15
S136
S
K
R
G
E
R
S
S
P
E
E
Q
L
L
F
Site 16
S219
H
Q
W
D
G
L
L
S
Y
Q
D
S
L
S
C
Site 17
Y220
Q
W
D
G
L
L
S
Y
Q
D
S
L
S
C
R
Site 18
Y289
V
P
W
G
I
V
K
Y
L
Y
E
D
E
G
C
Site 19
Y305
T
R
N
S
N
M
N
Y
W
L
I
I
R
L
P
Site 20
T378
M
D
E
H
A
R
G
T
L
R
F
I
K
L
F
Site 21
S416
V
Q
L
E
F
R
K
S
W
E
R
W
R
L
E
Site 22
S431
H
L
H
I
Q
R
D
S
S
M
K
P
L
K
C
Site 23
S432
L
H
I
Q
R
D
S
S
M
K
P
L
K
C
P
Site 24
T440
M
K
P
L
K
C
P
T
S
S
L
S
S
G
A
Site 25
S441
K
P
L
K
C
P
T
S
S
L
S
S
G
A
T
Site 26
S442
P
L
K
C
P
T
S
S
L
S
S
G
A
T
A
Site 27
S444
K
C
P
T
S
S
L
S
S
G
A
T
A
G
S
Site 28
S445
C
P
T
S
S
L
S
S
G
A
T
A
G
S
S
Site 29
T448
S
S
L
S
S
G
A
T
A
G
S
S
M
Y
T
Site 30
S451
S
S
G
A
T
A
G
S
S
M
Y
T
A
T
C
Site 31
S452
S
G
A
T
A
G
S
S
M
Y
T
A
T
C
Q
Site 32
Y454
A
T
A
G
S
S
M
Y
T
A
T
C
Q
A
S
Site 33
T455
T
A
G
S
S
M
Y
T
A
T
C
Q
A
S
C
Site 34
S461
Y
T
A
T
C
Q
A
S
C
S
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation